The present invention provides methods of utilizing a cranial implant to affect a behavior or condition of a person. The method generally comprises steps of 1) obtaining signals from the cranial implant of the person, 2) processing the obtained signals to produce a visually renderable image, and 3) rendering the image on an intraocular display.

A method, system, and/or apparatus for automatically monitoring for possible mental or physical health concerns. The method or implementing software application uses or relies upon location information available on the mobile device from any source, such as cell phone usage and/or other device applications. The method and system automatically learns user activity patterns and detects significant deviations therefrom. The deviations are automatically analyzed for known correlations to mental or physical concerns, which can then be automatically communicated to a relevant friend, family member, and/or medical professional.

A method for diagnosing a joint condition includes in one embodiment: creating a 3d model of the patient specific bone; registering the patient's bone with the bone model; tracking the motion of the patient specific bone through a range of motion; selecting a database including empirical mathematical descriptions of the motion of a plurality actual bones through ranges of motion; and comparing the motion of the patient specific bone to the database.

A monitoring device configured to be attached to a subject includes a photoplethysmography (PPG) sensor configured to measure physiological information from the subject, and at least one processor configured to process signals from the PPG sensor to determine heart rate and RR-interval (RRi) for the subject, and to determine a heart rate pattern for the subject over a period of time. The at least one processor is configured to change a sampling frequency of the PPG sensor for determining RRi in response to the determined heart rate pattern. The at least one processor is configured to reduce the sampling frequency of the PPG sensor in response to determining a pattern of heart rate below a threshold.

Personal diagnostic devices including diagnostic patches (bio-patches) and interactive medical bracelets (bio-bracelets) are provided with a skin/patch interface, at least one analysis layer, a signal processing layer, and a user output interface. Embodiments of the interactive diagnostic devices may include micro-fluidic circuits with reaction chambers, analysis chambers, mixing cambers, and various pre-disposed chemistries or reagents for performing a wide verity of tests by transdermal transport of blood or perspiration. Sample collection chambers for the fluidic circuit may include minimally invasive tubules that penetrate the skin surface to acquire blood samples from capillaries near the epidermis. Alternate implementations of the personal diagnostic device may be equipped with logic processing, input/output devices, acoustic microphones, cryogenic circuits, embedded processors, electrical control circuitry, and battery current sources or photovoltaic sources of electrical power.

A multi-target vital sign detection system includes a transmitter, a receiver and a processor. The transmitter is configured to transmit a millimeter wave signal to a detection area, and the receiver is configured to receive a reflecting millimeter wave signal reflected by a plurality of targets in the detection area. The processor is configured to: generate signal strength versus distance data by analyzing the received reflecting millimeter wave signal; perform an extreme value reserving process to generate signal extreme value versus distance data; perform a peak search algorithm to obtain a peak list including a plurality of peak values and a plurality of corresponding peak distances; generate a distance array including a plurality of distance variables; and perform a vital sign detection algorithm to generate multiple sets of vital sign data.

Methods and devices to monitor an analyte in body fluid are provided. Embodiments include continuous or discrete acquisition of analyte related data from a transcutaneously positioned in vivo analyte sensor automatically or upon request from a user. The in vivo analyte sensor is coupled to an electronics unit holding a memory with instruction to cause processing circuitry to initiate a predetermined time period that is longer than a predetermined life of the sensor, during the predetermined time period, convert signals from the sensor related to glucose to respective corresponding glucose levels, without relying on any post-manufacture independent analyte measurements from a reference device, and at the expiration of the predetermined time period, disable, deactivate, or cease use of one or more feature.

Provided here are non-invasive methods for evaluating functional connectivity patterns in localized brain regions of a patient involving application of a MS-specific functional meta-analytic connectivity model in resting-state functional magnetic resonance imaging (rsfMRI) data to provide patients with appropriate medical care in response to output from the model.

Disclosed herein is a biomedical data analysis program (“MUSTER”) that facilitates extraction of key features from big data sets and can be leveraged for different discovery-oriented goals and purposes. In particular, the disclosed biomedical data analysis program is used for mutation-survival interrogation and provides an evolutionary probability distribution for gene signature identification.

A system and method for collecting operation data associated with a medical apparatus including an internal device implanted in a subject and an external device that is magnetically-coupled to and drives the internal device. The medical apparatus may be monitored to obtain raw data associated with the operation of the medical apparatus and one or more calculations may be performed on the raw data, wherein the raw data and/or calculated values may be associated with voiding frequency and voiding volume of the subject. A report may be generated from the raw data and/or calculated values. In addition, one or more signals may be sent to the external device and/or a docking station, or communicated by other means, to indicate to the subject that the operation of the medical apparatus should be altered.