A filtration cell (10) for a biological sample including an upper chamber for receiving the biological sample to be filtered, a lower chamber in fluid communication with the upper chamber, and a filtration membrane (14) positioned between the upper chamber and the lower chamber is disclosed. A surface of the filtration membrane has a contact angle >90°. The flow of the biological sample through the upper chamber may be tangential to the filtration membrane and a filtrate passing through the filtration membrane may be collected in the lower chamber. Also, a method of filtering a biological sample including passing the biological sample through an upper chamber of a filtration cell as described above and collecting a filtrate in the lower chamber is disclosed.

A biological fluid separation device adapted to receive a biological fluid sample having a first portion and a second portion is disclosed. The device includes a housing having a first chamber having a first chamber inlet for receiving the biological fluid sample therein and a first chamber outlet. The housing has a second chamber having a second chamber inlet and a second chamber outlet, and a separation member separating at least a portion of the first chamber outlet and the second chamber. The separation member is adapted to restrain the first portion of the biological fluid sample within the first chamber and to allow at least a portion of the second portion of the biological fluid sample to pass into the second chamber. An actuator, such as a vacuum source, draws the biological fluid sample into the first chamber and the second portion into the second chamber.

A biological fluid separation device adapted to receive a biological fluid sample having a first portion and a second portion is disclosed. The device includes a housing having a first chamber having a first chamber inlet for receiving the biological fluid sample therein and a first chamber outlet. The housing has a second chamber having a second chamber inlet and a second chamber outlet, and a separation member separating at least a portion of the first chamber outlet and the second chamber. The separation member is adapted to restrain the first portion of the biological fluid sample within the first chamber and to allow at least a portion of the second portion of the biological fluid sample to pass into the second chamber. An actuator, such as a vacuum source, draws the biological fluid sample into the first chamber and the second portion into the second chamber.

Disclosed herein is a gas separation membrane comprising a furan-based polymer, an apparatus comprising the gas separation membrane, and a process for separating a mixture of gases using said gas separation membrane. The process comprises contacting one side of a gas separation membrane comprising a furan-based polymer with a mixture of gases having different gas permeances, whereby at least one gas from the mixture of gases permeates preferentially across the gas separation membrane, thereby separating the at least one gas from the mixture of gases.

A blood filtration device comprising a generally cylindrical housing having an interior wall. An interior member is mounted interior of the housing and comprises an outer surface having a porous membrane disposed thereon. The housing and interior member are relatively rotatable and define an annular gap therebetween. The blood filtration device also comprises an inlet for directing fluid into the annular gap, a first outlet for exiting filtrate passing through the membrane, and a second outlet for directing from the annular gap the remaining retentate. The porous membrane comprises a first layer and a second layer.

A blood filtration device comprising a generally cylindrical housing having an interior wall. An interior member is mounted interior of the housing and comprises an outer surface having a porous membrane disposed thereon. The housing and interior member are relatively rotatable and define an annular gap therebetween. The blood filtration device also comprises an inlet for directing fluid into the annular gap, a first outlet for exiting filtrate passing through the membrane, and a second outlet for directing from the annular gap the remaining retentate. The porous membrane comprises a first layer and a second layer.

The invention relates to a dialysis cell for sample preparation for a chemical analysis method, in particular for ion chromatography. The dialysis cell comprises a donor channel and an acceptor channel extending parallel thereto. The donor channel and the acceptor channel are separated from each other by a selectively permeable dialysis membrane. In particular, an analyte that is dissolved in a donor solution in the donor channel can enter through the dialysis membrane into the acceptor solution in the acceptor channel. The acceptor channel has at least in some sections a volume that is smaller than the volume of the donor channel extending parallel thereto. Acceptor and donor channels are formed from half-cells, between which the dialysis membrane is arranged, wherein the donor channel and the acceptor channel are designed in each case as a recess in a contact surface of one of the half-cells with the dialysis membrane.

The invention relates to a dialysis cell for sample preparation for a chemical analysis method, in particular for ion chromatography. The dialysis cell comprises a donor channel and an acceptor channel extending parallel thereto. The donor channel and the acceptor channel are separated from each other by a selectively permeable dialysis membrane. In particular, an analyte that is dissolved in a donor solution in the donor channel can enter through the dialysis membrane into the acceptor solution in the acceptor channel. The acceptor channel has at least in some sections a volume that is smaller than the volume of the donor channel extending parallel thereto. Acceptor and donor channels are formed from half-cells, between which the dialysis membrane is arranged, wherein the donor channel and the acceptor channel are designed in each case as a recess in a contact surface of one of the half-cells with the dialysis membrane.

A device for isolating DNA from a sample containing cells, including a cartridge having an entrance port and an exit port, a membrane disposed between the entrance port and the exit port, and a plurality of channels between the membrane and the exit port. Additionally, systems and methods for isolating DNA from a sample containing cells and also systems and methods for amplifying and isolating single-stranded DNA from a sample containing DNA.

A particle filtration device according to an embodiment of the present invention as a particle filtration device of a lab-on-disk of a rotation type includes: a filtration film that separates particles by filtering a sample; a main chamber connected to the inlet surface of the filtration film and supplying the sample to the inlet surface of the filtration film; an outlet chamber that is connected to the outlet surface of the filtration film and accommodates the filtration fluid from which particles are separated while passing through the filtration film; and a waste fluid chamber connected to the outlet chamber and storing the filtration fluid, wherein the particle filtration device includes a first flow path that connects between the outlet chamber and the waste fluid chamber, and a second flow path that connects between the outlet chamber and the waste fluid chamber but is positioned farther from the center of the lab-on-disk than the first flow path.