A dual-sided biomorphic polymer-based microelectrode array and method of fabricating the same. A measurement probe fabricated from a polymer consisting of two sides each with an array of paired recording sites for the measurement of molecules in an aqueous biological or chemical environment. Enzyme-based coatings are placed on microelectrodes of one measurement probe side specific to analytes of interest, and are coupled with a similar but non-functional protein matrix coating on the microelectrode on the opposite side to yield two distinct recording sites for subtraction of interferents, noise and non-Faradaic background current. Microelectrodes are arranged with variable spacing between each to match a variety of brain structures affording a biomorphic array allowing simultaneous recordings at multiple target depths and coordinates from one measurement probe system. The fabrication method uses photolithographic techniques where each dual-sided biomorphic polymer-based microelectrode array is cut out using lithography, allowing for multiple different or identical designs that can be simultaneously patterned on a single polymer wafer and improved microelectrode tip that is tapered for improved tissue penetration.

Provided is an endoluminal device system including: an elongated and flexible endoluminal device; a wire that is disposed in the endoluminal device; a first sensor that detects tension of the wire; a second sensor that detects displacement of the wire; a driving device capable of pulling the wire; and a processor. The processor is configured to: cause the driving device to execute a relaxing operation for relaxing the wire, acquire the tension and the displacement of the wire during the relaxing operation, which are detected by the first sensor and the second sensor, respectively, and adjust a control parameter of the endoluminal device based on a rate of change in the tension with respect to the displacement.

A device includes a power antenna and a data antenna, along with a switch operable to selectively connect the data antenna to data circuitry under various conditions. For example, the switch may be opened to decouple the data antenna when charging circuitry is receiving power through the power antenna, or under other conditions indicating that charging may be available or desired, thereby allowing for relatively unimpeded and efficient wireless charging of a device. The switch may be closed to enable use of the data antenna by data circuitry when wireless charging activity is not present, or when other conditions indicate that wireless data is available for the device.

An ophthalmic apparatus comprises a visible light illumination channel, which illuminates a retina of an eye of a patient under examination by visible light. A near-infrared illumination channel illuminates the retina of the eye of the patient under examination by near-infrared light. An imaging channel receives light from the retina of the eye illuminated by the visible light and/or the near-infrared light. A target channel outputs fixation image content to a patient whose eye is under the examination for fixation of a gaze direction of the patient. An alignment arrangement illuminates the anterior part of the eye and reflections therefrom are received by two of a fundus camera sensor and a first and second pupil camera sensors. A data processing unit determines an optimal positional alignment of the eye for imaging a fundus of the eye by a fundus camera sensor based on still image and/or video capture of the anterior part of the eye.

Particular embodiments include, by a computing device, receiving one or more wavefront elevation maps for a patient's eye and identifying one or more attributes of the one or more wavefront elevation maps corresponding to vitreous floaters. The one or more attributes may include localized spatial variation of the one or more wavefront elevation maps; temporal variation among a plurality of wavefront elevation maps; and depth information indicating scattering of light from within the vitreous of the patient's eye. A machine learning model may be trained and utilized to characterize vitreous floaters based on the one or more wavefront elevation maps and other patient data. The wavefront elevation maps may be measured using an aberrometer. The aberrometer may be integrated with a LIDAR system to estimate depth of scattered light. A common laser light source may be used for both the aberrometer and the LIDAR system.

The present invention relates to a sensor arrangement comprising a support substrate and at least two microwave antennas fixedly arranged in or on said support substrate, each microwave antenna being separated from all other microwave antennas by a band-stop structure configured to cancel direct coupling between the microwave antennas, said sensor arrangement further comprising microwave signal transmission paths configured to transmit microwave signals to or from said microwave antennas. The invention also relates to a system comprising such a sensor arrangement and a method for non-invasive assessment of a property of subdermal tissue in a subject.

Embodiments herein relate to ear-wearable stress and anxiety monitoring systems, devices and methods. Embodiments herein further relate to ear-wearable systems and devices that can detect and take actions to alleviate device wearer's stress and anxiety. In an embodiment an ear-wearable stress and/or anxiety monitoring system is included having a control circuit, a microphone, and a sensor package that can include a motion sensor. The ear-wearable system is configured to evaluate data from at least one of the microphone and the sensor package and classify a stress level of a device wearer using a machine learning classification model and periodically update the machine learning classification model based on indicators of stress experienced by the device wearer.

A diaphragm imaging device includes at least one electronic processor programmed to perform a diaphragm imaging method including receiving ultrasound imaging data of a diaphragm of a patient, the ultrasound imaging data being acquired by an associated ultrasound imaging probe with the probe at a plurality of different observable probe angles (?.sub.obs); for each observable probe angle, determining a corresponding apparent thickness (d.sub.I) of the diaphragm of the patient from the received ultrasound data acquired at that observable probe angle; and estimating a thickness (d.sub.D) of the diaphragm of the patient based at least on the apparent thicknesses (d.sub.I).

Embodiments of the application relate to the technical field of Optical Coherence Tomography (OCT) devices, and disclose a detection method and system directly applying noninvasive OCT to an endometrium, and a detection device. The method includes: inserting an OCT probe into a uterine cavity through a cervical orifice until reaching a fundus of a uterus; pulling back the OCT probe, and starting an image acquisition apparatus at the same time to obtain a plurality of OCT images; and dividing the plurality of OCT images into four areas, namely a uterine fundus area, a uterine upper section area, a uterine lower section area, and a cervical area, each area having one or more OCT images, and analyzing the OCT image of each area. By implementing the embodiments of the application, each area may be analyzed according to the OCT image, a human body cannot be injured, and the detection is accurate.

A weightbearing simulation assembly, includes a substrate having a mounting surface, the substrate further including a first section and second section hingedly coupled together such that the first section and second section are foldable relative one another. A subject support is disposed on a first section of the mounting surface, and a pedal assembly is disposed on a second section of the mounting surface. The pedal assembly is spaced apart from the subject support by a distance, and includes a contact plate that receives a compressive force from a subject, measures the compressive force, and provides an indication that the compressive force corresponds to a weightbearing condition of the subject.