A dispenser (1) for liquids includes a reservoir (100) defining a volume (V100) for housing a liquid (150); a delivery tube (200) with a first end (201) attached to the reservoir, and a second end (202) distal from the reservoir, the delivery tube including a passage (203) in fluid communication with the volume of the reservoir and extending away from the reservoir; an applicator element (300) including an applicator tip (320) and a base (310) attached to the second end of the delivery tube, the applicator tip having a plurality of fingers (322) extending away from the base to a distal end of the applicator element distal from the delivery tube; and a removable seal (340), wherein removal of the removable seal creates an opening in the passage at a location upstream of the applicator tip and a fluid distribution channel between the fingers.

The invention relates to a method and to a device for filling a medical packaging formed as a pouch. Preferably, the packaging is filled with liquid via a port, wherein the port is aerated with a protective gas, such as nitrogen, for example, during filling According to the invention, prior to filling with liquid, the packaging is filled with an inert gas, such as nitrogen, for example, which then provides the headspace of the filled and closed pouch. This results in a particularly low oxygen content in the headspace of the pouch.

A blow molding, filling and closing process and container product produced accordingly, in particular an ampoule product.

A blow molding, filling and closing process for producing a filled and closed container product that can be stored as well, in particular in the form of an ampoule product which is formed from a plastic material and has a single-layer container wall or ampoule wall and which, during initial use, permits the withdrawal, in particular for an oral use of the product content, by opening at least one withdrawal opening for withdrawal purposes, is characterized in that plastic materials suitable for the process are selected which are tasteless and/or odorless or essentially tasteless and/or odorless in interaction with the contents of the container before and during use and which retain this tastelessness and/or odorlessness even after prolonged storage.

A blow molding, filling and closing process and container product produced accordingly, in particular an ampoule product.

A blow molding, filling and closing process for producing a filled and closed container product that can be stored as well, in particular in the form of an ampoule product which is formed from a plastic material and has a single-layer container wall or ampoule wall and which, during initial use, permits the withdrawal, in particular for an oral use of the product content, by opening at least one withdrawal opening for withdrawal purposes, is characterized in that plastic materials suitable for the process are selected which are tasteless and/or odorless or essentially tasteless and/or odorless in interaction with the contents of the container before and during use and which retain this tastelessness and/or odorlessness even after prolonged storage.

An arrangement for monitoring a freeze drying process includes product condition sensors for product condition measurement within product vials. The product condition sensors are bimetal junctions deposited on a substrate using an ink jet printing process. The substrate may be a flexible film applied to an interior surface of the product vial, or may be the vial surface itself. The bimetal junction may be printed using a roll-roll inkjet printing process with metallic nanoparticle inks. Multiple closely-spaced bi-metal junctions are provided in each measurement vial. Data from the sensors is transmitted to a data collection point via short range wireless digital communications. The location of a sublimation front may be calculated for each measured vial, and the freeze drying process may be controlled using the data.

An arrangement for monitoring a freeze drying process includes product condition sensors for product condition measurement within product vials. The product condition sensors are bimetal junctions deposited on a substrate using an ink jet printing process. The substrate may be a flexible film applied to an interior surface of the product vial, or may be the vial surface itself. The bimetal junction may be printed using a roll-roll inkjet printing process with metallic nanoparticle inks. Multiple closely-spaced bi-metal junctions are provided in each measurement vial. Data from the sensors is transmitted to a data collection point via short range wireless digital communications. The location of a sublimation front may be calculated for each measured vial, and the freeze drying process may be controlled using the data.

A liquid ant bait pack having a primary bait well and a plurality of feeding reservoirs for holding liquid bait is provided in which the walls of the feeding reservoirs as well as the primary bait well are sloped to facilitate ant access to the liquid bait held therein while reducing the risk of the ants falling into the bait and drowning. Ant access is further facilitated by dry platform areas positioned between the reservoirs. The inclusion of multiple feeding reservoirs, the bait well and the dry platform areas provides an increased area over which ants can simultaneously access the bait. The entrance to the bait pack is sealed during manufacture and then readily opened by the consumer using a tear-off tab that can removed without the need for any tools.

A method for producing glass vials, in particular pharmaceutical vials or pharmaceutical ampoules, from a glass tube is provided, the method including the following steps: (a) rotating the glass tube about a longitudinal axis thereof; (b) locally heating the glass tube from one side by means of at least one burner to at least the softening temperature of the glass; (c) reducing the diameter by pressing at least one forming body laterally against the heated region; and (d) separating the glass tube by means of a burner. A glass vial produced in such a way releases a reduced amount of alkali in accordance with ISO 4802 and has a decreased delamination tendency. Furthermore, in the hot-formed peripheral region, the alkali content is only slightly reduced when compared with the alkali content in the glass interior.

A method for producing glass vials, in particular pharmaceutical vials or pharmaceutical ampoules, from a glass tube is provided, the method including the following steps: (a) rotating the glass tube about a longitudinal axis thereof; (b) locally heating the glass tube from one side by means of at least one burner to at least the softening temperature of the glass; (c) reducing the diameter by pressing at least one forming body laterally against the heated region; and (d) separating the glass tube by means of a burner. A glass vial produced in such a way releases a reduced amount of alkali in accordance with ISO 4802 and has a decreased delamination tendency. Furthermore, in the hot-formed peripheral region, the alkali content is only slightly reduced when compared with the alkali content in the glass interior.

Embodiments of the present disclosure are directed to coated glass articles which reduce glass particle formation caused by glass to glass contact in pharmaceutical glass filling lines.