Described herein are fluid treatment devices for use in tangential flow filtration, comprising a housing unit and a composite material, wherein the composite material comprises: a support member comprising a plurality of pores extending through the support member; and a non-self-supporting macroporous cross-linked gel comprising macropores having an average size of 10 nm to 3000 nm, said macroporous gel being located in the pores of the support member. The invention also relates to a method of separating a substance from a fluid, comprising the step of placing the fluid in contact with an inventive device, thereby adsorbing or absorbing the substance to the composite material contained therein.

Disclosed herein are apparatus and methods for filtering a fluid including a filter module assembly coupled to a manifold. The manifold may include a manifold inlet in fluid communication with a source of feed liquid, an outlet in fluid communication with header of the filter module assembly, a fluid passageway in fluid communication with the manifold inlet, a source of gas, and the outlet, a second fluid passageway in fluid communication with the header and the first fluid passageway and a second manifold outlet vertically displaced from the first manifold outlet and in fluid communication between the first fluid passageway and the second fluid passageway.

The invention relates to a blood treatment device configured to dephosphorylate extracellular adenosine triphosphate (ATP), adenosine diphosphate (ADP), adenosine monophosphate (AMP) and/or lipopolysaccharide (LPS) in the blood of a patient in need thereof in an extracorporeal blood circuit, wherein the device comprises a matrix having alkaline phosphatase (AP) immobilized thereon. The invention further relates to an extracorporeal blood circuit comprising a blood treatment device of the invention and to the blood treatment device for use as a medicament or to methods of treating an infection, preferably a blood or systemic infection, such as sepsis, and/or for the treatment of sepsis-associated acute kidney injury (AKI).

An inkjet printing apparatus which removes gas dissolved in ink by a degassing module provided on an ink supplying path which supplies ink from an ink tank to an inkjet head, includes a liquid feeding pump and a foreign substance removal filter. The liquid feeding pump feeds ink and is provided on the ink supplying path from the degassing module to the inkjet head. The foreign substance removal filter is provided on the ink supplying path from the degassing module to the liquid feeding pump.

Dialyzer systems can consolidate multiple technologies and functionalities of blood treatment systems in a significantly integrated fashion. For example, this disclosure describes dialyzer systems that include a magnetically driven and magnetically levitating pump rotor integrated into the dialyzer. Such a dialyzer can be used with treatment modules that include a magnetic field-generating pump drive unit. In some embodiments, the dialyzers include pressure sensor chambers with flexible membranes with which corresponding pressure transducers of the treatment modules can interface to detect arterial and/or venous pressures.

Disclosed, herein is a single pass cross flow filtration system comprising: a filtration module, comprising two or more filtration segments fluidly connected in series, each having an upstream side and a downstream side; wherein each filtration segment comprises hollow fiber filter membranes, and wherein, when in use, the desired permeate flux is controlled by a configuration comprising: each filtration segment having a selected length; the hollow fiber filter membranes of each filtration segment, having a selected lumen diameter, wherein the selected inner diameter of each filtration segment may be the same or different, provided that at least one selected lumen diameter differs from another selected lumen diameter, and provided that the two or more filtration segments are arranged such that for a given filtration segment, having a selected lumen diameter, no filtration segment on the upstream side of the given filtration segment has a selected lumen diameter that is larger; and one or more pumps, mounted in the permeate channel.