An adapter is configured to hold a flip-top vial. The vial includes a body and a lid. The body of the vial has a base and a sidewall extending therefrom. The body defines an interior including a product space configured for housing at least one product and having an opening leading to the interior. The lid is configured to be attached to the sidewall by a hinge. The adapter includes a receiving portion having an opening configured to receive the body, and a base portion extending from the receiving portion. The base portion has a shelf portion proximate the opening. The shelf portion is configured to engage the lid of the vial when the lid is in a predetermined opened position in order to maintain the lid in the predetermined opened position with respect to the body.

A vial adaptor assembly, suitable for use with a vial containing a medicament and a syringe adaptor, which is in turn connectable to a syringe having a piston adapted for selectable displacement in a first direction for drawing fluid into the syringe and in a second direction for expelling fluid from the syringe, the vial adaptor assembly including: a vial connector for non-removable connection with the vial containing a medicament; a syringe adaptor connector for connection with the syringe adaptor; a pressure equalization chamber having a variable volume, which is sealed from the outside environment during use; a liquid pathway communicating between an interior of the vial containing the medicament and an interior of the syringe when the syringe adaptor is connected to the syringe adaptor connector and the syringe is connected to the syringe adaptor and the vial connector is connected to the vial containing the medicament; and a venting pathway communicating between the interior of the vial containing the medicament and an interior of the pressure equalization chamber, when the vial connector is connected to the vial containing the medicament, wherein the pressure equalization chamber and the venting pathway are mutually configured such that, when the syringe adaptor is connected to the syringe adaptor connector and the syringe is connected to the syringe adaptor and the vial connector is connected to the vial containing the medicament, substantially all of any of the medicament that becomes located within the pressure equalization chamber is removed therefrom via the venting pathway and returned to the interior of the vial by displacement of the piston of the syringe in the first direction.

The embodiments relate to improved skin quality, health and appearance using a new delivery method and certain bioactive compositions and formulations. The system incorporates microneedle delivery technology with unique compositions and formulations. Such development allows for the pursuit of personalized medicine, or treatment delivery that can expand to remote controlled environment, immediate compounding and ultimate personalization with a state of the art longitudinal data predictive analytics. Certain formulations described herein are unique, combinatory and synergistic. Secured by high-tech proprietary system, there are unlimited potentials using AQT technology including but not limited to 3-D printing of a biodegradable micro chips that can be delivered via injection, AQT or any other possible route.

A vacuum controlled liquid delivery system, including a primary chamber; a manifold assembly affixed to the primary chamber, the manifold assembly comprising a feed line and an external pressure line; and a cap configured to reversibly engage the manifold assembly at one end and reversibly cap a syringe at another end, the cap comprising a septum and a porous plug, wherein when the cap is attached to the manifold assembly the feed line passes through the septum, and further wherein the porous plug seals upon contact with a liquid.

A containment system and assembly for the automated production of pharmaceutical or biotechnical articles is provided. The containment system has a housing within which there is an inner chamber having at least one through opening. One or more robots are installed in the chamber, which have a manipulating element on the pivotable arms, which can move within a pivot range. One or more process units are installed in the chamber for the production of the articles. The chamber includes a process space for the production of the articles and a tub-shaped base space for anchoring the feet of the robots to the side surfaces inside the base space. The manipulating element functions as a gripping and transportation device for inspecting the articles or article parts and/or for the production of the articles.

A fluid transfer device (10) includes a vial holder (23) configured to hold a vial (22). An actuator (40) is coupled to the vial holder (23) and can rotate the vial (22) between upright and inverted positions. A pump (positive or negative pressure) can pump contents out of the vial (22). Before pumping of the contents the actuator (40) rotates the vial (22) to the inverted position and after pumping of the contents the actuator (40) rotates the vial (22) to the upright position.

An assembly of the present invention is designed specifically for filling vaporizer cartridges, pods, and other personal vaporizer systems with high viscosity extracts (oils). The assembly includes three main components such as the syringe station, the control box, and foot pedal. The control box includes the software to operate the assembly. The control box has controls for temperature and air pressure (for purging the vessel). The foot pedal operates the syringe for filling cartridges. The syringe station consists of a heated vessel, and a heated pneumatically operated syringe. The syringe system can be used in this configuration and can also be used as part of a larger, fully automated filling machine without limiting the scope of the present invention. The syringe system works well with viscous liquids.

A method for improving the efficiency of a pharmaceutical filling line by running the filling line at an increased throughput rate is disclosed. The method involves using glass vials that have been strengthened and coated to reduce the coefficient of friction of the outer surface of the vials with a pharmaceutical filling line set at a rate greater than or equal to 600 vials per minute and miming in an efficiency of at least 70%. In other embodiments of the invention, the pharmaceutical filling line may also be provided with a polymer chemical coating at points of contact with the glass vials, thereby further reducing the friction between the vials and the points of contact and the effects of impact of the vials with contact points of the pharmaceutical filling line.

A filling device for dosed filling of a product from a product storage container into product dose receiving containers provided in a disposable isolator so to be protected against contamination. The device includes means for holding the product storage container together with the contents outside of the disposable isolator. The device includes a controllable product removal device for a dosed removal of the product from the product storage container. The device includes a product dispensing device for the dosed dispensing of the product to the product dose receiving containers. The device includes a line assembly interconnecting the product storage container and the product dispensing device to conduct the product to the product dispensing device. The device includes at least one ultrasonic flowmeter outside of the disposable isolator fixed to the outside of the line assembly to detect the flow rate. The device includes a controller for measuring the product dose.

A sealed pharmaceutical container comprises a shoulder, a neck extending from the shoulder, and a flange extending from the neck. The flange comprises an outer surface extending from the underside surface and a contact surface extending between the outer surface and an inner surface defining an opening in the sealed pharmaceutical container. The contact surface comprises an outer peripheral edge disposed proximate to the outer surface of the flange. The sealed pharmaceutical container comprises a sealing assembly comprising a stopper extending over the contact surface of the flange and covering the opening, and a cap securing the stopper to the flange. The stopper comprises a sealing surface that is secured in contact with the contact surface of the flange to form a seal between the flange and the stopper. An outer peripheral edge of the sealing surface is disposed at or radially inward of the outer peripheral edge.