An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, and an actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy incision to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy.

The invention relates to an eye rinsing element comprising two rinsing fluid discharge areas, wherein each discharge area comprises multiple openings for discharging rinsing fluid.

A delivery device includes a base body having an outlet opening and a chamber for receiving a flowable substance to be administered. The base body, having first and second film portions attached to each other by a connection with a plurality of regions, being configured to discharge the substance through the outlet opening by compressing the chamber. The delivery device further includes a pouring adapter tightly connected to the outlet opening. The plurality of regions of the connection include a more resilient region and a less resilient region that are arranged between the chamber and the outlet opening. When the chamber is compressed to discharge the substance through the outlet opening, the less resilient region is configured to come undone and the more resilient region is configured to remain connected so that the substance can be discharged solely through the outlet opening and the pouring adapter by compressing the chamber.

Devices, systems, and associated methods for detecting drops dispensed by a dropper are provided. For example, a drop detection device may include a light source and a light detector configured to be coupled to a drop dispenser such that the light source and light detector are disposed proximal of a distal dispensing tip of the drop dispenser. The light detector may be configured to receive a reflected portion of a beam of light from the light source, which is reflected by a drop dispensed through the dispensing tip of the drop dispenser. In some embodiments, a processing circuit is configured to analyze a signal provided by the light detector to detect the dispensed drop.

The present invention relates to a kit for ophthalmic solutions contained in screw-cap dropper bottles, which comprises a fastening element and an applicator device for solutions, where the fastening element includes a manual gripping section followed by a cup-shaped cavity suitable for housing the screw-cap of the dropper bottle under pressure; such fastening element has the ability to serve as an extension in order to cap or uncap the screw-cap of the dropper bottle with ease, in addition to keeping such cap coupled to the fastening element while the bottle is in use.

An injection system comprising a syringe barrel; a first sealing element and a second sealing element moveably disposed in the syringe barrel; an injection chamber between them; a puncture element extending from the first sealing element to deliver an injection agent from the injection chamber into a biological space, wherein one or more of the syringe barrel, the first or the second sealing element are configured to prevent proximal movement of the first sealing element past a pre-selected location, while allowing the second sealing element to come in contact with the first sealing element, the system is configured such that, when a force is applied on the second sealing element in a distal direction, in response to a first opposing force, the puncture element advances and in response to a second opposing force, the puncture element remains stationary and the injection agent is conveyed through the puncture element.

A fluid dispensing device includes a cartridge comprising a housing and a head coupled to the housing. The housing forms a first chamber configured to accommodate a fluid; and the head includes a nozzle; and an elastomeric wall that is spaced from the nozzle to form a holding chamber. The holding chamber is in fluid communication with the first chamber and configured to accommodate a portion of the fluid; and the nozzle forms one or more openings to eject the portion of the fluid from the holding chamber. The one or more openings form an oblong shape such that a length of the oblong shape is greater than a width of the oblong shape. The one or more openings can include two parallel slots that together form the oblong shape.

An injector (1) for implanting a sensor implant (2) in the human or animal eye, in particular for the suprachoroidal implantation of a pressure sensor for the wireless measurement of the intraocular pressure, is improved in terms of rapid, complication-free, low-trauma and low-wear suprachoroidal implantation in that, to accommodate the sensor implant, the injector (1) has a substantially tubular injection chamber (8), the inner wall surfaces (9, 10) of which have a non-rotationally symmetrical cross section, preferably an oval or rectangular cross section, in that, at a free end, the injection chamber (8) is provided with an injection opening (13), through which, during implantation, the sensor implant (2) can slide out and slide into a sclera incision in the eye, wherein the inner wall surfaces (9, 10) of the injection chamber (8) enclose the likewise non-rotationally symmetrical cross section of the sensor implant (8) and prevent a rotation of the sensor implant (2) about an axis of rotation extending in the direction of the injection (11).

A package (1) for a fluid formulation (2) to be delivered as a spray or a jet of droplets to an eye (4), comprising an enclosed container (5) a storage recess (6) containing a fluid formulation (2); and a delivery recess (7), adjacent to the storage recess (6). The storage recess (6) and the delivery recess (7) are separated by a fluid barrier (8). Package (1) further comprises a matrix of holes (9), for generating the spray and/or jet of droplets, the matrix of holes (9) opening into the delivery recess (7). The storage recess (6) is configured to expel, by application of an impulse thereto, a dose of fluid formulation (2). The matrix of holes (9) is configured to steer the spray and/or jet of droplets to the target area (3) on the eye (4). Also provided is a device (20) for delivery of the fluid formulation, and a method for delivering the fluid formulation (2) as a spray or a jet of droplets to an eye (4) of a user.

A sampling device includes a container having a body defining a chamber and an opening to the chamber. A septum is bonded to the container to cover the opening and hermetically seal the chamber. The septum has an adherent layer with a first thickness and including a material configured to adhere to a rim of the container to provide a hermetic seal with the container. A metallic foil layer having a second thickness is coupled to the adherent layer. An elastomeric layer having a third thickness is coupled to the metallic foil layer to position the metallic foil layer between the adherent layer and the elastomeric layer. The third thickness is greater than the sum of the first thickness and the second thickness.