A solvatochromic indicator for detecting the presence of a bacterial infection is disclosed. An indicator consisting of Beta vulgaris and further optionally comprising Curcuma longa, isopropyl alcohol, and any combination thereof, undergoes a detectable color change in the presence of an infection. Further provided are filaments treated with the solvatochromic indicator wherein the detectable color change of the indicator is based on the pH of the tissues with a bacterial infection.

A computer assisted orthopedic surgery system for soft tissue balancing and implant planning is provided. The system includes a three dimensional position tracking system, a robot, a display, and a computer. The computer is operatively in communication with the three dimensional position tracking system, the robot and the display. The computer includes a processor configured to acquire native gap data between a first bone and a second bone of a joint, simulate implant gap data between a first implant model on a first bone model of the first bone and a second implant model on a second bone model of the second bone of the joint based on an implant planning criteria to calculate a plurality of implant gap profiles, determine a best match of the plurality of implant gap profiles to the native gap profile to determine an optimized implant plan, and output the optimized implant plan.

The present invention relates to the field of medical monitoring, and in particular non-contact monitoring of one or more physiological parameters in a region of a patient during surgery. Systems, methods, and computer readable media are described for generating a pulsation field and/or a pulsation strength field of a region of interest (ROI) in a patient across a field of view of an image capture device, such as a video camera. The pulsation field and/or the pulsation strength field can be generated from changes in light intensities and/or colors of pixels in a video sequence captured by the image capture device. The pulsation field and/or the pulsation strength field can be combined with indocyanine green (ICG) information regarding ICG dye injected into the patient to identify sites where blood flow has decreased and/or ceased and that are at risk of hypoxia.

A ballistocardiography device comprises: a support for a person, a plurality of pressure or acceleration sensors each providing an analogue signal representative of a pressure or an acceleration measured at a point on the support or on the body of the person, a multiplexer (41) configured to receive a plurality of analogue signals from sensors and to output a signal successively representative of the input signals and an operational amplifier (52) having one input (57) connected to the output of the multiplexer and provided, on its other input, with a mixed filter comprising an analogue-to-digital converter (53) converting the signal coming out of the multiplexer into digital data, a digital filter (54) acting on the digital data and a digital-to-analogue converter (55) converting the filtered digital data into an analogue signal that is fed into the other input (58) of the operational amplifier.

Systems and methods are disclosed in which changes in the position and/or orientation of an anatomical structure or of a surgical tool can be measured quantitatively during surgery. In some embodiments, the systems and methods disclosed herein can make use of inertial motion sensors to determine a position or orientation of an instrument or anatomy at different times and to calculate changes between different positions or orientations. In other embodiments, such sensors can be utilized in conjunction with imaging devices to correlate sensor position with anatomical landmarks, thereby permitting determination of absolute angular orientation of a landmark. Such systems and methods can facilitate real-time tracking of progress during a variety of procedures, including, e.g., spinal deformity correction, etc.

A magnetometer-based metal detection device and methods of use are described. The device includes a proximal portion, a central body and a distal portion, and at least one magnetometer positioned within or on the distal portion. The at least one magnetometer includes at least one sensor capable of sensing a magnetic field in three orthogonal axes. Also described is a method of calibrating the device to achieve rotational invariance, and a method of determining a directionality or directional line along which a target metal object lies.

The present invention is directed generally to a method and apparatus for human brain neuroprotection during surgery. The invention includes use of a heart-lung machine to generate periodic rectangular pulsation of blood flow. The invention uses a non-invasive CA monitor to continuously record transient functions such as dynamic autoregulation functions of a human brain cerebrovascular autoregulation system and process the data to generate an alarm to indicate CA impairment and take steps to minimize the CA impairment event.

A system includes a display and a processor. The processor is configured to compute multiple forecasted local activation times (LATs) at different respective locations on cardiac tissue of a subject, by simulating a propagation of a physiological activation potential along the cardiac tissue with a particular portion of the cardiac tissue, which is currently conductive, being non-conductive. The processor is further configured to generate, based on the forecasted LATs, a forecasted electroanatomical map representing a forecasted state of the cardiac tissue following an ablation of the particular portion of the cardiac tissue, and to display the forecasted electroanatomical map on the display. Other embodiments are also described.

In general, devices, systems, and methods for fiducial identification and tracking are provided.

Systems and methods for monitoring and display of a hemodynamic status of a patient. Hemodynamic status may be monitored using, for example, a transducer, an adapter and one or more monitor devices. The adapter may be in communication with the transducer and the one or more monitor devices. The adapter can be configured to receive and process data from the transducer such as unprocessed physiological data. The adapter can be configured to transmit data to the monitor device(s) such as processed and/or unprocessed physiological data. The adapter can be configured to generate, and transmit to the monitor devices(s), user interface data for rendering interactive graphical user interfaces to display information such as physiological information relating to a hemodynamic status of the patient. The adapter can be configured to receive and process, from the monitor device(s) user commands or instructions to control an operation of the system or its components.