A system and method for conveying a sterilizing fluid to a filling machine includes a refilling tank for containing the sterilizing fluid and from which the sterilizing fluid is drawn, a spray tank fluidly connected to the refilling tank for receiving the sterilizing fluid from the refilling tank and conveying the sterilizing fluid to the filling machine, and a fluid line connecting the refilling tank to the spray tank. A vacuum generator is fluidly connected to the spray tank via a vacuum line and configured to generate a vacuum in the spray tank, such that the vacuum causes sterilizing fluid to be drawn from the refilling tank and into the spray tank.

A sterile filling unit, of a basic container with contents that can be distributed in a fluid form and that is originally located in a source container in a sterile manner, includes a sterile chamber with at least one sterile entry port and/or outlet; a sterile fluid transfer and filling line with an intake and an outlet, such that for a filling stage the line passes through the wall of the sterile chamber in a sterile manner, with the intake located outside of the sterile chamber in sterile fluid communication with the source container, with the filling element at the outlet located inside the sterile chamber and positioned to be operating; and a unit that can introduce the disposable internal elements that, in a stage prior to the filling stage, were located outside of the sterile chamber, into the interior of the sterile chamber in a sterile manner.

A sterile filling unit, of a basic container with contents that can be distributed in a fluid form and that is originally located in a source container in a sterile manner, includes a sterile chamber with at least one sterile entry port and/or outlet; a sterile fluid transfer and filling line with an intake and an outlet, such that for a filling stage the line passes through the wall of the sterile chamber in a sterile manner, with the intake located outside of the sterile chamber in sterile fluid communication with the source container, with the filling element at the outlet located inside the sterile chamber and positioned to be operating; and a unit that can introduce the disposable internal elements that, in a stage prior to the filling stage, were located outside of the sterile chamber, into the interior of the sterile chamber in a sterile manner.

A fluid dispenser device including a body; a reservoir containing one or two doses of a fluid, the reservoir including a stopper that closes the reservoir in leaktight manner before actuation; a dispenser head that is provided with a dispenser orifice; and dispenser mechanism for dispensing at least a portion of the fluid through the dispenser orifice during actuation. The device further includes a needle having a tip that is adapted to pierce the stopper during actuation, the reservoir being filled with the fluid and being closed with the stopper under a vacuum, so that the residual volume of air present in the reservoir between the fluid and the stopper is substantially zero.

Methods, apparatuses and systems for sealed dimpled film packages. A vacuum box having apertures, a dimpled bottom film sheet is placed on the base plate and an item to be packaged can be placed on the bottom dimpled film sheet. A top film sheet in a clamp frame is heated to a processing temperature and lowered towards the item and dimpled bottom film sheet. Vacuum suction causes sealing of the clamped top film sheet against the package from the base to the perimeter extending at an angle more than 5 degrees. The top film sheet is pulled down using the vacuum suction into contact with the dimpled film sheet from the base perimeter on the dimpled film sheet outward toward the perimeter of the dimpled film sheet forming a seal.

A method of providing a plurality of filled product bags of sterile fluid includes positioning a bag assembly onto a filling machine. The bag assembly includes a tube, a filter assembly, bladders, and stems. A stem is attached to a bladder, forms a fluid passageway, fluidly connects to the tube, and provides fluid communication into the bladders. The method includes fluidly coupling an inlet of the filter assembly to a connection line in fluid communication with a fluid source, and filling the bag assembly with a fluid. Filling the bag assembly includes passing the fluid through the filter assembly, the fluid passageway, and into the bladder. The method includes sealing the fluid passageway at a location between the tube and the bladders. The method includes cutting the stem to form a partially filled product bag having the sealed passageway. The method includes performing an integrity test on the filter assembly.

An inventive vacuum storage container for long term storage of perishable and non-perishable items, incorporating a pump, power supply, controller, sensor, top cover, expandable seal, pressure sensor and base plate. The controller activates the pump based on signals from the sensor to maintain a vacuum state within an interior vacuum chamber formed by the top cover, expandable seal, and base plate. The container is configured to effectively maintain vacuum pressure by activating a pump when the lack of vacuum pressure is indicated.

An inventive vacuum storage container for long term storage of perishable and non-perishable items, incorporating a pump, power supply, controller, sensor, top cover, expandable seal, pressure sensor and base plate. The controller activates the pump based on signals from the sensor to maintain a vacuum state within an interior vacuum chamber formed by the top cover, expandable seal, and base plate. The container is configured to effectively maintain vacuum pressure by activating a pump when the lack of vacuum pressure is indicated.

The invention relates to an automatic pressing power device of a vacuum packaging machine, wherein the automatic pressing power device comprises main body, power plate and power airbag, wherein the power plate is connected with the main body through the power airbag and forms a telescopic closed cavity; the bottom of the main body is provided with an air nozzle communicated with the closed cavity. The automatic pressing power device provided by the invention does not need to tighten the upper cover artificially, and has the characteristics of simple structure, low cost, high structural stability, long service life and the like.

Methods of inserting a lubricant free stopper into a lubricant free syringe barrel or lubricant free cartridge tube is disclosed. The method includes (1) inserting a stopper with a sealing rib into a placement region of a vacuum chamber, (2) creating a seal between the vacuum chamber and a syringe barrel or a cartridge tube, (3) maneuvering the stopper into a proximal end of the syringe barrel or cartridge tube by a first differential pressure and/or an insertion rod, (4) maneuvering the stopper through the barrel by second differential pressure and/or an insertion rod, (5) optionally sealing a pressure sealing cap to the proximal end of the vacuum chamber, (6) removing the vacuum chamber, insertion rod, and, if present, the pressure sealing cap. The methods are lubricant free or substantially lubricant free. The vacuum chamber may be electropolished and/or extrude honed.