A fluid delivery line (FDL) for use in transporting a targeted temperature management (TTM) fluid between a TTM module and a thermal contact pad is disclosed. The FDL can include a bi-luminal fluid conduit and a bi-luminal proximal FDL connector. The two lumens of the proximal connector can be concentrically arranged. An authentication tag attached to the FDL can provide authentication data to a TTM module. A TTM system can include a connection adapter added to an existing TTM module where the adapter includes the electro-mechanical valves. An adapter controller operates the valves in accordance with obtained authentication data from the tag. Fluid connection systems can include valves that automatically open and close upon connection and disconnection. Fluid conduits and connectors can include concentrically arranged fluid lumens.

A peristaltic pump has an arcuate raceway with a partially concave inner surface extending through an arc of at least one hundred eighty degrees (180°). The arc defines a midpoint, and a rotor faces the inner surface of the raceway and is both rotatable relative to the raceway and translationally movable relative to the raceway between a pump position, wherein the rotor is spaced from the midpoint a first distance, and a tube load position, wherein the rotor is spaced from the midpoint a second distance greater than the first distance. A motor is coupled to the rotor to rotate the rotor plural are rollers arranged on the rotor to contact tubing disposed between the rotor and the raceway when the rotor is in the pump position. The motor is prevented from stopping at a predetermined angular position to facilitate loading and unloading tubing.

A balloon catheter is used in a closed-loop heat exchange system for manipulating the temperature of a patient. The balloon catheter is positioned in the stomach of the patient, and then expanded with a heat exchange fluid delivered through a lumen formed in the shaft of the catheter. The balloon catheter comes into contact with the wall of the stomach, and the stomach substantially conforms around the expanded balloon catheter. The heat exchange fluid is allowed to flow continuously into and out of the balloon catheter. Heat is exchanged between the balloon catheter and the stomach so as to controllably alter the temperature of at least a portion of the patient. Anti-shivering mechanisms and automatic control based on temperature feedback from the patient may be used in connection with the heat exchange system.

The invention relates to a cardiac lead extraction system, comprising: a handle; an elongated body in communication with said handle; a bendable flexible portion in communication with said elongated body, said bendable flexible portion comprising a first lumen sized and shaped to fit over a cardiac lead; said bendable flexible portion being more flexible than said elongated body; an operational distal end in communication with said bendable flexible portion; where said bendable portion is configured to bend to a bending radius of less than 4 cm while keeping said first lumen open; and where said operational distal end comprises at least one lead extraction assistive tool, said operational distal end comprising a second lumen sized and shaped to fit over a cardiac lead, said second lumen being in communication with said first lumen, and said first lumen comprises an inner diameter of from about 1 mm to about 5 mm.

Systems and methods for minimally invasively delivering radiation therapy to a patient, e.g., with bladder cancer, is provided. The radiotherapy system includes one or more catheters that may be introduced to a patient's anatomical structure via a sheath using an intracavitary approach. The proximal end of the one or more catheters may be coupled to an afterloader for selectively delivering the radiation therapy, and the distal portion of the one or more catheters is transitionable between an uncoiled delivery state within the sheath and a coiled deployed state having a spherical configuration within the anatomical structure of the patient, such that the one or more catheters contacts at least a portion of the anatomical structure in the deployed state.

Disclosed is a system which employs a cooling or heating pad which is preferably rechargeable with hot or cold temperatures at an intended area of the body. The pad includes a highly temperature-conductive or temperature-retentive material which can be cooled or heated using a portable source of heat or cold material delivered to the pad by a removable delivery conduit. Valves can be included to regulate flow of the cooling or heating material from the source to the pad. The system can also include a dual-chambered canister for containing two different media for heating, cooling or for alternating heating and cooling the pad.

A heat exchanger, and method of manufacture of a heat exchanger configured to be placed into contact with an object to regulate the temperature of the object. The heat exchanger comprises a layer of material defining a passage through which a heat transfer fluid may flow. The material layer has a first side for contact with the object; and a second side which, in use, will face away from the object. The first side has a relatively high coefficient of thermal conduction. The second side has a relatively low coefficient of thermal conduction compared to the first side.

Systems for treating a subject's tissue can include a thermally conductive cup, a sealing member, and/or a liner assembly. The systems can include an applicator capable of being reconfigured for a particular treatment site. Components of the applicator can be replaced to achieve a desired configuration. The replaceable components can include contoured heads, liners, and/or sensors. The applicator can draw a vacuum to install various components and/or draw tissue into the applicator. The applicator can cool and/or heat the tissue to affect targeted tissue.

A system for warming or cooling a mammal by affecting blood flow to a portion of the body that is warmed or cooled, the system. The system has at least one magnet having a magnetic field. The at least one magnet contacts, directly or indirectly, the body portion, a second body portion, or combinations thereof to increase blood flow, minimize vasoconstriction and/or encourage vasodilation. The system may have a heating or cooling source for delivering a thermal energy to the surface of the body portion while the at least one magnets increase blood flow, minimize vasoconstriction and/or encourage vasodilation, so that the vasodilation in the body or increased blood flow promotes absorption and transfer of the thermal energy from the body portion's surface to the mammal's core body.

The present disclosure includes devices, systems and related methods useable for controlling a patient's body temperature by endovascular heat exchange as well as body surface heat exchange.