Stable aerosol solution formulations comprising glycopyrronium bromide are useful for administration to patients with COPD and other respiratory conditions.

Stable aerosol solution formulations comprising glycopyrronium bromide are useful for administration to patients with COPD and other respiratory conditions.

Stable aerosol solution formulations comprising glycopyrronium bromide are useful for administration to patients with COPD and other respiratory conditions.

Stable aerosol solution formulations comprising glycopyrronium bromide are useful for administration to patients with COPD and other respiratory conditions.

A propellant filling apparatus (10) comprising a filling booth (11) for receiving within it one or more containers for filling with a propellant; a propellant inlet (12) to the filling booth (11) that is capable of supplying propellant into one or more containers within the filling booth (11) from a propellant supply; an inert gas inlet (13) supplying inert gas from an inert gas supply (14) into the filling booth (11), a discharge outlet (16) from the filling booth (11); an extraction fan (17) that is capable of adjusting its fan speed to maintain the pressure of gas in the filling booth (11) to be lower than atmospheric pressure; and an oxygen detector (27) that is capable of detecting levels of oxygen in the filling booth (11) and triggering circulation of inert gas in the filling booth (11) when the level of oxygen in the filling booth (11) falls below an oxygen threshold level.

A propellant filling apparatus (10) comprising a filling booth (11) for receiving within it one or more containers for filling with a propellant; a propellant inlet (12) to the filling booth (11) that is capable of supplying propellant into one or more containers within the filling booth (11) from a propellant supply; an inert gas inlet (13) supplying inert gas from an inert gas supply (14) into the filling booth (11), a discharge outlet (16) from the filling booth (11); an extraction fan (17) that is capable of adjusting its fan speed to maintain the pressure of gas in the filling booth (11) to be lower than atmospheric pressure; and an oxygen detector (27) that is capable of detecting levels of oxygen in the filling booth (11) and triggering circulation of inert gas in the filling booth (11) when the level of oxygen in the filling booth (11) falls below an oxygen threshold level.

The invention comprises a shampoo apparatus and method of use thereof, comprising: (1) a pressurized container, a pressure in the container in a range of seventy to two hundred pounds per square inch and (2) a shampoo in the container, the shampoo comprising greater than five thousand parts per million carbon dioxide, where the shampoo optionally contains a detergent, zinc pyrrolidone carboxylic acid, and/or minoxidil. The carbon dioxide in the container is optionally added as a solid or a liquid and/or is chemically formed inside the container, such as from any of a carbonic acid, a bicarbonate, a bicarbonate salt, and/or a carbonate. The carbon dioxide solvates/makes soluble and aids removal of sebacic acid on the scalp.

The invention comprises a shampoo apparatus and method of use thereof, comprising: (1) a pressurized container, a pressure in the container in a range of seventy to two hundred pounds per square inch and (2) a shampoo in the container, the shampoo comprising greater than five thousand parts per million carbon dioxide, where the shampoo optionally contains a detergent, zinc pyrrolidone carboxylic acid, and/or minoxidil. The carbon dioxide in the container is optionally added as a solid or a liquid and/or is chemically formed inside the container, such as from any of a carbonic acid, a bicarbonate, a bicarbonate salt, and/or a carbonate. The carbon dioxide solvates/makes soluble and aids removal of sebacic acid on the scalp.

Method for manufacturing a pressurising device for a beverage container, wherein a gas container is provided having a filling opening, into which gas container an amount of dry ice is inserted through the filling opening, where after the filling opening is closed and the dry ice is allowed to sublimate.

The invention comprises a shampoo apparatus and method of use thereof, comprising: putting a shampoo and carbon dioxide into a container, at least a portion of the carbon dioxide comprising at least one of a solid form and a liquid form; sealing the container; warming the carbon dioxide by at least fifty degrees Fahrenheit to form a carbon dioxide gas, the carbon dioxide gas at least partially dissolved in the shampoo, the carbon dioxide gas comprising a concentration of one-half to ten percent of the shampoo by mass; and pressurizing the container to a pressure exceeding sixty pounds per square inch, such as where a headspace forms in the container, the headspace comprising the carbon dioxide at a concentration greater than one thousand parts per million, where the pressurized carbon dioxide yields a propulsive force, a foam expansion function, and a cleaning function.