In a first aspect of the subject invention, an iris expander is provided which includes a non-metallic, unitary, multi-segmented body which is expandable from a first state to a second state. The second state defines a larger footprint than the first state with the body being defined by a plurality of segments connected by living hinges. In a further aspect, an iris expander is provided which includes a multi-segmented body that is expandable from a first state to a larger-footprint second state. At least one aperture is formed in the body with a channel extending therefrom embedded in the body such that no portion thereof is exposed externally of the body. The channel is formed to accommodate a portion of an instrument for causing adjustment of the body with avoidance of direct contact of the instrument with the tissue of the iris.

Several heart wall remodeling devices and methods are disclosed. One heart wall remodeling device includes a trimming tool for trimming a line within a patient. The trimming tool includes an actuator for manipulation by a user, a moveable inner shaft coupled to the actuator, and an outer sleeve coupled to the inner shaft. The outer shaft includes a backstop disposed along an inner wall of the outer sleeve and a channel disposed between a first end and a second end of the outer sleeve. The inner shaft includes an inner shaft, a compressible member, and a cutter.

An occlusion device includes a braided mesh body and at least one pinch member. The braided mesh body comprises plural strands each having a first end portion and a second end portion. The plural strands fold over to bring the second end portions of the plural strands adjacent to the first end portions of the plural strands forming a double-layer of the braided mesh body. In an example occlusion device, at least one of the plural strands is radiopaque, and the at least one pinch member is non-radiopaque.

A fracture fixation system includes an intramedullary nail having a proximal nail hole, wherein an inner surface of the proximal nail hole has a non-circular shape in a plane perpendicular to an axis along which the proximal nail hole extends; a plate having an inner surface for placement against a surface of a bone, the plate defining a proximal plate hole adjacent a proximal end of the plate extending through the plate; and a peg extending along a peg axis and configured for insertion into the proximal nail hole, wherein a body of the peg has an outer surface defining a non-circular shape in a plane perpendicular to the peg axis, the peg further including a lateral end adjacent to the body and configured to engage the proximal plate hole, the lateral end having a reduced cross-section that is smaller than a maximum cross-section of the body of the peg.

A conveying apparatus includes a conveying catheter. An insulation catheter over the conveying catheter, a conductive catheter over the outside of the insulation catheter, and a support spring connected to the conveying catheter; the support spring includes a second cathode connected to the conveying steel catheter via a conductive wire; the second cathode includes a second anode provided with a separation point, and connected to the conductive catheter through an anode conductive wire; the anode conductive wire and the cathode conductive wire run through the conveying catheter; the second anode, the anode conductive wire and the conductive catheter form a positive path connected to a positive electrode; the second cathode, the cathode conductive wire and the conveying catheter form a negative path, connected to a negative electrode; and the second anode and the second cathode conduct the positive path and the negative path through electrolyte in blood.

A device (15, 50, 55, 60, 100, 200) for altering blood flow characteristics in a vessel (20), the device (15, 50, 55, 60, 100, 200) comprising: a cuff (10) configured to be surgically positioned around a portion of the vessel (20); a first pad (40) located on an internal wall of the cuff (10), wherein the pad (40): locally reduces a cross-sectional area of a passageway (25) extending through the cuff (10) and/or defines a passageway (25) within the cuff (10) which is non-linear.

The present invention relates to a surgical device for clamping in tissue, wherein the surgical device comprises a first clamp, a second clamp, and an elongated dimensionally stable connector and its use within a minimally invasive or open surgical treatment for effecting tissue to be self-hold.

An assembly of a medical delivery device includes an inner sleeve including a flange at a proximal end. The flange includes one or more through holes. The assembly also includes an outer sleeve movably coupled to the inner sleeve. A distal tip of the outer sleeve includes a plurality of openings for delivering an adhesive to a treatment site. The assembly further includes a cavity formed between the inner sleeve and the outer sleeve and configured to hold the adhesive prior to the delivering. The assembly yet further includes one or more actuators connected to a proximal end of the outer sleeve and extended via the one or more through holes to a handle of the medical delivery device. Actuation of the one or more actuators moves one of the inner sleeve or the outer sleeve relative to the other to cause the delivering of the adhesive.

A method for forming a surgical snare, the method comprising: providing a plurality of filaments; braiding the plurality of filaments together so as to form a braided tubular construct comprising: a proximal tube having an open proximal end, an open distal end, and a proximal tube lumen extending there between; a distal tube having an open proximal end, an open distal end, and a distal tube lumen extending there between; and a loop region disposed between the distal end of the proximal tube and the proximal end of the distal tube, the loop region comprising at least one loop structure, the at least one loop structure comprising at least three of the plurality of filaments braided together; inserting the distal end of the distal tube into the open distal end of the proximal tube and into the proximal tube lumen such that (i) the distal tube is disposed in the proximal tube lumen such that the at least one loop structure extends distally of the distal end of the proximal tube in the form of at least one loop, and (ii) the distal tube lumen extends from a point located distal to the proximal end of the proximal tube to the at least one loop.

Disclosed are vascular occluder, kit and method of use thereof. The vascular occluder includes an occluder body extending longitudinally between an occluder body distal end and an occluder body proximal end. The occluder body is elastically compressible longitudinally from a preliminary deployed configuration to a compressed deployed configuration. Vascular occluder includes a tension member configured to tether the occluder body proximal end to the occluder body distal end and to tighten therebetween when the occluder body is in the compressed deployed configuration. The occluder body includes a proximal tubular body segment and a distal tubular body segment, and when in the compressed deployed configuration, the proximal tubular body segment is located inside of, and/or provides structural support to, the distal tubular body segment.