Disclosed herein is a medical device. The medical device includes an outer tubular member and an inner tubular member. The outer tubular member has a distal end, an open window disposed at the distal end, and one or more dimples. The inner tubular member has a distal tip and one or more axial grooves. The inner tubular member is configured to be received within the outer tubular member. The one or more axial grooves and the one or more dimples are configured to align the distal tip of the inner tubular member with the open window of the outer tubular member. The open window of the outer tubular member and the distal tip of the inner tubular member are configured to cut tissue.

A system for the characterization of vital or reconstituted tissues, in particular skin appendages, includes a plurality of sources of electromagnetic radiation to be spatially oriented and to irradiate according to a selected angle of incidence a sample of vital or reconstituted tissue having a series of filaments of a person that are homogenous in structural type, at least one image acquisition device for receiving a reflected and/or dispersed radiation from the sample, or a fluorescence radiation emitted by the sample, and an image processing unit configured to process reflection, and/or dispersion and/or fluorescence images, and to classify examined tissue to compare the value of at least one parameter selected from gloss, dimensions, colour intensity, contour of the filaments of the sample with a database of parameters of classes of predetermined vital or reconstituted tissues, and/or to compare the value of the at least one parameter with a database of historic values of parameters of the tissue.

An applicator for an analyte monitoring device may include an actuatable housing having a body defining a cavity therein and having a distal opening and a side opening. A cuff and a shuttle are received within the cavity and are separately translatable relative to the housing body. A base may removable engage the housing body at the distal opening. The housing body, the cuff, the shuttle, and/or the base may be engaged with one another with one or more releasable coupling features. The base may be removed from an engagement with the housing body, causing the cuff and the shuttle to be aligned and positioned in a configuration in which the analyte monitoring device, held by the shuttle, is ready for insertion into the skin.

Provided herein are systems, devices, and methods to facilitate imaging an infant using a magnetic resonance imaging (MRI) device. A system for facilitating imaging an infant using an MRI device is provided herein, the system comprising a radio frequency (RF) coil assembly configured to be coupled to the MRI device and comprising a first RF coil configured to transmit RF signals during MRI and/or be responsive to MR signals generated during MRI and a helmet for supporting at least a portion of the infant's head, and an infant support to support at least a portion of the infant's body and configured to be coupled to the RF coil assembly. Further provided is an apparatus for coupling an infant support to an MRI device.

Systems and methods for processing sensor data are provided. In some embodiments, systems and methods are provided for calibration of a continuous analyte sensor. In some embodiments, systems and methods are provided for classification of a level of noise on a sensor signal. In some embodiments, systems and methods are provided for determining a rate of change for analyte concentration based on a continuous sensor signal. In some embodiments, systems and methods for alerting or alarming a patient based on prediction of glucose concentration are provided.

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

The present invention is related to electrode belts and, more particularly, to electrode belts used to obtain signals from electrical impedance tomography. The electrode belt for acquiring signals of electrical impedance tomography comprises at least one module, in which each module comprises at least two electrodes, wherein the center of each electrode is placed at a predetermined distance in relation to the center of at least one other adjacent electrode.

Aspects of articulating devices and methods are disclosed. An exemplary articulating device may comprise an interior core with a reinforcing extending along a central axis, an exterior layer bonded to the interior core by an interface, and a lumen extending through the exterior layer, exterior of the reinforcing element, and parallel to the central axis. A steering wire may be moveable in the lumen to articulate a distal end of the device relative to the central axis in response to a force applied to the steering wire. Related methods of manufacturing an articulating device are also described.

A surgical access device includes a cannula body and a fixation mechanism. The cannula body includes a housing, and an elongated portion extending distally from the housing and defining a longitudinal axis. The fixation mechanism includes a flange, a fixation sleeve, and a proximal sleeve. The flange is rotatable about the longitudinal axis. The fixation sleeve extends distally from the flange and radially surrounds a portion of the elongated portion of the cannula body. The proximal sleeve extends distally from the flange and radially surrounds a proximal portion of the fixation sleeve. Rotation of the flange causes a radially-expandable portion of the fixation sleeve to move between a first position defining a first gap between the radially-expandable portion and the elongated portion, and a second position defining a second, greater, gap between the radially-expandable portion and the elongated portion.

A system for detecting presence of coronavirus in a subject, the system including a first pad for placing a first hand, the pad including a contact to measure conductance of the subject's body, a conductance meter connected to the contact, a second pad for placing a second hand, a source of electromagnetic radiation for irradiating the second pad.

A system for detecting presence of coronavirus in a subject, the system including a chip with a plurality of wires disposed on or in the chip, a conductance meter arranged to measure conductance between the wires, and biological material associated with the coronavirus disposed on or in the chip.

Related apparatus and methods are also described.