An eye drop bottle storage unit for eye drop administration compliance includes a memory, a processor, and one or a plurality of eye drop bottle pods, where each eye drop bottle pod of the one or said plurality of eye drop bottle pods is configured to hold an eye drop bottle, and comprises one or a plurality of sensors. The memory is configured to store data of an eye drop administration regime of a subject. The processor is configured to receive signals from the one or said plurality of sensors of each eye drop bottle pod, and to determine from the received signals whether the subject administered eye drops into eyes of the subject from each eye drop bottle respectively held in each eye drop bottle pod of the one or said plurality of eye drop bottle pods in accordance with the eye drop administration regime data.

Injector devices and methods for using them to deliver medicament into a patient's body, e.g., sub-retinally within an eye, are provided. The injector includes a cartridge including a piston slidably disposed within an interior for delivering medicament within the interior through an outlet, and a driver including a plunger coupled to the piston, a source of pressurized fluid, and an actuator member for opening a flow path at least partially between the source and the plunger to advance the plunger and piston to deliver medicament from the interior. One or more sensors are operatively coupled to the plunger to measure displacement of the plunger, a processor is coupled to the sensor(s) for analyzing sensor signals to measure volume of medicament delivered from the interior, and an output device, e.g., one or more LEDs or speakers, provide outputs related to the volume of medicament delivered.

An ophthalmic composition comprising Indigo Carmine, or Indigo Carmine and Trypan Blue, for identification of intraocular structures and membranes within the eye, and methods of delivering and using the same, for surgical treatments of the eye, including glaucoma and cataract surgery.

A method of treating a subject having glaucoma comprises performing excimer laser trabeculostomy (ELT) on a subject having glaucoma and having previously undergone a failed treatment or a treatment that has been rendered ineffective by progression of the disease. In some examples, the failed treatment is a non-surgical treatment comprising administering medicated eye drops. In some examples, the failed treatment is a laser treatment or surgical treatment, such as a trabeculoplasty, iridotomy, iridectomy, trabeculectomy, trabeculotomy, goniotomy, surgical insertion of a shunt or implant, deep sclerectomy, viscocanalostomy, or a combination thereof.

A flow control device for a compressible bottle may include a reservoir, the reservoir comprising an ophthalmic formulation disposed therein, the ophthalmic formulation comprising an ophthalmic agent and a preservative; a reservoir interface, disposed at a mouth of the reservoir, the reservoir interface comprising one or more apertures, the one or more apertures in the reservoir interface fluidically connecting an interior of the reservoir and an exterior of the reservoir; a nozzle, the nozzle comprising: an outlet and a nozzle cap, the nozzle cap comprising one or more apertures, the one or more apertures in the nozzle cap fluidically connecting the outlet and a reservoir-facing surface of the nozzle; and an axis of rotation, wherein rotation of the nozzle about the axis of rotation relative to the reservoir aligns the one or more apertures in the reservoir interface with the one or more apertures in the nozzle cap.

Disclosed is an accommodating intraocular lens device for treatment of an eye including a stabilization haptic (120) configured to be positioned within a region of an eye and a lens body having a sealed chamber containing a fixed volume of optical fluid. The lens body includes a shape changing membrane (145) configured to outwardly bow in a region surrounding the optical axis of the eye; a shape deformation membrane configured to undergo displacement relative to the first shape changing membrane; and a static element (150). An inner surface of the shape changing membrane, an inner surface of the shape deformation membrane and an inner surface of the static element collectively form the sealed chamber. The lens device also includes a force translation arm (115) having a first end configured to contact an outer surface of the shape deformation membrane of the lens body and a second end configured to engage a ciliary structure of the eye. The force translation arm is configured to move relative to the lens body upon movement of the ciliary structure.

A method of implanting an intraocular optic assembly that has at least a first and second optics interconnected to one another with a plurality of stanchions can include rotating the first optic and the second optic relative to one another and thereby drawing the stanchions at least one of between the first optic and the second optic and around one of the first optic and the second optic. The method can also include folding, after the rotating, the intraocular optic assembly while retaining the stanchions in the at least one of between the first optic and the second optic and around one of the first optic and the second optic. The method can also include inserting, after the folding, the intraocular optic assembly in an eye through an incision in a cornea of the eye.

An apparatus to maintain an environment over an anterior surface of a patient eye can include an enclosure sized and shaped to be seated about the patient eye to form a cavity within the enclosure. The enclosure can be configured to contain a fluid other than ambient air in contact with the patient eye. The apparatus can include a fluid regulator in communication with the enclosure, where the fluid regulator can be configured to regulate the composition of the fluid contained within the enclosure.

A docking station for a hand-held filament extension atomizer device includes a receiver to receive the device, station electronics, a recharging point for the device arranged to connect with a power source of the device, a power connection to an alternating current power source, and a cleaning reservoir of cleaning solution. A method of operating hand-held dispenser to dispense fluid as a mist includes receiving a signal at a motor contained in a casing in response to a user triggering an actuator on the casing, activating the motor to provide fluid to a filament extension atomizer contained in the case from a reservoir contained in the casing, the motor to cause the filament extension atomizer to generate a mist, and using an air source contained in the casing arranged adjacent the filament extension atomizer to provide air flow to direct the mist to a nozzle that is arranged to allow the mist to exit the casing.

A medical device (100) for the instillation of medical products in droplet form is described, said device comprising a hollow cylindrical body (10) and a rod (20) slidably mobile inside the hollow cylindrical body (10) and provided with a head (21) on which a rubber washer (40) is fixed, which washer, during the sliding of the rod (20), is in contact with an inner surface of the hollow cylindrical body (10). The rod (20) is formed as two portions (22, 24) of different diameter and the device (100) further comprises a sealing bush (30) between the hollow cylindrical body (10) and the rod (20), wherein there is provided a stop (32) which prevents the passage of the portion (22) with a larger circular section of the rod (20).