A specimen collection container having a separation chamber includes a first chamber, a second chamber, and a valve located between the first chamber and the second chamber. In an open position, the valve permits fluid communication between the first chamber and the second chamber. In a closed position, the valve maintains fluid isolation between the first chamber and the second chamber. A fluid stream passes from the first chamber to the second chamber through the valve permitting a predetermined volume of fluid to pass from the first chamber to the second chamber. When the predetermined volume of fluid passes to the second chamber, the valve transitions from the open position to the closed position so that additional fluid of the fluid stream received by the first chamber is maintained in the first chamber in fluid isolation from the predetermined volume of fluid contained in the second chamber.

A female urinary device including a urine stream collection container having a discharge opening and a stream collection opening, the stream collection opening being configured to surround and isolate a urethral opening, an internal baffle that cooperates with at least a urine sample container to provide a spillway to the discharge opening, where the spillway provides urine passage to a collection tank, and a probe configured for interior engagement with a vaginal opening for placement of the stream collection opening relative to the urethra opening.

A containment device for biological samples, which comprises: a first vessel for depositing a biological sample, a lid adapted to engage the first vessel, a hermetically-sealed chamber, adapted to contain a preservative, arranged between the lid and the first vessel, elements of generating a passage between the hermetically-sealed chamber and the first vessel for the descent of the preservative from the chamber to the first vessel; the hermetically-sealed chamber is defined by a second vessel, which is inserted into the first vessel with the filling opening directed toward the lid, and by the lid itself, closed onto the first vessel, the elements of generating a passage between the hermetically-sealed chamber and the first vessel comprise a region with a pre-fracture that is defined on the second vessel and a corresponding presser that extends from the lid and is in a position to encounter the region with a pre-fracture.

The invention relates to a biological sampling and storage container comprising a top cover and a bottom cover adapted to fit onto each other; and a sampling element having a proximal end onto which the top cover fits and a distal end onto which the bottom cover fits, said sampling element further comprising a sampling container comprising a sampling chamber for accepting the biological sample; an aliquoting element removably mounted on and in said sampling container, said aliquoting element comprising a structural element onto which one or more aliquoting chambers are positioned; and optionally, an ejector removably mounted onto said aliquoting element, wherein the ejector comprises an ejector wand fitting into the aliquoting chambers.

The disclosure relates to devices, solutions and methods for collecting and processing samples of bodily fluids containing cells (as well as embodiments for the collection, and processing and/or analysis of other fluids including toxic and/or hazardous substances/fluids). In addition, the disclosure relates generally to function genomic studies and to the isolation and preservation of cells from saliva and other bodily fluids (e.g., urine), for cellular analysis. With respect to devices for collection of bodily fluids, some embodiments include two mating bodies, a cap and a tube (for example), where, in some embodiments, the cap includes a closed interior space for holding a sample preservative solution and mates with the tube to constitute the (closed) sample collection device. Upon mating, the preservation solution flows into the closed interior space to preserve cells in the bodily fluid. The tube is configured to receive a donor sample of bodily fluid (e.g., saliva, urine), which can then be subjected to processing to extract a plurality of cells. The plurality of cells can be further processed to isolate one and/or another cell type therefrom. The plurality of cells, as well as the isolated cell type(s), can be analyzed for functional genomic and epigenetic studies, as well as biomarker discovery.

An appliance for sealing elastic hoses with a sleeve, which is plastically deformable and slipped onto the hose, has two jaws which are movable towards and away from each other. One jaw has two straight bars which project towards the other jaw and extend transversely of the sleeve to make two transverse indentations in the sleeve and the hose when the jaws are moving towards each other. The same jaw has a cutting edge which projects towards the other jaw and is directed transversely of the sleeve, the cutting edge making a substantially transverse cutting indication in the sleeve and the hose when the jaws are moving towards each other.

Biological samples, such as saliva, are commonly collected on a swab and subsequently transferred to an absorbent storage medium. Embodiments of the present invention provide a biological sample collection device 600 comprising a collection portion 620 and a body portion 610, the body portion including a holding portion 652 for holding a biological sample storage medium (618 FIG. 1), and a sample collection/transfer means. The collection portion 620 can be arranged in a first position shown in FIG. 4, separated from the body portion for collecting a sample. The device employs depressible latches (630, 640 FIG. 6) to control the movements of the collection portion.

An embodiment of the claimed invention is directed to a method that greatly streamlines and reduces costs for tissue preparation, preservation, long-term storage and sample retrieval for molecular analysis using a method based on dried blood spot (DBS) technology. In this method, a small needle punch sample of freshly excised tissue will be homogenized in stabilizing reagent and inserted into a device containing absorbent material and drying agent. This device is suitable for long-term sample storage at ambient temperature and allows for easy removal of sections for biomarker analysis.

The present invention provides a device that allows the collection of urine samples in patients who are not self-sufficient, providing a simple method to operate both for the patient and for the health personnel. The device is equipped with a primary collection system and a secondary collection system, which allows to obtain a complete sample of urine that can be transported for further analysis in the laboratory.

An endoscope system for delivering a fluid to a patient and retrieving for diagnostic purposes from the patient a specimen. The system includes an endoscope, a fluid container containing a fluid, and a first specimen container for receiving a specimen. The endoscope system has a first user selectable state and a second user selectable state, where the endoscope system in the first user selectable state is configured to automatically deliver the fluid from the fluid container to the patient and in the second user selectable state is configured to automatically retrieve a specimen from the patient and provide the specimen to the first specimen container.