The reverse osmosis system with at least one high pressure pump, which supplies untreated water to at least one module pipe, in which a membrane with a permeate collecting pipe is arranged, includes a permeate outlet of the at least one module pipe that is connected by means of a first conduit to a permeate tank, which is in communication by means of a further conduit, connected into which there is a permeate supply pump, with a loop feed line, to which a plurality of dialysis devices are connected and that branching off from the first conduit there is a bypass conduit, which discharges into the further conduit downstream of the permeate tank and the permeate supply pump.

Provided is a water purifier comprising: a filter unit filtering water supplied from a water source, including a reverse osmosis filter; a discharge unit discharging water filtered by the filter unit externally; a flushing portion connected to the reverse osmosis filter; and a controller configured to flow water filtered by the reverse osmosis filter to the flushing portion, and to flush the reverse osmosis filter.

A fluid filtration assembly includes a filter housing having a first end for fluid connection with a fluid storage vessel. A filter cartridge is disposable within the filter housing, and a plunger pump is coupled at a second end of the filter housing. The plunger pump includes a housing having a rigid portion and a flexible portion. The flexible portion has a plunger-engaging portion for coupling to the plunger of an actuator. The flexible portion selectively movable with respect to the rigid portion via the actuator. The filter cartridge can be a hollow fiber filter. The plunger pump can be configured to induce alternating tangential flow in at least a portion of the assembly. The fluid filtration assembly can be provided as a disposable single-use arrangement.

A blood treatment system and method controlling same are provided. The system comprises a blood pump for urging blood from an arterial or venous interface through a blood flow path; a dialyser in fluid communication with said blood flow path for ultrafiltering the blood to remove fluid therefrom; a fluid removal pump in fluid communication with said dialyser for urging ultrafiltered fluid away from said dialyser; a controller in signal communication with said blood pump; and a reversing valve for selectively reversing direction of blood flow in at least a portion of the blood flow path under signal control of said controller. The blood pump is selectively activatable under signal control of the controller.

A submersible reverse osmosis desalination apparatus uses low temperature concentrate or brine from the desalination apparatus to provide a high volume cold liquid stream to an Ocean Thermal Energy Conversion (OTEC) heat engine. The OTEC engine also employs a warm liquid stream and uses the cold and warm liquid streams to obtain electrical power from a closed-cycle or open-cycle heat exchange and generator system. Use of the concentrate or brine stream provides a much greater liquid volume and much greater cold thermal energy content than would be obtained by using cold desalinated product water from the desalination apparatus in the OTEC heat engine.

A device for tangential flow filtration of a fluid includes a filter unit having has a first fluid opening and a second fluid opening for the fluid, a filter element and a permeate opening to discharge a permeate filtered out of the fluid, a first flow connection to connect the first fluid opening to a reservoir for the fluid, a second flow connection to connect the second fluid opening to the reservoir for the fluid, a first pump in the first flow connection, and configured to convey the fluid from the reservoir to the filter unit :a third flow connection configured to enable a fluid communication between the first flow connection and the second flow connection, the third flow connection bypassing the filter unit, and a second pump configured to circulate the fluid through the third flow connection and the filter unit.

A portable filtration system is described. The system may comprise: a mixing portion, comprising: a pump adaptor and a contaminant regulator. The pump adaptor may comprise: an upper plate, a lower plate, and a screen. The screen may axially extend between the upper and lower plates, wherein the upper plate, the lower plate, and the screen define a channel of a mixing chamber. The contaminant regulator may comprise a through-passage coupled to the upper plate, wherein the through-passage is in fluid communication with the mixing chamber.

The disclosure provides a filtration system for a cell culture apparatus and a method of cell culture. The filtration system comprises a bioreactor vessel and two or more alternating tangential flow (ATF) filters connected in parallel. A failure in either filter is detected by an in-line sensor, and an automated response system functions to sequester the malfunctioning filter by stopping the flow of liquid media through the filter. Media flow through the remaining operable filters can be increased so that the rate of perfusion through the bioreactor remains relatively unchanged. Such a system may prevent issues that arise from ATF filter failures in conventional perfusion bioreactors, thereby improving the long-term viability of cell cultures.

A contactor system includes a plurality of contactor panels. Each contactor panel includes a frame member and a membrane array adapted to be received within the frame member. The membrane array defines a first end portion, a second end portion, and a plurality of hollow fibers. The contactor system also includes a first manifold in selective fluid communication with the first end portion of the membrane array of each contactor panel. The contactor system further includes a second manifold in direct fluid communication with the second end portion of the membrane array of each contactor panel. The contactor system includes a controller configured to provide selective fluid communication between the first manifold and the first end portion of the membrane array of each contactor panel.

A system and method for moving water up a water column to achieve a sufficient pressure to overcome a reverse osmosis filter. The system includes a rigid outer column for receiving and holding water, with an inner, deformable hose located inside the rigid outer column. The hose has a one-way valve at a distal end of the hose to allow water to enter the hose and an outlet at the proximal end of the hose to allow water to exit the hose. A water-raising device to raise the water within the inner, deformable can include a system that moves sections of water within an inner lumen using a peristaltic motion to drive water upwardly through the inner lumen.