A roll sheet type sample collection kit according to an embodiment includes a fixing bar provided as a member having a given length, a collection sheet rolledly fixed to one end of the fixing bar to attachedly collect the sample thereonto, a support bar adapted to allow the fixing bar and the collection sheet to protrude from one side thereof and to be grasped while the sample is being collected, and a cap detachably mounted to surround the fixing bar and the collection sheet protruding from the support bar. The roll sheet type sample collection kit performs a sample test in a gentle and accurate manner, and easily removes a portion where the sample is collected therefrom so as to perform the sample test, thereby enhancing quickness and conveniences in the sample test.

Cerebrospinal fluid (CSF) drainage systems. A system includes a conduit having a proximal end and a distal end. The conduit receives the CSF from a patient from the proximal end. The system includes a collection chamber coupled to the distal end. The collection chamber collects the CSF. The system includes a valve positioned on the conduit. The valve controls CSF flow into the collection chamber. The system includes a camera that captures an image of the CSF within the collection chamber. The system includes a processor coupled to the camera. The processor measures a flow rate of the CSF based on the image and controls the first valve to open for a first predetermined period and close for a second predetermined period until a determination of a predetermined amount of the CSF being drained from the patient is made by the processor based on the flow rate.

An interstitial fluid removal device including a first needle, a second needle, a fluid injector and an interstitial fluid extractor. The first needle is configured for insertion in a tissue of a multicellular organism to provide a fluid inlet channel. The second needle is configured for insertion in a tissue of a multicellular organism to provide an interstitial fluid outlet channel. The fluid injector is arranged in fluid communication with both a fluid source and the first needle and configured to inject a fluid in the tissue of the multicellular organism. The fluid extractor is arranged in fluid communication with the second needle and configured to extract interstitial fluid from the tissue of the multicellular organism. The fluid injector and the fluid extractor are independently and/or simultaneously operable with respect to each other.

Samples, systems for collecting samples, and methods of preserving samples from menstrual fluid are provided.

A universal single-handed device for self-collection of a biological sample is described herein. The single-handed device may comprise a sheath comprising a distal end for insertion into a portion of a user's body, a shaft at least partially within the sheath, having a collection head for collecting the biological sample positioned at the distal end thereof, and an actuator coupled to the shaft to transition the distal end between an open configuration and a closed configuration. The collection head is covered by the distal end in the closed configuration and is exposed when the distal end is in the open configuration.

The disclosed apparatus, systems and methods relate to devices, systems and methods for the collection of bodily fluids. The collector can make use of microfluidic networks connected to collection sites on the skin of a subject to gather and shuttle blood into a removable cartridge. The collected fluid is supplied to substrate for drying, storage and transport.

In one aspect, a sample collection device for collecting a biological sample is disclosed, which comprises a sample-receiving cup having a body that extends from a proximal opening to a distal opening, where the proximal opening is configured for receiving a biological sample. The sample collection device further includes a sensor comprising at least one sensing unit, where the sensor is sealingly connected to the distal opening of the sample-receiving cup such that the sensing unit is exposed to the distal opening. A reservoir for storing one or more sample-processing reagents is provided in the fluid-receiving cup such that the sensing unit is in fluid contact with the reagent(s) stored in the reservoir. A frangible membrane separates the reservoir from the proximal opening.

Methods and devices to capture and analyze aerosolized particles such as protein biomarkers and their truncated proteoforms characteristic of a disease, including a respiratory disease, in exhaled breath to enable rapid detection of diseases are disclosed. The disclosed methods and systems selectively capture aerosolized particles using a packed bed column. The captured particles are then eluted using one or more solvents and analyzed using devices including mass spectrometry.

The present invention relates to a method for determining an analyte using surface enhanced RAMAN spectroscopy and to a device which is suitable for this purpose.

In some embodiments, a device may include an intraventricular access device and an infusion device. The intraventricular access device may include more than one catheter and a container. In some embodiments, the catheter may include an aspiration lumen and an infusion lumen. A distal end of the intraventricular portion of the catheter may be positionable, during use, in a subject's brain fluid. In some embodiments, the container may be coupled to a proximal end of the aspiration lumen. The proximal end of the aspiration lumen may be in fluid communication with the container. In some embodiments, the container may include a barrier positioned between a proximal opening of the aspiration lumen and at least a portion of the infusion lumen adjacent to and/or associated with the container. The barrier may inhibit penetration of a surgical instrument.