The present invention provides a crystallographic orientation structured titanium alloy dental implant and manufacturing method thereof. The technique of modifying the surface structure (Ti/TiO.sub.2, amorphous) of the titanium alloy dental implant to form a [Ti/TiO.sub.2 anatase (215)] crystallographic orientation structure is applied in osseointegration field for improving activity of osteocyte, shortening the identification period of initial growth of osteocyte, accelerating the integration of human bone and the calcification of osteocyte tissue, with the advantage of healing wound fast, therefore being suitable for clinical treatment of dental implant surgery. The structure is relatively stable, uneasy to be worn and damage proof, not affected by the surface roughness, and assures the hydrophilicity of the adherence capacity of osteocyte. The structure features a specific crystal grains arrangement direction (crystallographic orientation) so as to increase cell activity, hydrophilicity, and biocompatibility.

A biomimetic composite material includes a bioactive cement material, an autologous dentin matrix, and an inorganic nano-reinforcement material. A dental implant includes a body including a biomimetic composite material, wherein the biomimetic composite material includes a bioactive cement material, an autologous dentin matrix, and an inorganic nano-reinforcement material.

A medical that is implantable into a human or animal body or being an augmentation device for strengthening human or animal hard tissue for subsequent implantation of a separate implant. The device includes a sheath element suitable of being brought into contact, during a surgical operation, with live hard tissue and/or with hard tissue replacement material. The sheath element has a, for example, generally elongate shape and a longitudinal bore defining a longitudinal opening reaching from a proximal end of the sheath element into a distal direction, and a plurality of holes in a wall of the opening. Further, the device includes a liquefiable element that is insertable or inserted in the longitudinal opening and at least partly liquefiable by the impact of energy impinging from the proximal side.

The present invention provides a coloring solution for zirconia, which, when used on zirconia before firing of the zirconia, causes the zirconia to exhibit only a slight color difference before and after the firing and thus enables accurate prediction of the post-firing color tone of the zirconia. The present invention relates to a coloring solution for zirconia, comprising: a coloring agent (A) that is decolorized after firing of zirconia; and a metal ion solution (B), wherein, when zirconia is colored with the coloring solution and then subjected to firing, the color difference of the zirconia before and after the firing satisfies ΔL*≤5.8, Δa*≤2.4, and Δb*≤4.3.

A method is provided for producing a dental prosthesis from a blank using a CAD/CAM device, wherein the blank consists partially of base material and partially of tooth material, and a boundary surface between these materials is formed as a wave, the wave crests and wave valleys of which alternate with each other along the outer periphery of the blank. The apex of each wave crest extends substantially radially with respect to the blank. The CAD/CAM device fixes the position of a retention part, which serves to fasten the prosthesis to the alveolar crest of a patient, in particular of an external telescope, of a cover of a bar, or of an abutment in the prosthesis in such a way that it passes through the boundary surface. The retention part is fastened by means of gluing or incorporation by polymerisation.

A bone implant for at least partial insertion into a bone and/or cartilage. The bone implant is at least partially formed of a metal alloy of at least about 90 wt. % of a solid solution or a rhenium and molybdenum alloy.

A dental prosthesis system includes at least one first and second dental prosthetic care part (1, 2) made of zirconium dioxide (ZrO.sub.2). Each of the two care parts has corner radii (R1, R11, R2, R22, R3, R26, R12, R13), and the corner radii (R1, R11, R2, R22, R3, R26, R12, R13) correspond to one another, wherein the first care part (1) is operatively connected to the second care part (2). At least one of the corner radii (R1, R11, R2, R22, R3) of the first dental prosthetic care part and/or the second dental prosthetic care part (R26, R12, R13) has a value of less than 0.1 mm, and the at least one corner radius (R1, R11, R2, R22, R3, R26, R12, R13) is produced by a material removal process using a laser method and/or by a machining process using a drill or a milling cutter made of full diamond.

The present invention provides a trabecular porous tantalum dental implant and a preparation method thereof. The trabecular porous tantalum dental implant provided by the present invention has a cylindrical structure, and sequentially includes a top functional area, a middle functional area and a bottom functional area from top to bottom. The top functional area has a compact structure. The middle functional area has a porous bionic trabecular structure. The bottom functional area has a compact structure. The trabecular porous tantalum dental implant is integrally prepared through an additive manufacturing technology by using pure tantalum or medical tantalum alloy powder as a raw material. The trabecular porous tantalum dental implant provided by the present invention has a high friction force, strength and modulus close to those of human bones, an excellent bone ingrowth effect, high implantation stability and long service life.

The invention relates to a method of producing an implantable collagen-containing medical device comprising the step of coating said collagen-containing medical device with metal microparticles and/or metal nanoparticles, wherein said step of coating said collagen-containing medical device is by sonication such that the collagen-containing medical device has anti-bacterial and anti-inflammatory properties on implantation compared to the medical device not coated with metal microparticles and/or metal nanoparticles.

A method for producing an implant blank (100), in particular a dental implant blank from a starting body, said implant blank (100) comprising at least one first area, which is a surface area (102), and a second area, which is a core area (101), wherein the surface area (102) has at least one bioactive surface material (502) and extends from at least one first surface (103) in the direction of the core area (101), and the core area (101) has at least one carrier material that can be subjected to mechanical load. The starting body has a porosity for controlling a targeted distribution of the bioactive surface material (502) within the starting body and is loaded with a solution (500) of the bioactive surface material (502) in a first step, which is a loading step. In a second step, which is a distribution control step, the distribution of the bioactive surface material (502) within the starting body is controlled such that the solution (500) has a higher concentration within the surface area (102) than within the core area (101), the control being effected by regulating one or more environmental parameters in a closed environment (200), in particular by regulating the humidity and/or the pressure and/or the temperature.