An expansile member that may be used on a delivery device or may be used for occlusive purposes within the vasculature.

A method for implanting a medical device for implantation in a mammal joint. The method comprising the steps of creating an opening reaching from outside of the human body into the joint, providing said artificial contacting surface to said joint, fixating the artificial contacting surface to the joint, implanting said reservoir in the human body, and lubricating the artificial contacting surface with use of a lubricating fluid contained in said reservoir.

Methods and systems for providing feedback to guide selection of an artificial bone flap. A user interface for planning a neurosurgical procedure is provided, the neurosurgical procedure including closing of an opening in a portion of a patient's skull using an artificial bone flap. 3D dimensions of the opening are determined using at least pre-operative three-dimensional (3D) imaging data. One or more parameters for selecting an artificial bone flap are determined, where the one or more parameters are based on at least the 3D dimensions of the opening. Output indicating one or more recommended available artificial bone flaps suitable for closing the opening is provided, the recommendation being based on the determined one or more parameters.

Devices and methods are described for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body. The device may have a thromboresistant cover at a proximal end. The frame may have recapture struts inclining radially outwardly from a central hub. The frame may have axially extending side wall struts, with adjacent pairs of side wall struts joined at one or more apexes. Anchors extend from the frame and into the foam to engage tissue.

Disclosed embodiments include devices and methods for shaping, bending, and/or volumetrically reducing rigid cartilaginous structures, such as hyaline cartilage in the septum. In the case of septal cartilage, shaping, bending, or reducing the cartilage would be useful for reducing nasal obstruction or to improve the cosmetic appearance of the nose.

A tissue closure device can include a structural material and a stimulus responsive material on or in the structural material. The structural material can be biodegradable and/or bioabsorbable (e.g., biocompatible natural and/or semi-natural and/or synthetic polymer). The stimulus responsive material can be a particle, such as a nanoparticle. The structural material is shaped as a suture, staple, screw, patch, adhesive, sealant, or the like. A biologically active agent can be included. A method of promoting wound healing can include: approximating tissue portions; and stimulating the stimulus responsive material with a stimulus to cause the tissue portions of the wound to adhere to each other. The stimulus is selected from optical, electrical, thermal, chemical, mechanical, magnetic, acoustic, pressure, shear, biological, or enzymatic sources.

A medical device for repairing soft tissue is disclosed. The medical device includes a cannulated probe positionable a tear in the soft tissue and a stop. The cannulated probe has an inlet about a proximal end and at least one outlet about a distal end with a lumen therethrough. The inlet is operatively connectable to an adhesive source to receive the adhesive therein. The outlet(s) is/are positionable about the tear to emit the adhesive about the tear. The stop is disposable about a periphery of the probe a distance from the inlet, and is positionable adjacent a surface of the soft tissue to terminate advancement of the cannulated probe into the soft tissue whereby a delivery portion of the cannulated probe is positionable about the soft tissue to deliver the adhesive about the tear.

The present invention relates to a sutureless method of repairing soft tissue defects in soft tissue including ligaments such as anterior cruciate ligaments (ACLs). In particular, the present invention relates a sutureless method of repairing soft tissue defect comprising: (i) providing a collagen-containing patch adapted to enclose at least a portion of said soft tissue defect; (ii) contacting said soft tissue defect and/or collagen-containing patch with a sensitizer; (Hi) enclosing said soft tissue defect in said collagen-containing patch to produce a bioactive chamber; and (iv) adhering said collagen-containing patch to said soft tissue defect without sutures.

The present disclosure relates to a method for vacuum expansion of a paste prior to freeze-drying said paste to achieve a dry paste composition which reconstitutes efficiently to form a flowable paste upon addition of an aqueous medium. The present disclosure further relates to a syringe for retaining a dry paste composition in a vacuum.

A surgical end effector comprising a staple cartridge, an anvil, and a compressible portion intermediate the staple cartridge and the anvil is disclosed. The compressible portion comprises a plurality of tubular members.