An applicator for ophthalmic solutions in single-dose containers includes a structure, an oval rim, a container attachment portion, a hollow and flat support base, and additional features. The structure with open spaces is for inserting, removing, and pressing the single-dose container and allowing the label and the contents of the container to be viewed. The oval rim has a concave upper lip and a concave lower lip to facilitate the positioning of the applicator at an angle between 30 and 60° with respect to a horizontal plane. The features of the applicator enable the device to be used easily, ergonomically, comfortably, and ensure a safe use of the single-dose container in applications after the first use.

Various embodiments of the present disclosure provide systems and methods for managing medication usage. The method performed by a server system includes receiving a plurality of user inputs from a medication monitoring application available in a user device associated with a user. The plurality of user inputs includes an initial medication volume present in a medication dispenser associated with the user, a medication regimen, and dosage schedules of the medication. The method includes tracking a medication usage of the user through the medication dispenser based at least on the plurality of user inputs. The method further includes transmitting an alert message to the user and at least one authorized user of the medication monitoring application to whom the user authorized to share information related to the medication usage based at least on detection of a plurality of medication dispensing events.

Provided herein are needle assemblies for intravitreal injection of an implant into an eye of a patient through an unsheathed state and a sheathed state. Such needle assemblies are precise and accurate for proper treatment and prevent further damage to the eye.

Systems and methods are provided for generating and applying biomimicry tear film layers to a cornea surface. An example method includes forming a multiple layered tear film that are optically transparent, ultra-thin, and smoothly conforming to cornea surface. The multiple layered tear film can include a biomimicry adhesive layer, a biomimicry aqueous layer, and a biomimicry lipid layer. An atomizer/nebulizer/micronizer can be used to generate and applying the biomimicry tear film layers.

The present invention relates to an ultrasound contrast agent for use in treating a retina disorder by transiently disrupting the blood-retinal barrier (BRB) of a human, wherein the ultrasound contrast agent is administered just before and/or during the application, to the retina of the human, of an unfocused ultrasound (US) beam. The present invention further relates to a therapeutically active agent for use in treating a retina disorder in a human, wherein the therapeutically active agent is to be delivered in combination with an ultrasound contrast agent, which is administered before and/or during the application, to the retina of the human, of an unfocused ultrasound (US) beam in order to transiently disrupting the blood-retinal barrier (BRB) of the human, to allow the therapeutically active agent to cross the BRB and to target the retina. The present invention also relates to an eye ultrasound delivery device that may be used to treat a retina disorder.

Provided herein are needle assemblies for intravitreal injection of an implant into an eye of a patient through an unsheathed state and a sheathed state. Such needle assemblies are precise and accurate for proper treatment and prevent further damage to the eye.

The present embodiments relate to a method of treating dry eyes. The method includes a plurality of visits to an eye doctor with each even numbered visit focused on a first eye and each odd numbered visit focused on a second eye. The plurality of visits comprises use of intense pulsed light (“IPL”) therapy, low level light therapy, an ocular nebulizer, dehydrated amniotic membranes, biologic eye drops, advanced lubricants, eyelid debridement, meibomian gland imaging and a slit lamp.

Described here are systems and methods for accessing Schlemm's canal and for delivering an ocular device or fluid composition therein. The ocular devices may maintain the patency of Schlemm's canal without substantially interfering with transmural fluid flow across the canal. The fluid composition may be a viscoelastic fluid that is delivered into the canal to facilitate drainage of aqueous humor by disrupting the canal and surrounding trabeculocanalicular tissues. Tools for disrupting these tissues and minimally invasive methods for treating medical conditions associated with elevated intraocular pressure, including glaucoma, are also described.

A vented protective cap for a liquid dispenser, and a venting insert, in particular for such a protective cap. The protective cap has a cap wall which surrounds a cap interior. The cap wall has a venting aperture which is spanned by a flexible sheet-like structure. A boundary region of the sheet-like structure is fixed in an encircling manner to a boundary of the venting aperture. The sheet-like structure consists of at least two layers which bear directly against one another but, at least in a central region of the sheet-like structure, are not connected fixedly to one another.

This invention relates to a device and method for the vacuum-assisted delivery of drugs through an intact surface membrane of an organ.