Examples disclosed herein relate to a dispensing device including a syrup unit which transmits via one or more orifices one or more syrups and water to a dispensing block, a syrup source coupled to the syrup unit which provides the one or more syrups to the syrup unit, a water source which provides water to the syrup unit, and a cf valve coupled to a first orifice upstream of a solenoid valve where the cf valve provides a first range of pressures to the solenoid valve and where the first orifice is coupled to the dispensing block.

A beverage container has a housing, a controllable flow restriction element, and at least two liquid storage compartments in the housing. The housing is relatively rotatable with respect to the controllable flow restriction element about a main axis for rotation of the controllable flow restriction element between a closed liquid flow position and an open liquid flow position. The controllable flow restriction element has openings therein within the housing. Rotation of the controllable flow restriction element toward the closed position effects the closed position. Mixing of liquids from the first liquid compartment and the second liquid compartment are effected by rotational movement of the controllable flow restriction element.

A beverage container has a housing, a controllable flow restriction element, and at least two liquid storage compartments in the housing. The housing is relatively rotatable with respect to the controllable flow restriction element about a main axis for rotation of the controllable flow restriction element between a closed liquid flow position and an open liquid flow position. The controllable flow restriction element has openings therein within the housing. Rotation of the controllable flow restriction element toward the closed position effects the closed position. Mixing of liquids from the first liquid compartment and the second liquid compartment are effected by rotational movement of the controllable flow restriction element.

An inline buffer dilution system is provided that includes a first flow control valve fluidly connected to a supply of diluent liquid, second and third flow control valves fluidly connected to supplies of a first buffer and a second buffer, respectively, and a mixing pump fluidly connected to the first, second, and third flow control valves and configured to mix an amount of the diluent liquid, the first buffer, and the second buffer to produce a diluted buffer solution. The system further includes a backpressure control valve configured to generate a backpressure that promotes mixing within the mixing pump, and a controller configured to control the backpressure based on the amount of the diluent liquid, the first buffer, and the second buffer being mixed in the mixing pump, such that the mixing pump yields a minimum mixing threshold across a range of fluid flows.

An inline buffer dilution system is provided that includes a first flow control valve fluidly connected to a supply of diluent liquid, second and third flow control valves fluidly connected to supplies of a first buffer and a second buffer, respectively, and a mixing pump fluidly connected to the first, second, and third flow control valves and configured to mix an amount of the diluent liquid, the first buffer, and the second buffer to produce a diluted buffer solution. The system further includes a backpressure control valve configured to generate a backpressure that promotes mixing within the mixing pump, and a controller configured to control the backpressure based on the amount of the diluent liquid, the first buffer, and the second buffer being mixed in the mixing pump, such that the mixing pump yields a minimum mixing threshold across a range of fluid flows.

An adapter for connecting one or more storage containers with a syringe is described. The adapter includes a first port that provide a connection with a first container volume, a second port that provides a connection with a second container volume, a third port that provides a connection to a syringe. The adapter further includes a mixing channel extending from a first end in fluid communication with the third port to a second end. The mixing channel includes a tortuous path along at least a portion of its length. The mixing channel enables two constituents of a pharmaceutical complex to be mixed through the mixing channel to form the pharmaceutical complex. Also disclosed is a system including such an adapter, a method of mixing two constituents of a pharmaceutical complex via such an adapter and a method of manufacturing such an adapter.

An adapter for connecting one or more storage containers with a syringe is described. The adapter includes a first port that provide a connection with a first container volume, a second port that provides a connection with a second container volume, a third port that provides a connection to a syringe. The adapter further includes a mixing channel extending from a first end in fluid communication with the third port to a second end. The mixing channel includes a tortuous path along at least a portion of its length. The mixing channel enables two constituents of a pharmaceutical complex to be mixed through the mixing channel to form the pharmaceutical complex. Also disclosed is a system including such an adapter, a method of mixing two constituents of a pharmaceutical complex via such an adapter and a method of manufacturing such an adapter.

There is disclosed a capillary microfluidic circuit including a main channel communicating with a flow inducing element. The main channel has intermediary inlets. Reservoirs for containing one or more liquids prior to being drawn into the main channel. The reservoirs include a first reservoir and at least a second reservoir. Each of the reservoirs has an upstream end connectable to vents for filling the reservoirs with the one or more liquids and a downstream end. The downstream end of each of the reservoirs is connected to the intermediary inlets of the main channel A conduit is disposed between the first reservoir and the a least a second reservoir. The conduit links the downstream end of the first reservoir with the upstream end of the at least a second reservoir.

There is disclosed a capillary microfluidic circuit including a main channel communicating with a flow inducing element. The main channel has intermediary inlets. Reservoirs for containing one or more liquids prior to being drawn into the main channel. The reservoirs include a first reservoir and at least a second reservoir. Each of the reservoirs has an upstream end connectable to vents for filling the reservoirs with the one or more liquids and a downstream end. The downstream end of each of the reservoirs is connected to the intermediary inlets of the main channel A conduit is disposed between the first reservoir and the a least a second reservoir. The conduit links the downstream end of the first reservoir with the upstream end of the at least a second reservoir.

An exemplary compounding system and method can include a transfer set that includes a manifold for assisting in transferring a plurality of ingredients from supply container(s) to a final container. The manifold can include a first channel in fluid communication with at least one primary ingredient, and a second channel in fluid communication with a plurality of secondary ingredients. The first channel and second channel can be in fluid isolation from each other such that the at least one primary ingredient does not mix with the plurality of secondary ingredients within the manifold. The transfer set can include a plurality of inlet lines in fluid communication with the manifold and two outlet lines configured for connection to two separate pumps and eventually being in fluid communication with the final container.