A filter apparatus, a method for the manufacture of the filter apparatus, the use of the filter apparatus in medical, chemical and/or biotechnological applications, and an apparatus for use in the manufacture of the filter apparatus. The filter apparatus has a cylindrical housing and a plurality of hollow fibers. The hollow fibers are combined to form a bundle in the housing and are embedded and held in each case at the end sides in a molding compound. The filtrate space is filled with particles of a chemically or physically active substance.

The disclosure relates to devices and methods for extracorporeal conditioning of blood. Extracorporeal blood oxygenators and blood oxygenator components, such as conditioning modules, are described. An extracorporeal blood oxygenator includes a conditioning module having an external frame, an inlet cover, an outlet cover, and an internal chamber. A fiber assembly is disposed within the internal chamber and a potting material on the fiber assembly creates a circumferential seal that defines a passageway through the fiber assembly having a substantially circular cross-sectional shape. A fluid inlet is in fluid communication with the passageway, has a lumen that extends along an axis that is substantially perpendicular to the fiber assembly, and has an internal curvilinear surface adjacent the fiber assembly. A fluid outlet on the opposite side of the fiber assembly also has a lumen that extends along an axis that is substantially perpendicular to the fiber assembly.

A membrane distillation module comprises a hollow fiber membrane bundle in a housing. A plurality of hydrophobic hollow fiber membranes is secured at each end in membrane boots by chemical bonding of the fiber membrane to a potting compound. The membrane bundle is supported by supporting rods secured to flanges attached to the membrane boots. Fiber packing density is selected to optimize passage of vapor away from the permeate side of the hollow fiber membranes. A center core spanning the length of the membrane bundle serves to conduct feedwater entering the bottom of the module to a bundle top cap where the feedwater is evenly distributed into the hollow fiber membranes. The housing is configured to accommodate expansion of liquid water to the vapor phase during vacuum membrane distillation and to facilitate exit of water vapor from the module via an outlet connected to a vacuum pump.

Disclosed is a membrane humidifier for a fuel cell, comprising multi-channel hollow fiber membranes having a plurality of channels in various sizes, thus allowing humidifying performance to be maintained in the case of a high rate of flow and to be decreased in the case of a low rate of flow, and thereby preventing flooding. The membrane humidifier for a fuel cell, according to the present invention, comprises: a middle case in which a plurality of hollow fiber membranes are accommodated; a cap case coupled to the middle case; and a fixing unit in which ends of the plurality of hollow fiber membranes are potted, wherein a plurality of channels are formed in each of the hollow fiber membranes, and the difference between the biggest and smallest inner diameters among the inner diameters of the plurality of channels is 30-600 m.

A degassing module includes: a pipe including an in-pipe flow path having a liquid supply port and a liquid discharge port, the pipe having a plurality of holes that allow the in-pipe flow path to be open; a hollow fiber membrane group formed by winding hollow fiber membrane fabric around an outer circumferential side of the pipe, the hollow fiber membrane fabric having a plurality of hollow fiber membranes serving as wefts, and warps; a housing connected to an outer circumferential surface of the pipe and configured to store the hollow fiber membrane group; a partition unit configured to partition a region in the housing into an internal region including an inner circumferential side space of each of the plurality of hollow fiber membranes, and an external region including an inter-membrane space between the plurality of hollow fiber membranes; an air intake port of the housing.

Disclosed herein is a perfusion filtration module or bioreactor for filtering a fluid, wherein the filtration module or bioreactor has a plurality of hollow fiber filter membranes that are splayed to reduce fouling of the filtration array.

A hollow fiber module (1, 1) is made by inserting a bundle of hollow fibers (3) into a housing (2, 2) that has an end closed by a cap (17). A fluid first component (27) that can assume a solid state is introduced into a space adjacent the cap (17) and forms a spacer into which ends of the hollow fibers (6, 7) project. A fluid curable second component (4) is introduced before the first component (27) via a second inflow (28) and is cured to form a sealing layer (9) that embeds the bundle of hollow fibers (3) and seals it with respect to the adjacent housing wall (29, 29). The cap (17) is removed from the module housing (2, 2) along with the first component (27) and ends of the hollow fibers (6) embedded in the first component (27).

Disclosed is a device for adjusting humidification gas of a membrane humidification device of a fuel cell. In particular, the device is adapted to induce changes in differential pressure and velocity of the wet air for each division module and to improve the humidification efficiency by sequentially mounting the division modules divided into various numbers to the interior of a housing of the membrane humidification device, thereby adjusting the density of the hollow fiber membrane filled in each division module.

A cartridge is provided for dialysis or other blood processing therapy. In the cartridge, fibers may be substantially uniformly distributed near a midplane, but near an end, in the inter fiber space, there may be void flow channels, which may cause fluid flow in the inter fiber space to transition within a short region to uniform flow with minimal stagnation zones. Void flow channels may be be radially oriented, introducing fluid from the outer circumference, or axially oriented, introducing fluid along the axial direction through passageways through the potting material. The fluid flow in the inter fiber space may be perpendicular to the fibers, or radial with respect to a cartridge longitudinal axis. The cartridge may have blood flow in the inter fiber space, and flow of dialysate or ultrafiltrate in the lumens of the fibers, or the opposite situation.

Disclosed is a hollow fiber membrane module. The hollow fiber membrane module includes a housing including a first fluid inlet, a first fluid outlet, a second fluid inlet and a second fluid outlet, and hollow fiber membrane bundles, each hollow fiber membrane bundle including a plurality of hollow fiber membranes, disposed within the housing so that a first fluid flows inside the hollow fiber membranes and a second fluid flows outside the hollow fiber membranes, and each hollow fiber membrane bundle further includes porous tubes having both ends closed and including a plurality of pores formed on the side surfaces thereof. The hollow fiber membrane module removes a region, into which a fluid flowing outside a hollow fiber membrane bundle has difficulty in permeating, thus allowing the fluid to uniformly flow. Therefore, even if hollow flow membranes are highly integrated, performance of the hollow fiber membrane module may be maximized.