This invention describes a wound dressing product for active continuous debridement of devitalized tissues in non-healing wounds including diabetic ulcers, pressure ulcers, burn injuries and other etiologies. The present invention pertains to the principle of continuous wound debridement which makes necrotic tissue more susceptible for removal and hence enhances progressive wound healing. The dressing contains an active ingredient, such as collagenase which serves to debride wounds in-situ. In the present invention purified Collagenase (90% pure) was deposited onto several wound dressing materials. A key feature of this invention is that the activity level of the Collagenase used was substantially preserved.

Disclosed embodiments related to a wound dressing for treating circumferential wounds for use in a negative pressure wound therapy (NPWT). The wound dressing can include a cover layer, a plurality of spacer sections, and a wound contact layer. The wound dressing can further include a port for connection to a source of negative pressure and a connector for fluidically connecting each of the plurality of sections with the port.

A dressing configured to be positioned adjacent to a tissue site can include a cover, a tissue interface, a dressing interface, and a sensing conduit. The dressing interface can be configured to be coupled to the cover and can include a housing, a fluid pathway, and a sensing pathway. The fluid pathway can extend internally through the housing between a fluid inlet cavity and a fluid outlet port. The sensing pathway can extend internally through the housing between a sensing inlet port and a sensing outlet port with the sensing pathway being fluidly isolated from the fluid pathway. The sensing conduit can be configured to be coupled between the sensing inlet port and a tissue contact surface of the tissue interface. Also disclosed are systems, apparatuses, and methods suitable for use with various example dressings.

A clip is disclosed comprising a frame slidably positionable around a structure entering the skin of a patient and a layer to elute a fluid to the skin based on the frame being slidably positioned around the structure.

The present disclosure relates to bandages used to protect and disinfect or provide a protective antimicrobial barrier to a surgical site with one or more percutaneous pins or wires extending therefrom. The bandage includes an antimicrobial agent, an absorbent layer, an adhesive layer, and one or more slits designed to receive therethrough a percutaneous pin or wire extending from the surgical site. The bandage enhances and facilitates the ease of protecting a surgical site with one or more percutaneous pins or wires extending therefrom without disturbing the pins or wires and while protecting the surgical site from infection, contamination, and injury during the healing process.

An absorbent core for an absorbent article is provided an absorbent material, the absorbent core comprising one or more first zones comprising a first amount of absorbent material and one or more second zones comprising a second amount of absorbent material, wherein each second zone is at least partly delimited from the other second zones by the one or more first zones characterized in that the first amount of bulk absorbent material is different than the second amount of absorbent material, each amount of absorbent material being determined as weight per unit area.

Polyurethane material for indicating pH at a locus, preferably as indication of presence of microbes, comprising a polyurethane network having immobilised therein one or more hydrophilic copolymers, the or each said copolymer comprising: hydrophilic monomer; and indicating monomer, which provides an indication in response to a change in hydrophilic state of said hydrophilic monomer and/or copolymer; characterised in that the or each copolymer further comprises one or a plurality of ionisable groups or moieties or polymerisable monomers having one or more characteristic pKa values in the range 5 to 10 and which are responsive to pH at the locus in the range pH 5 to pH 10 and in that hydrophilic state of hydrophilic copolymer is dependent on ionisation of said ionisable groups, moieties or monomers; kit and device comprising the material and process for preparation thereof; and use in detecting or sensing microbes or pH.

A wearable wound management system integrating a flexible microfluidic assembly and real-time electrochemical sensing to autonomously sample, transport, and analyze wound exudate. A Janus membrane, formed by selective deposition of perfluoroalkyl-functionalized silica nanoparticles and O.sub.2 plasma etching on a PET film, may collect fluid via its superhydrophobic wound-facing side and deliver it to a curved, wedge-shaped microfluidic channel that enhances capillary flow. Downstream, a graded PDMS micropillar array refreshes a sensing region by unidirectional fluid movement. A drop-on-demand inkjet-printed, CO.sub.2 laser-patterned flexible sensor patch may measure nitric oxide, oxygen, hydrogen peroxide, pH, temperature, and other relevant metrics. An encapsulated wireless electronic module may transmit health data for wireless monitoring. This system, combined with machine-learning analytics, may enable continuous, in situ monitoring and predictive wound classification, supporting proactive and personalized chronic wound care.

The present invention is directed to a hemostatic textile, comprising: a material comprising a combination of glass fibers and one or more secondary fibers selected from the group consisting of silk fibers; ceramic fibers; raw or regenerated bamboo fibers; cotton fibers; rayon fibers; linen fibers; ramie fibers; jute fibers; sisal fibers; flax fibers; soybean fibers; corn fibers; hemp fibers; lyocel fibers; wool; lactide and/or glycolide polymers; lactide/glycolide copolymers; silicate fibers; polyimide fibers; feldspar fibers; zeolite fibers, zeolite-containing fibers, acetate fibers; and combinations thereof; the hemostatic textile capable of activating hemostatic systems in the body when applied to a wound. Additional cofactors such as thrombin and hemostatic agents such as RL platelets, RL blood cells; fibrin, fibrinogen, and combinations thereof may also be incorporated into the textile. The invention is also directed to methods of producing the textile, and methods of using the textile to stop bleeding.