This disclosure provides, among other things, a filtration device comprising an open bottomed multi-well plate, a planar spacer that comprises apertures, and a porous capillary membrane. In the device, the planar spacer is sandwiched between the multi-well plate and the porous capillary membrane and the planar spacer is bonded to both the multi-well plate and the porous capillary membrane via an adhesive. Kits and methods of making the device are also provide.

The invention relates to a method for producing a device for material exchange between two mediums, in which at least one mat of semipermeable hollow fibres (3) is wound onto a winding core (2), which has at least one core opening (2a) in its outer surface for a first in- or out-flowing medium, and the winding core (2) is arranged in an axially extending housing (1) having at least one housing opening (1a) for the first in- or out-flowing medium and the axial end regions of the housing (1) are sealed by an adhesive (4) arranged around the hollow fibres (3), wherein at least one chamber region (5) surrounding the hollow fibres (3) is formed via the adhesion between the axial end regions (1b, 1c) of the housing (1) and between the winding core (2) and the housing (1), through which chamber region the first medium can flow via the core opening (2a) and the housing opening (1a), wherein the axial distance between the core opening (2a) and the housing opening (1a) is adjusted to a desired value of multiple possible values via the axial shifting of the winding core (2) relative to the hollow fibre winding (3) arranged around the winding core (2) and relative to the housing (1), and the hollow fibres (3) are adhered to the side of the housing (1) near to the housing opening (1a) in a region between the axial end surface of the housing and the housing opening (1a), and the hollow fibres (3) are adhered to the side of the housing (1) near to the core opening (2a) in a region between the axial end surface of the housing and the core opening (2a). The invention also relates to a number of multiple devices for material exchange between two mediums, wherein all devices comprise at least identical housings (1) and winding cores (2) that are identical at least in regions.

Disclosed is a high-penetration two-component polyurethane adhesive for separation apparatus, such as thin film composite reverse osmosis filtration membranes. The polyisocyanate reactive side of the two-component adhesive comprises hydrogenated castor oil or derivative thereof to increase the viscosity and provide a thixotropic property. Surprisingly, these high-viscosity polyisocyanate reactive components provide a two-component polyurethane adhesive exhibiting excellent penetration of the membranes used in such separation apparatus. Also disclosed is a method of using these two component polyurethane adhesives to bond these membranes to one or more other components of a separation apparatus.

The invention concerns a filtration assembly (1) for microbiological testing and a method of using the filtration assembly for that purpose. The filtration assembly (1) comprises a ring-like membrane support (10) holding a filtration membrane (11), a cylindrical reservoir (20) of which opposite axial ends have openings and one axial opening is removably and fluid-tightly attachable to the membrane support (10) to define a sample volume adjacent to the filtration membrane (11) on one axial side of the membrane support (10); and a drain member (30) removably and fluid tightly attachable to the membrane support (10) to define a drain channel space adjacent to the filtration membrane (11) on an opposite axial side of the membrane support (10).

A hollow fiber membrane module (100) of the present disclosure includes: a plurality of hollow fiber membranes (10); a binding portion (20) binding the plurality of hollow fiber membranes (10) at one end portions thereof; and a cap (30) having an internal space (30s) that communicates with each of the plurality of hollow fiber membranes (10), the cap (30) being integrated with the binding portion (20). Specifically, no other component is present between the binding portion (20) and the cap (30).

A bendable flexible flat membrane module includes: a membrane facing each other and constituting both outer surfaces; a support member made of a flexible material and embedded inside the membrane constituting the both outer surfaces; and a plurality of point bonding portions formed by pressing and bonding the both outer surfaces facing each other at a predetermined point.

Filtration apparatus for the assay of biological and biochemical reactants, for example, is provided and includes a substrate such as a plate having one or more wells open at each end, and a porous membrane positioned in each well forming a discrete filtering area. The filtration apparatus includes a seal that is in a compressible relationship with the face of the porous membrane, the surface of the compression element, and the well wall. Each well includes a compression element, such as an internal well insert or sleeve, which compresses the seal so that the seal contacts the membrane face, the surface of the compression element, and the well wall in a liquid-tight manner. The compression element may be configured so that it is fixed in the well such as by an interference fit with the well wall or by bonding to a surface of the substrate.

The present invention provides a membrane filtration module comprising a housing in which the filtration membrane is disposed in a fixed positional relationship by a potting or bonding material obtained by the curing of a two component (2K) composition consisting of: a first component (A) comprising at least one compound (a) having at least two acetoacetate functional groups; and, a second component (B) comprising at least one compound (b) having at least one amino group, each said amino group being a primary or secondary amino group.

A method of forming a frame around a membrane stack for a laterally-fed membrane chromatography device is provided. The method includes placing a membrane stack having one or more membrane layers on a bottom surface of body of a master mold, the body having opposed side walls and opposed end walls, the opposed side walls spaced apart by a distance greater than a length of the membrane stack, the opposed end walls spaced apart by a distance greater than a width of the membrane stack; placing a cap on the body of the master mold to enclose the membrane stack in the master mold, the cap having at least one opening for injecting a material into a space defined by the end walls of the master mold, the side walls of the master mold, end walls of the membrane stack side walls of the membrane stack, the bottom surface of the body and an inner surface of the cap; injecting the material into the space around the membrane stack; and curing the material to form a frame around the membrane stack.

A membrane assembly for the permeative separation of a fluid from fluid mixtures includes a porous, fluid-permeable, metallic support substrate, a membrane that is disposed on the support substrate and is selectively permeable to the fluid to be separated off, and a connecting part which is formed, at least on the surface, of a fluid-tight, metallic material. The support substrate is cohesively bonded along a peripheral section thereof to the connecting part. A ceramic, fluid-permeable, porous, first intermediate layer is disposed between the support substrate and the membrane. At least one ceramic bonding layer is disposed directly on the connecting part and the material bond and extends at least over the cohesive material bond and an adjoining section of the connecting part. The first intermediate layer ends on the bonding layer and has a greater average pore size than the bonding layer.