Cartilage support implants for nasal valve support and delivery systems are described. The cartilage support implant can include one or more elongate bodies comprising one or more anchors. The cartilage support implant can be designed to be a permanent implant extending along the midline of a patient's nose, from the nasal bone to the lower lateral cartilage. Methods of placing the cartilage support implant and retrieving the cartilage support implant are also described.

An endoprosthesis has an expanded state and an unexpanded state, the endoprosthesis includes a stent, wherein the stent has a first end, a second end, an inner surface defining a lumen, an outer surface, and a thickness defined between the inner surface and the outer surface; and a stent end covering disposed at one of the first and second ends, the stent end covering including a polymeric coating that includes a base and a plurality of protrusions, the base including a first major surface facing the outer surface of the stent, the base further including a second major surface from which each of the plurality of protrusions extends outwardly, the first major surface opposing the second major surface, wherein the protrusions are arranged in a micropattern. Methods of making and using an endoprosthesis are provided.

A coil device for treating a heart valve includes a wire with a distal end and a proximal end with a cloth configured to promote ingrowth of tissue into the cloth covering at least a portion of the wire. The wire is formed at least partially from a memory metal that is pre-shaped to assume a helical coil shape with a diameter designed to provide a constricting force on a ventricle wall of a heart when the coil device is woven behind tissue features of trabeculae carneae associated with the ventricle wall.

An implant for the cardiovascular system is provided, the implant is insertable into an organ and includes a body structure configured to be disposed inside an organ; and an electret coating disposed on the body structure; wherein the electret coating includes a negative charge such that a negative electrostatic field is formed in proximity of the body structure, the charge is such that the negative electrostatic field corresponds to a positive electrostatic field formed by a damaged tissue of the organ.

Methods of delivering a prosthetic aortic heart valve are disclosed. The disclosed methods include loading a prosthetic aortic valve in a collapsed configuration into a delivery sheath so that a selected point on the prosthetic valve is rotationally aligned relative to a long axis of the delivery sheath with a selected radiopaque marker on the delivery sheath, while under fluoroscopic imaging, rotating the delivery sheath about its long axis to align a selected radiopaque marker on the delivery sheath with the selected point on the native aortic valve in a fluoroscopic imaging plane, thereby establishing a desired orientation of the prosthetic aortic valve with respect to the native aortic valve in which the prosthetic valve commissures are rotationally aligned with commissures of the native aortic valve, further advancing the delivery sheath along its long axis until the prosthetic aortic valve is disposed inside the native aortic valve, and deploying the prosthetic aortic valve into an implanted state inside the native aortic valve with the prosthetic aortic valve aligned in the desired orientation with respect to the native aortic valve.

The present disclosure pertains to membranous tissue grafts comprising one or more pre-made attachment points. The one or more pre-made attachment points may include pre-made markings and/or pre-made suture holes. The membranous tissue grafts can be in the form of a tube. The membranous tissue grafts can also be rectangular in shape and can be used in a nerve repair by wrapping the severed or damaged nerve. In some embodiments, the membranous tissue grafts are suitable for repairing severed nerves that have a short gap or no gap with a gap of less than 5 mm between the severed stumps. Accordingly, methods are provided for repairing a damaged or severed nerve by implanting the membranous tissue grafts on to the damaged or severed nerve.

A method for placing an implant on a patient in a robotic surgical procedure using a robotic system. During the robotic surgical procedure, a navigation system tracks the patient. The navigation system also provides information to the robotic system to guide movement of a cutting tool to remove material from the patient such that a cut surface is created to receive the implant. The implant is then robotically placed on the cut surface.

Disclosed are devices and methods for treatment of eye disease such as glaucoma. Implants are described herein that create a flow field, such as between the anterior chamber and either the supraciliary space or suprachoroidal space. In addition, the implant can be treated with one or more treatments, including plasma treatments, for creating a variety of surface features and characteristics. Some of the surface features and characteristics can assist in controlling tissue responses to the implanted implant, including promoting or preventing tissue proliferation.

A method for structuring a surface of an implant (100) made from a plastic material by means of a counter-body (200) comprises the following steps: providing (S110) of a counter-body (200) including a surface (210); forming (S120) of a first surface structure (212) on the surface (210) of the counter-body, wherein a first surface structure (212) comprises a non-regular, randomly distributed pattern; and forming (S130) of a second surface structure (112) on the implant (100) by using the counter-body (200), wherein the second surface structure and the first surface structure (212) are complementary to each other.

The present disclosure relates generally to stents, systems, and methods for gastrointestinal treatment. In some embodiments, a stent may include a tubular scaffold having a first end opposite a second end, wherein a lumen extends between the first and second ends. The tubular scaffold may include a flared section and a medial section extending from the flared section, wherein a first diameter of the flared section is greater than a second diameter of the medial section. The stent may further include a liner extending partially along a surface of the tubular scaffold, wherein the liner is spaced from an anchoring region of the flared section to promote tissue ingrowth with the flared section.