Methods and system for real-time monitoring and control of an ultrafiltration/diafiltration (UF/DF) conditioned pool in a UF/DF recovery tank are disclosed. In various embodiments, a UF/DF pool is received at a recovery tank for conditioning or dilution by a buffer. Inline Raman measurements of the conditioned UF/DF pool may be performed and provided to a trained machine learning model as input. The machine learning model can then predict product quality attributes of the UF/DF conditioned pool, examples of said product quality attributes including protein concentration and osmolality of the conditioned UF/DF pool.

A water treatment system is provided. The system includes a prefiltration unit for filtering the untreated water in fluid communication with a source of untreated water. The prefiltration unit produces a prefiltered water from the untreated water. A pump in fluid communication with the prefiltration unit can selectively increase the flow rate of the prefiltered water in a first line, the first line in fluid communication with a membrane element. The membrane element produces a permeate and a retentate from the prefiltered water, the permeate being imparted with a lower concentration of solutes than the retentate. A tank in fluid communication with the membrane element and the prefiltration unit stores prefiltered water from the prefiltration unit and the permeate from the membrane element. One or more valves regulate the flow of prefiltered water and the permeate, and one or more sensors can measure characteristics of the prefiltered water.

A method for evaluating the performance of a water treatment device having a plurality of main vessels arranged in parallel to each other and having a reverse osmosis membrane for separating water to be treated into concentrated water and permeable water, the method including a specifying step of specifying a main vessel having a highest concentration rate among the plurality of main vessels as a target vessel, and a detecting step of detecting an index of the precipitation ease of scale in the water to be detected having a concentration corresponding to a concentration of concentrated water discharged from the target vessel.

A method for evaluating the performance of a water treatment device having a plurality of main vessels arranged in parallel to each other and having a reverse osmosis membrane for separating water to be treated into concentrated water and permeable water, the method including a specifying step of specifying a main vessel having a highest concentration rate among the plurality of main vessels as a target vessel, and a detecting step of detecting an index of the precipitation ease of scale in the water to be detected having a concentration corresponding to a concentration of concentrated water discharged from the target vessel.

To enable energy-saving operation and stable supply of permeate water while water quality level of the permeate water is satisfied during operation, clarified seawater sw subjected to pretreatment and stored in to-be-treated water tank 12 is supplied to reverse osmosis membrane module 14 via clarified seawater supply passage 16. Permeate water pw obtained by an earlier stage element of the reverse osmosis membrane elements 36 of the reverse osmosis membrane module 14 is sent to a subsequent process from permeate water sending passage 46, and permeate water pw obtained by the reverse osmosis membrane element 36 is circulated into the to-be-treated water tank 12 via permeate water circulation passage 48. The flow rate of the clarified seawater sw supplied to the reverse osmosis membrane module 14 is controlled by variable flow rate high-pressure pump 22 provided in the clarified seawater supply passage 16, and opening degree of flow regulating valve 68 provided in the permeate water circulation passage 48 is controlled, whereby the circulation flow rate of the permeate water is controlled.

A reverse osmosis system and method of operating the same includes a membrane housing comprising a reverse osmosis membrane therein. The membrane housing has a feed fluid input, a brine outlet and a permeate outlet; The system further includes a charge pump, a plurality of valves and a tank having a volume comprising a movable partition dividing the volume into a first volume and a second volume. The plurality of valves selectively couples the charge pump to the first volume or the second volume and the brine outlet to the second volume or the first volume respectively.

A reverse osmosis system and method of operating the same includes a membrane housing comprising a reverse osmosis membrane therein. The membrane housing has a feed fluid input, a brine outlet and a permeate outlet; The system further includes a charge pump, a plurality of valves and a tank having a volume comprising a movable partition dividing the volume into a first volume and a second volume. The plurality of valves selectively couples the charge pump to the first volume or the second volume and the brine outlet to the second volume or the first volume respectively.

Embodiments of the disclosure provide a method for evaluating dialyzers used in different medical applications (e.g., hemodialysis). Red blood cell volume lost in a dialyzer is monitored by obtaining blood flowrate measurements and hematocrit measurements at input ports and output ports of the dialyzer. The flowrate and hematocrit measurements are used to determine an accumulation of red cell blood volume in the dialyzer. The measurements may be obtained in a lab environment with an in-vitro blood source or may be obtained in a clinical setting with an in-vivo blood source from a patient.

Provided herein are systems and methods for controlling a membrane-based separation process. The systems and methods can comprise, by one or more computing devices: receiving a product concentration, which product is produced by a process comprising a membrane separation, which process is operated at a first set of operating conditions; optionally calculating a membrane performance parameter based at least in part on the first set of operating conditions; calculating a second set of operating conditions based at least in part on the membrane performance parameter and a model of the process, such that operation of the process at the second set of operating conditions is expected to produce the product within a desired concentration range; and communicating the second set of operating conditions to the process.

Water treatment systems including electrically-driven and pressure-driven separation apparatus configured to produce a first treated water suitable for use as irrigation water and a second treated water suitable for use as potable water from brackish or saline water and methods of operation of same.