The present invention includes methods for handling live cell compositions in non-nutritive buffer. The cells in the compositions maintain their identity and functional characteristics after being stored in non-nutritive media up to about 72 hours. The storage method enables the cells to be manufactured at a processing facility and shipped to a point of care site. The invention also includes compositions that have been stored in non-nutritive buffer at storage temperatures while maintaining the functional characteristics.

The present invention includes methods for handling live cell compositions in non-nutritive buffer. The cells in the compositions maintain their identity and functional characteristics after being stored in non-nutritive media up to about 72 hours. The storage method enables the cells to be manufactured at a processing facility and shipped to a point of care site. The invention also includes compositions that have been stored in non-nutritive buffer at storage temperatures while maintaining the functional characteristics.

Container filling systems are described herein. A container filling system includes a container assembly, a nozzle, a first roller and a second roller. The container assembly includes a plurality of containers, each having a container volume and a fluid manifold defining a fluid pathway, wherein the fluid pathway is in fluid communication with the container volume of each of the plurality of containers. The nozzle is in fluid communication with the fluid pathway, wherein the nozzle directs flow from a fluid source into the fluid pathway. The nozzle separates the fluid manifold into a first portion and a second portion to permit the fluid manifold to advance relative to the nozzle.

The disclosure relates to a transfer device of a capsule filling machine for transferring at least one capsule from a capsule receptacle of a capsule segment to a downstream process station, and to a capsule filling machine having such a transfer device. The transfer device includes a transport segment having at least one transport receptacle, which extends along a vertical longitudinal axis, wherein the transport receptacle is configured as a clamping receptacle having a clamping element, acting radially with respect to the longitudinal axis of the transport receptacle, for the capsule.

The disclosure relates to a transfer device of a capsule filling machine for transferring at least one capsule from a capsule receptacle of a capsule segment to a downstream process station, and to a capsule filling machine having such a transfer device. The transfer device includes a transport segment having at least one transport receptacle, which extends along a vertical longitudinal axis, wherein the transport receptacle is configured as a clamping receptacle having a clamping element, acting radially with respect to the longitudinal axis of the transport receptacle, for the capsule.

A packaging unit and method for packaging pharmaceuticals into pouches. The packaging unit includes a feed stock roll to form pouches and an electronic processor electrically coupled to the packaging equipment. The electronic processor is configured to determine an amount of pharmaceuticals being loaded into the pouch, determine a length of the pouch based on the amount of pharmaceuticals, and control the packaging equipment to form the pouch having the length.

A packaging unit and method for packaging pharmaceuticals into pouches. The packaging unit includes a feed stock roll to form pouches and an electronic processor electrically coupled to the packaging equipment. The electronic processor is configured to determine an amount of pharmaceuticals being loaded into the pouch, determine a length of the pouch based on the amount of pharmaceuticals, and control the packaging equipment to form the pouch having the length.

A plural-mode automatic medicament packaging system. In embodiments, the system may include an automatic dispensing machine including an automatic medicament dispensing unit and may further include pouch packaging and blister package packaging units. The medicament dispensing unit may include one or more storage and dispensing units which store and dispense medicaments. Medicaments output from the medicament dispensing unit may be packaged in a pouch package by the pouch packaging unit. Alternatively, a diverter may direct medicaments output from the medicament dispensing unit to the pouch package packaging unit for packaging in a blister package. A single automatic medicament packaging system can package medicaments in different types of packaging providing a pharmacy with the opportunity to package medicaments in the form of packaging most appropriate to meet patient needs.

A plural-mode automatic medicament packaging system. In embodiments, the system may include an automatic dispensing machine including an automatic medicament dispensing unit and may further include pouch packaging and blister package packaging units. The medicament dispensing unit may include one or more storage and dispensing units which store and dispense medicaments. Medicaments output from the medicament dispensing unit may be packaged in a pouch package by the pouch packaging unit. Alternatively, a diverter may direct medicaments output from the medicament dispensing unit to the pouch package packaging unit for packaging in a blister package. A single automatic medicament packaging system can package medicaments in different types of packaging providing a pharmacy with the opportunity to package medicaments in the form of packaging most appropriate to meet patient needs.

An improved paperboard pouch comprising a multilayer substrate and a method of making the same is provided. The multilayer paperboard pouch comprises an outer surface and an inner surface, wherein one of the surfaces is defined as a food contact surface. In the depicted embodiment, the properties of the polymer layer are chosen to provide adequate mechanical and barrier protection to the paper-based pouch formed on the conventional pouch-forming equipment. A method of manufacturing a multilayer paperboard pouch using conventional bag-making equipment (“CBME”) running at normal production speed for making standard plastic pouches is also provided. First, a paper is extrusion-coated and then the CBME is configured with a feeder for feeding an extrusion-coated paper intermittently for a length along a feeding path; a cutter disposed at a position predetermined for cutting one of the layers of the coated paper and forming a first side gusset, a second side gusset and a bottom gusset portions and for folding each of a first side gusset, a second side gusset and a bottom gusset portions into halves along a center line extending longitudinally thereof; and a sealer for sealing the layers of the polymer with the layers of the bottom gusset portion and the layers of the first and second gusset portions, respectively to form the finished multilayer paperboard pouch ready for sale and distribution to various retailers. It is to be noted that in the depicted embodiment various closure constructions and mechanism can be used for heat sealing the finished pouches.