A lipid nanoparticles manufacturing chip includes a mixer unit for forming a mixed solution by mixing a first raw material containing an active ingredient and a second raw material containing a lipid, a dilution unit that is connected to the mixer unit and dilutes the mixed solution using a diluent solution to make a diluted mixed solution, and a concentration unit connected to the dilution unit and for obtaining a concentrated solution by concentrating lipid nanoparticles (LNP) from the diluted mixed solution.

Embodiments of the present application relate to batches of bupivacaine multivesicular liposomes (MVLs) prepared by a commercial manufacturing process using independently operating dual tangential flow filtration modules.

Embodiments of the present application relate to batches of bupivacaine multivesicular liposomes (MVLs) prepared by a commercial manufacturing process using independently operating dual tangential flow filtration modules.

Shown and described is a device (100) for dosing and/or preparing a mixture of substances, in particular a medium or a buffer, the device (100) comprising: at least one first container (102), which is designed to receive at least one solid component, at least one first dosing device (104) for dosing the at least one solid component, the first dosing device (104) being connected to or can be connected to the first container (102), at least one fluid connection (110, 110′) to connect to at least one second container (103, 103′), which is designed to receive at least one fluid, and/or a fluid line for supplying a fluid, and at least one second dosing device (108, 108′) for dosing the at least one fluid, the second dosing device (108, 108′) being connected or connectable to the second container (103, 103′) or to the fluid line, respectively. the fluid line, wherein the at least one second container (103, 103′) and/or the at least one second dosing device (108, 108′) are replaceable and are developed as disposable articles, and/or wherein the at least one first container (102) and/or the at least one first dosing device (104) are replaceable and are developed as disposable articles.

Embodiments of the present application relate to batches of bupivacaine multivesicular liposomes (MVLs) prepared by a commercial manufacturing process using independently operating dual tangential flow filtration modules.

Embodiments of the present application relate to batches of bupivacaine multivesicular liposomes (MVLs) prepared by a commercial manufacturing process using independently operating dual tangential flow filtration modules.

Embodiments of the present application relate to commercial manufacturing processes for making bupivacaine multivesicular liposomes (MVLs) using independently operating dual tangential flow filtration modules.

Embodiments of the present application relate to commercial manufacturing processes for making bupivacaine multivesicular liposomes (MVLs) using independently operating dual tangential flow filtration modules.

The present invention relates to a device (60) for manufacturing pharmaceutical compositions, comprising: a support (62); a mixing container (16); a plurality of reservoirs (18, 20) containing starting materials for the composition of a medicament; at least one dispensing device (64, 66) that is designed to dispense an amount of a starting material into the mixing container, wherein the dispensing device is assembled, or is designed to be assembled, with a reservoir; a stirring device (68) that is able to stir the mixing container and/or the contents of the mixing container; and an electronic module (74) for controlling the at least one dispensing device.

Provided is an UFB generating apparatus and an UFB generating method capable of efficiently generating an UFB-containing liquid with high purity. To this end, the ultrafine bubble generating apparatus includes a pre-processing unit that performs predetermined pre-processing on a liquid W and a generating unit that generates ultrafine bubbles in the liquid on which the pre-processing is performed. The generating unit generates the ultrafine bubbles by causing a heating element, which is provided in the liquid on which the pre-processing is performed, to generate heat to generate film boiling on an interface between the liquid and the heating element.