This invention relates the use of cortisol blockers (glucocorticoid receptor [GR] antagonists) for the treating or preventing treatment resistant prostate cancer, treating or preventing neoplasia, and treating or preventing infection related to acute or chronic injury or disease.

The present invention aims to provide a heat-shrinkable polyester film that contains a PET bottle recycled raw material but that has sufficient shrinkability, a low shrinkage stress, and a high solvent adhesion strength. The present invention provides a heat shrinkable polyester film, wherein a polyester of the polyester film contains recycled raw material from a PET bottle and an acid component of the polyester comprises isophthalic acid, and the film satisfies a shrinkage rate in a main shrinkage direction, a maximum shrinkage stress in the main shrinkage direction, a melting heat amount, a solvent adhesion strength, and a limiting viscosity.

A heat shrinkable stretched multilayer film for skin packaging comprising a crosslinked resin layer, a gas barrier resin layer, and a heat sealing resin layer sequentially arranged in this order from the outer side, and having dry thermal shrinkage rate of 10 to 55% in each of the machine direction (MD) and of the transverse direction (TD) at 120 C., and tensile elongation at break of 190% or greater in the machine direction at 120 C.

A package for a particulate laundry scent additive.

A combined wine glass and wine bottle package includes a wine glass constructed from molded plastic with an upper shell-shaped body defining an upwardly narrowing tapered flume of generally uniform thickness and a contoured lower base defining an annular moat surrounding a central punt. A wine bottle is sized to fit substantially into the wine glass in an inverted orientation with a removable bottle cap nested within the central punt, and with an upper rim of the wine bottle snap-fitted into a shallow groove formed in the wine bottle near a lower end thereof. This entire package is sterile-wrapped in a sealed shrink-wrap plastic or the like. The package can be opened when desired to permit removal of the wine bottle from the wine glass, following by bottle opening and pouring of the contents into the wine glass.

A method for treating open cut edges of a packaging sleeve (S), blank or web material of a packaging material rolled up into a roll, in particular a composite cardboard/plastics material, by applying or introducing a disinfectant-containing treatment agent to or into the outer region of the cut edges. To provide a particularly resource-efficient composite packaging and a production method required for this purpose, it is proposed that at least some of the treatment agent is not applied directly to the cut edges, but that a load carrier (9) is loaded, which load carrier absorbs the treatment agent so that an actively sterilizing atmosphere which is created then acts on the open cut edges of the packaging sleeve (S), blank or web material and performs the desired sterilization. The invention also relates to a packaging material, to a combipack produced therefrom and to a container for receiving the packaging material.

A method of individually packaging a single-use disposable diaper for use in intimate absorption of body fluid includes compressing a single-use disposable diaper for use in intimate absorption of body fluid from a first condition to a second, compressed condition, and retaining the single-use disposable diaper in the second, compressed condition with a pressure differential that acts upon a substantially flexible, substantially air impermeable material to maintain the single-use disposable diaper in the compressed condition. The pressure differential is created by locating the single-use disposable diaper in an interior space of a substantially air impermeable, substantially flexible material, creating a negative pressure within the interior space, and hermetically sealing the single-use disposable diaper at the negative pressure within the flexible material. The single-use disposable diaper is the only single-use disposable diaper contained within the hermetically sealed substantially air impermeable, substantially flexible material.

A heat-shrinkable packaging article has one or more tear initiators for initiating a manual tear that can be propagated to open a package and allow a product to be readily removed therefrom, without the use of a knife or scissors or any other implement. The tear initiators are present in a skirt and/or header of the article. The skirt and/or header has a first side and a second side. In one embodiment, some or all of the first side of the skirt and/or header can be heatset in order to reduce the shrink and curling of the skirt and/or header. This improves identification and utilization of the tear initiators by a consumer upon shrinking the packaging article around the product. In another embodiment, the skirt and/or header has a plurality of pairs of tear initiators to allow portions of the package to be torn off to expose a portion of the product that can then be sliced off while the remainder of the packaged product remains covered by a remainder of the film.

A sterile filter module/dialyzer packaging including a filter module, preferably a dialyzer, sterile-packaged in a primary packaging. The filter module having an essentially cylindrical central section and a filter module connection formed at the end of the central section. The primary packaging is a blister packaging with a plastic molded part as a lower section forming a receiving compartment for the filter module and a soft upper foil which, with the lower section, closes the receiving compartment for the filter module. The upper foil is fixed onto the lower section so as to be hermetically sealed and the filter module is fixed at least in sections by means of form fit.

A heat-shrinkable bag has a means for initiating a manual tear that can be propagated to open the bag and allow a product to be readily removed therefrom, without the use of a knife or scissors or any other implement. The bag is made from a heat-shrinkable multilayer film having a Peak Load Impact Strength of at least 50 Newtons per mil. The means for initiating tearing results in a first tear in the first side of the bag, and a second tear in the second side of the bag. The first tear and the second tear are each capable of being manually propagated through a heat seal and across the bag, or down the length of the bag, with the tear being capable of being manually propagated through and to an opposite bag edge, so that the product inside a package can be readily removed from the bag. A process for making a package and manually opening the package, comprises placing a product inside the bag, sealing the bag closed, shrinking the film around the product, manually initiating and manually propagating the first and second tears, and readily removing the product from the bag.