A portable water conditioning system is provided that includes an incoming water inlet; a reverse osmosis stage in fluid communication with the incoming water inlet, the reverse osmosis stage having a permeate outlet and a concentrate outlet; a diversion device having a diversion valve, the diversion valve placing the concentrate outlet in fluid communication with a waste water outlet; a deionizing stage in fluid communication with a pure water outlet; a bypass valve configured to selectively place the permeate outlet in fluid communication with one or more of the waste water outlet, the deionizing stage, and the pure water outlet; and a controller configured to control the diversion device and the bypass valve to provide water at the pure water outlet of a desired condition.

A portable water conditioning system is provided that includes a water conditioner, a first sensor, a second sensor, and a controller. The water conditioner has a plurality of conditioning stages that condition water. The plurality of conditioning stages include, in a direction of flow of the water through the water conditioner, a reverse osmosis stage and a deionizing stage. The first sensor detects a first condition of the water before the reverse osmosis stage. The second sensor detects a second condition of the water after the reverse osmosis stage. The controller is in communication with the first and second sensors and determines a health status of the reverse osmosis stage based the first and second conditions. The first and second conditions each include a level of total dissolved solids of the water.

Systems and methods provide automated parameter assurance features and results for consumables used in bioprocessing and particularly for purifying, filtering, harvesting and collecting bioprocessing fluids. Consumables having these features are sized, shaped, configured and constructed to interface with and be a component of such a bioprocessing system that includes a multi-use component or device with which it operatively engages such as by docking, engagement with a connector or other approach that allows for insertion and removal of the consumable. The consumable may be a component having a single-use life or a limited life. Each consumable has a median by which information, which can include use limits and specifications, is associated with that specific consumable, and those limits and specifications are communicated to the multi-use component which indicates any inappropriateness for use with the multi-use component.

Parallel membrane elements are arranged in parallel within a pressure vessel. A sealing body is disposed within the pressure vessel and is compressed against an inner surface of the pressure vessel to provide a leak-right seal in between a feed gas side of the sealing body and a non-permeate side of the sealing body. The sealing body may be slid within the pressure vessel without damaging the sealing body and in all cases without requiring mechanical assistance.

A container for liquids is provided, in which pressurization of the container is used to force the liquid through one or more membranes to an output. The membranes are disposed across substantially an entire length of the container, and pass liquid in preference to the air. As a result, the liquid may be extracted from the container in any orientation. A particular use for this kind of container is as a portable water bottle containing a filter.

Disclosed herein are apparatus and methods for filtering a fluid including a filter module assembly coupled to a manifold. The manifold may include a manifold inlet in fluid communication with a source of feed liquid, an outlet in fluid communication with header of the filter module assembly, a fluid passageway in fluid communication with the manifold inlet, a source of gas, and the outlet, a second fluid passageway in fluid communication with the header and the first fluid passageway and a second manifold outlet vertically displaced from the first manifold outlet and in fluid communication between the first fluid passageway and the second fluid passageway.

A method of operating an immersed microporous membrane module includes a step of monitoring membrane performance to sense the onset of sludging in the module. Differences in permeability between permeation in backwashes, or trends in permeability during backwashing and permeability during permeation, or both, are monitored. Solid deposits formed during the onset of sludging may be removed with an in situ de-sludging process. For example, the deposits may be removed by stopping permeation while aerating the module, optionally at an increased rate. At other times, the module is optionally aerated while permeate is withdrawn at an aeration rate correlated to flux. The method may be used in particular with a membrane module having parallel textured flat sheet membranes suspended between a pair of vertically oriented headers. An aerator may be made from an open bottomed channel having an array of holes rising and concentrated towards the center of the channel.

The invention concerns a filtration device comprising a providing fluid connection and mechanical connection comprising a clamping plate movably mounted relative to the manifold and adapted to compress at least one cassette against the manifold, means for driving and guiding the clamping plate comprising a rod extending between the manifold and the plate, an actuator provided with a body and a member moveable relative to the body, which member is adapted to move through a predetermined travel between an extended position and a retracted position, the body being carried by the manifold, and the member carrying the rod and driving the plate via the rod to a clamped position in which the member is in an intermediate retracted position in which it has moved through a shorter travel than the predetermined travel relative to its extended position.

A tangential flow filtration manifold takes a modular form for interconnection in a manifolded arrangement for aggregating a total filtration area of the aggregate filter (membrane) surface. A plurality of modular TFF cassette filters may be or stacked on the TFF manifold such that it allows the number of interconnected filters, as well as the membrane surface area within each cassette, to be readily reconfigured. A single output, or filtrate connection on the TFF manifold simplifies fluidic plumbing connections for directing and gathering the filtrate (permeate) produced as output.

A modular header for a filtration module assembly is provided. The modular header includes a main body, a first liquid passageway and a second liquid passageway extending through the main body, and a gas passageway extending through the main body. The gas passageway has a first open end formed at a first side surface of the main body and an opposing second open end formed at a second side surface of the main body. An auxiliary adapter is secured to the main body at at least one of the first and second open ends of the gas passageway.