A membrane capsule for biological and chemical separations comprising a cassette comprising an upper surface and a lower surface adjoined by a cassette sidewall, an inlet and an outlet located on the upper and lower surfaces of the cassette, tubes fluidly connected to the inlet and the outlet, holes or slots in the tubes to facilitate separation, and a membrane wrapped, pleated, and/or spiral wound around each of the tubes. Methods of separation comprising flowing fluid flow through the inlet of the membrane capsule, allowing the fluid to permeate through the holes or slots of the tubes, separating biological and/or non-biological substances, collecting the fluid within a reservoir, and draining fluid from the reservoir.

A gas exchange system, said system comprising: a plurality of cartridges, each having a casing, said casing having a cartridge inlet adjacent to a first end and a cartridge outlet adjacent to an opposed second end; each casing having a bore in which is placed a gas permeable, liquid impermeable, hollow membrane; each hollow membrane having a membrane inlet arranged to receive a gas from an inlet chamber and a membrane outlet for venting said gas; each cartridge inlet in communication with a concentration zone, and arranged to receive a solvent from said concentration zone, so as to exit said solvent through said cartridge outlet; wherein said bore is arranged to flow said solvent adjacent to said hollow membrane so as to permit the exchange of gas through said gas permeable, liquid impermeable membrane.

A gas trap assembly including a base connector housing including an inflow port and an outflow port, a reservoir fluidly connecting the inflow port to the outflow port, and a grooved porous media located within the reservoir. The grooved porous media including a plurality of grooves and composed of a material having a plurality of pores of a selected size. The grooved porous media fluidly divides the reservoir into two portions in such a way that a working fluid flowing from the inflow port to the outflow port must flow through the plurality of grooves and the plurality of pores of the grooved porous media. The plurality of grooves and the plurality of pores are configured to prevent gas from passing through the grooved porous media.

The present disclosure provides a cell separation apparatus for a bioreactor. The cell separation apparatus may be disposed outside the bioreactor and in fluid connection with the bioreactor, the cell separation apparatus may be in a shape of a box body, the cell separation apparatus may include a liquid buffer device including a first liquid cavity disposed in the box body; a filter device including a filter channel and a filter membrane disposed in the box body, the filter membrane may be disposed above the filter channel; and a first liquid channel may be configured in the box body to facilitate a fluid communication between the first liquid cavity and the filter channel. A power system for filtering and microfluidic channels are integrated in the cell separation apparatus that is of a box shape, thereby reducing the volume and production cost thereof.

Methods of filtering a liquid feed are disclosed. In one version, the method comprises passing a liquid feed through a single pass tangential flow filtration (SPTFF) system and recovering the retentate and permeate from the system in separate containers without recirculation through the SPTFF system. In another version, the method of filtering a liquid feed, comprises passing a liquid feed through a tangential flow filtration (TFF) system, recovering permeate and a portion of the retentate from the system in separate containers without recirculation through the TFF system, and recirculating the remainder of the retentate through the TFF system at least once. The methods can be performed using an SPTFF or a TFF system that comprises manifold segments to serialize the flow path of the feed and retentate without requiring diverter plates.

Described are liquid filter apparatuses that include a housing, an interior within the housing, a cartridge assembly (otherwise known as a “filter cartridge”) contained within the housing, and a vent that allows gaseous fluid from an interior of the housing to be released to an exterior of the housing, or that include an electrostatic charge mitigation feature, as well as related methods.

A desalination system, including a membrane distillation portion, a solar power concentration portion, and a thermal vapor compression portion operationally connected to the membrane distillation portion and to the solar power concentration portion. The membrane distillation portion includes a first vessel having a first portion and a second portion separated by a hydrophobic membrane operationally connected therebetween and oriented to pass water from the first portion to the second portion, wherein the hydrophobic membrane further comprises a hydrophilic membrane and an air blocking layer connected to the hydrophilic membrane and disposed in the first portion, a vacuum gap adjacent the hydrophobic membrane and disposed in the second portion, a first fluid inlet and a first fluid outlet operationally connected to the first portion, and a second fluid inlet and a second fluid outlet operationally connected to the second portion. The solar power concentration portion includes a pump having a pump outlet and a pump inlet operationally connected to a water line and to the vacuum gap, a linear Fresnel mirror collector for collecting and focusing sunlight, and an outlet line operationally connected to the pump outlet and positioned to receive focused sunlight from linear Fresnel mirror collector. The thermal vapor compression portion includes an ejector having an ejector inlet portion and an ejector outlet portion, wherein the ejector inlet portion is operationally connected to the outlet line and to the vacuum gap, a second vessel fluidically connected to the outlet portion and further including a heat exchanger operationally connected to the ejector outlet portion and to a water pipe, a feed spray operationally connected to the second outlet and positioned to spray into the heat exchanger, and a collection portion for receiving concentrated feed spray. The heat exchanger receives desalinated water from the ejector and from the feed spray. The water line carries desalinated water from the heat exchanger. The first outlet passes concentrated brine, and the first inlet receives feed water to be desalinated.

A hollow fiber membrane module includes one pressure vessel, and at least one hollow fiber membrane element loaded in the pressure vessel. Each of the element includes a plurality of hollow fiber membranes each having openings at both ends, a bypass tube, and a supply port and a discharge port provided on one end side in a longitudinal direction. The supply port is in communication with inflow-side openings of hollow fiber membranes. The bypass tube is provided in the longitudinal direction of the element, has an inflow port at an end portion on a side of outflow-side openings of the hollow fiber membranes, and has an outflow port at an end portion on a side of the inflow-side openings of the hollow fiber membranes. The outflow-side openings of hollow fiber membranes are in communication with the inflow port, and the outflow port is in communication with the discharge port.

Silicon carbide flat sheet filtration membranes are supported on one piece manifold/end cap structures. Ends of a large number of the parallel flat plate membranes are fitted into elongated end cap slots that are part of a single molded manifold/end cap structure, such a structure being at each end of the series of membranes. In addition, a one piece external frame module can be provided to receive the gang of flat plate membranes with attached manifold/end caps. In the event of a damaged plate, the plate can be removed and replaced along with a special end cap repair section. This provides advantages over prior arrangements with individual end caps for each module or potting of the flat plates into a box or chamber.

A module comprises a cell stack having a plurality of alternating ion depleting compartments and ion concentrating compartments, an inlet manifold configured to facilitate a flow of fluid into the cell stack, and a first flow distribution system, associated with the inlet manifold, including a first ramp to promote the circulation of the flow of fluid into the cell stack.