A medical device, comprising a handle, wherein the handle includes a movable body and a stationary body; an end cap, the end cap comprising an inner cap and an outer cap, wherein the inner cap is coupled to the movable body by a control element such that movement of the movable body relative to the stationary body extends the inner cap relative to the outer cap; and a patch disposed between the inner cap and the outer cap such that movement of the inner cap relative to the outer cap at least partially deploys the patch.

Described herein is a patch delivery assembly for treating a target site and a method for deploying the same. The patch delivery assembly includes a patch installation frame having a self-expanding body extending between a proximal end and an open distal end and defining a lumen therethrough. The patch delivery assembly also includes a delivery cable having a distal end coupled to the proximal end of the patch installation frame and further defining the lumen, and a securement device extending through the lumen defined through the delivery cable and the patch installation frame, the securement device terminating in a distal working end including a securement mechanism. In a deployment configuration of the patch delivery assembly, the patch delivery assembly further includes a patch releasably coupled to the distal end of the patch installation frame, for securement to tissue of the target site using the securement mechanism.

An example anchor-manipulation tool includes (i) at a distal portion of the tool, an anchor-engaging element and an actuator, (ii) at an extracorporeal proximal portion of the tool, a controller, and (iii) a flexible longitudinal member extending between the proximal portion and the distal portion. The distal portion of the tool can be transluminally advanced to an anchor that is intracorporeally implanted in a subject. Subsequently, the anchor-engaging element can be engaged with an eyelet defined by a head of the anchor. Subsequently, the controller can be used to transition the tool into an articulatably-coupled state in which: (i) the eyelet at least in part inhibits movement of the anchor-engaging element away from the anchor, and (ii) the distal portion of the anchor-manipulation tool is deflectable with respect to the anchor. Subsequently, the anchor can be de-anchored by using the anchor-manipulation tool to apply a de-anchoring force to the eyelet.

In a first aspect of the subject invention, an iris expander is provided which includes a non-metallic, unitary, multi-segmented body which is expandable from a first state to a second state. The second state defines a larger footprint than the first state with the body being defined by a plurality of segments connected by living hinges. In a further aspect, an iris expander is provided which includes a multi-segmented body that is expandable from a first state to a larger-footprint second state. At least one aperture is formed in the body with a channel extending therefrom embedded in the body such that no portion thereof is exposed externally of the body. The channel is formed to accommodate a portion of an instrument for causing adjustment of the body with avoidance of direct contact of the instrument with the tissue of the iris.

A first element (91) includes a first arm (92) and a second arm coupled thereto and having a concavity (103) facing the first arm and defining a space (96). In an open state, a tissue anchor portion (46) moves into the space through a gap between distal portions (94) of the first and second arms. In the closed state, the anchor portion is not movable through the gap. A second element (82) is movable with respect to the first element, such that, while the portion (46) of the anchor (40) is within the space, and the first element is in the closed state, in a first position of the second element, the portion of the anchor is movable within the space, and in a second position of the second element, the second element applies torque to the anchor by rotating the second element. Other embodiments are also described.

A tissue interface module has an applicator chamber on a proximal side of the tissue interface module and a tissue acquisition chamber on a distal side of the tissue interface module. The applicator chamber may include: an opening adapted to receive the applicator; an attachment mechanism positioned in the applicator chamber and adapted to attach the tissue interface module to the applicator; a sealing member positioned at a proximal side of the applicator chamber; and a vacuum interface positioned at a proximal side of the applicator chamber and adapted to receive a vacuum inlet positioned on a distal end of the applicator. The invention also includes corresponding methods.

The invention relates to an ultrasonic generator for supplying an electrical power for fragmenting calculi, the ultrasonic generator being assignable a sonotrode, an ultrasonic vibration excitation means for exciting a vibration of the at least one sonotrode, and optionally a force generation apparatus for generating a force for moving a projectile for shock excitation of the sonotrode, with the ultrasonic vibration excitation means being excitable at a vibration frequency by means of the ultrasonic generator by supplying an AC voltage, and the ultrasonic generator comprising a measuring apparatus with at least one measuring unit for measuring a time profile of a voltage and/or current, and an open-loop and/or closed-loop control apparatus for adjusting an electrical power suppliable by the ultrasonic generator to the ultrasonic vibration excitation means, with the measuring apparatus comprising at least one resistor arranged in parallel with the at least one measuring unit and optionally a capacitor arranged in parallel with the measuring unit, wherein the measuring apparatus comprises, in parallel with the at least one measuring unit, at least one suppressor diode for suppressing overvoltage. The invention also relates to a lithotripsy device and a method for operating and controlling a lithotripsy device.

A system for treating a vascular region includes an elongate catheter shaft having a distal end region, with an inner lumen formed in the elongate shaft and a fluid delivery lumen formed in the elongate shaft adjacent to the inner lumen. A treatment core is disposable within the inner lumen, and has a plurality of ultrasound transducers that are adapted to move between a straight configuration and a helical configuration and to provide constructive interference when in the helical configuration.

The present invention relates to a surgical device for clamping in tissue, wherein the surgical device comprises a first clamp, a second clamp, and an elongated dimensionally stable connector and its use within a minimally invasive or open surgical treatment for effecting tissue to be self-hold.

A method for forming a surgical snare, the method comprising: providing a plurality of filaments; braiding the plurality of filaments together so as to form a braided tubular construct comprising: a proximal tube having an open proximal end, an open distal end, and a proximal tube lumen extending there between; a distal tube having an open proximal end, an open distal end, and a distal tube lumen extending there between; and a loop region disposed between the distal end of the proximal tube and the proximal end of the distal tube, the loop region comprising at least one loop structure, the at least one loop structure comprising at least three of the plurality of filaments braided together; inserting the distal end of the distal tube into the open distal end of the proximal tube and into the proximal tube lumen such that (i) the distal tube is disposed in the proximal tube lumen such that the at least one loop structure extends distally of the distal end of the proximal tube in the form of at least one loop, and (ii) the distal tube lumen extends from a point located distal to the proximal end of the proximal tube to the at least one loop.