A targeted temperature management (TTM) system for providing a TTM fluid including a thermal pad is disclosed. The pad includes a fluid delivery conduit and a fluid return conduit extending continuously from the pad to the TTM module. Valves may be included in line with fluid delivery and fluid return conduits. The thermal pads include one or more conduit retention devices for binding the fluid conduits together. Methods of using the system are disclosed and include disposing a thermal pad in a storage configuring where the fluid conduits are wound together to form a coil, winding the fluid conduits together to form a coil, binding the windings together with a conduit retention device, and placing the coil underneath a stretchable band of the thermal pad.

Disclosed are fluid delivery lines (“FDLs”) of systems, pads, and methods for targeted temperature management. A system can include a control module, a primary FDL, a secondary FDL, and one or more pads for placement on one or more portions of a patient's body, respectively. The primary FDL can be configured to convey a temperature-controlled fluid as a supply fluid from a hydraulic system of the control module and convey a return fluid back to the hydraulic system. Each pad of the one-or-more pads can include a multilayered pad body including a conduit layer configured to convey the supply fluid therethrough. The secondary FDL can be configured to convey the supply fluid from the primary FDL and convey the return fluid back to the primary FDL. The secondary FDL can include a pair of piercing tips configured to pierce the primary tubing for fluidly connecting the primary and secondary FDLs.

Disclosed herein is a system, apparatus and method directed to an orientable and resizable targeted temperature management (TTM) pad. The system, apparatus and method pertain to a medical pad for exchanging thermal energy between a TTM fluid and a patient. The pad can include a fluid containing layer for containing the TTM fluid, a patient contact surface to facilitate thermal energy exchange with the patient, a central trunk structure, and at least two wings branching from the central trunk structure. The fluid containing layer can be configured for circulating the TTM fluid within the fluid containing layer. The patient contact surface can be disposed at least on part of the central trunk structure. The at least two wings can be configured to be wrapped around a portion of a body of the patient. The central trunk structure may be positioned beneath the patient. The wings may be trimmed, reducing the pad's size.

A temperature management system is configured to control a temperature of a patient's body using a heat exchange device. The temperature management system is configured to deliver temperature management treatment or therapy to a patient. A user interface of the system is configured to display operational data and patient data on the user interface in a configuration that allows a user to determine or review one or more periods of the performed temperature management treatment.

Disclosed herein is a system, apparatus and method directed to reducing patient contact area of a medical pad for exchanging thermal energy between a targeted temperature management (TTM) fluid and a patient. The system, apparatus and method pertain to a medical pad that includes a fluid containing layer for containing the TTM fluid and a patient contact surface. The fluid containing layer is configured for circulating the TTM fluid within the fluid containing layer. The patient contact surface defines a patient contact area to facilitate thermal energy exchange with the patient. The pad can be segmented into a main pad section and one or more foldable sections configured to be folded by a user, thereby reducing the patient contact area. The circulation of the TTM fluid within the fluid containing layer may be constricted by a fold of the one or more foldable sections while folded.

A temperature management system for ease and timing of priming, setup and/or operation by a user. The temperature management system is configured to control a temperature of a patient's body using a heat exchange device. The temperature management system includes a console that is coupled to a heat exchange device, such as a catheter or surface pad. The console includes a hardware interface for receiving or coupling to a fluid loop configured to supply the heat exchange device with heating or cooling working fluid (e.g., saline). The interface provides instructions, indicators, and/or hardware elements to assist a user in configuring and priming the fluid loop for operation.

The present invention provides an elongated active thermo-regulated neonatal transportable incubator (ANTI), having a main longitudinal axis with a proximal end and an opposite distal end comprising adjacent to at least one of the ends a temperature regulating vent (TRV). The TRV is configured to stream air from one end towards the opposite end substantially along the axis, and the ANTI is configured, by means of size and shape, to accommodate the neonate in parallel to the axis. Further the ANTI can be configured by means of size shape and material to at least partially inserted into an MRD having an open bore in its longitudinal axis, further accommodating the neonate parallel to the MRD bore. An incubator with a temperature regulating vent located outside the incubator and its base.

A system for cooling or heating a body part includes at least one bladder, a pump, a heat exchanger, a first fluid line in fluid communication with the heat exchanger and the at least one bladder, a second fluid line in fluid communication with the at least one bladder and the heat exchanger, a main reservoir and a separator. The heat exchanger is in fluid communication with the pump. The first fluid line is located downstream from the heat exchanger and the second fluid line is located downstream from the at least one bladder when the system is operating to cool or heat the body part. The separator is in fluid communication with the main reservoir and the pump and is located below the main reservoir to receive fluid under the influence of gravity from the main reservoir and to deliver fluid to the pump via gravity.

A thermal transfer device for providing thermal treatment to a patient. A patient support portion supporting and contacting the patient includes a first segment of a fluid flow path to receive a fluid from a fluid source. A flexible covering coupled and movable relative to the patient support portion defines a space therebetween that substantially conforms to the patient. The flexible covering includes a second segment of the fluid flow path. The fluid is circulated through an inlet, an outlet, and fluid flow path for supplying heat to or removing heat from the patient support portion and the flexible covering. A fluid circulation system with a controller may selectively adjust heat transfer from temperature zones defining the patient support portion. The thermal transfer device or a mattress cover may provide for controlling the microclimate, or conditions at or near the interface between the patient and the patient support portion.

This disclosure relates to subnormothermic machine perfusion formulations for ex vivo preservation of allografts, and methods of use thereof.