The present invention provides an ultrafine bubble-containing liquid producing apparatus capable of reducing the possibility of intermitting supply of a UFB-containing liquid. An ultrafine bubble-containing liquid producing apparatus includes producing units that produce an ultrafine bubble-containing liquid containing ultrafine bubbles by using a liquid supplied from a liquid introducing unit and deliver the produced ultrafine bubble-containing liquid to a liquid delivering unit. The producing units include a plurality of ultrafine bubble generating units capable of operating independently. Each of the plurality of ultrafine bubble generating units is provided to be capable of independently switching between communicating with and being disconnected from the liquid introducing unit and the liquid delivering unit.

A dispensing device, comprising a plurality of microfluidic pumps, microfluidic valves, and a microfluidic mixer chip, for receiving and mixing microfluidic amounts of a plurality of fluids having differing viscosities, is disclosed. The device includes a plurality of pathways for moving fluids from associated reservoirs to the microfluidic mixer chip. A mix controller controls the microfluidic pumps and valves so that the fluids, having different viscosities, can be accurately mixed at specified microfluidic amounts or volumes according to a specified microfluidic recipe, and the microfluidic mixture dispensed from the device. The device can be in communication with a software application implemented on a mobile compute device, such as a smartphone, and receive instructions for implementing the specified microfluidic recipe from the software application such that the operation of device components is at the direction of the software application executed on the mobile compute device.

A dispensing device, comprising a plurality of microfluidic pumps, microfluidic valves, and a microfluidic mixer chip, for receiving and mixing microfluidic amounts of a plurality of fluids having differing viscosities, is disclosed. The device includes a plurality of pathways for moving fluids from associated reservoirs to the microfluidic mixer chip. A mix controller controls the microfluidic pumps and valves so that the fluids, having different viscosities, can be accurately mixed at specified microfluidic amounts or volumes according to a specified microfluidic recipe, and the microfluidic mixture dispensed from the device. The device can be in communication with a software application implemented on a mobile compute device, such as a smartphone, and receive instructions for implementing the specified microfluidic recipe from the software application such that the operation of device components is at the direction of the software application executed on the mobile compute device.

Provided is an UFB generating apparatus and an UFB generating method capable of efficiently generating an UFB-containing liquid with high purity. The ultrafine bubble generating apparatus includes a generating unit that generates ultrafine bubbles in a liquid and a post-processing unit that performs predetermined post-processing on the ultrafine bubble-containing liquid generated by the generating unit. The generating unit generates the ultrafine bubbles by causing a heating element, which is provided in the liquid on which the pre-processing is performed, to generate heat to generate film boiling on an interface between the liquid and the heating element.

Disclosed is a sample processing method for processing a target component in a sample by use of a sample processing chip having a storage portion and a droplet forming flow path, the sample processing method including: storing, in the storage portion, a mixture of the target component and a predetermined amount of a diluent for causing the target component to be encapsulated by one molecule or by one particle into a droplet; heating the mixture in the storage portion to cause thermal convection in the storage portion thereby to mix the target component and the diluent together; and in the droplet forming flow path, forming droplets in a dispersion medium, each droplet containing the diluted target component and a reagent that reacts with the target component.

The present disclosure provides a system for the internal and external modification of nanoparticles in a continuous process. The system includes (a) a first inlet, (b) a second inlet, (c) a first pump in fluid communication with the first inlet, (d) a second pump in fluid communication with the second inlet, (e) a first flow meter positioned between the first pump and the first mixer, (f) a second flow meter positioned between the second pump and the first mixer, and (g) a mixing chamber in fluid communication with the first flow meter and the second flow meter, and (h) a first heat exchanger in fluid communication with the mixing chamber.

An object of the present disclosure is to improve the generation efficiency of a UFB-contained liquid in a generation apparatus having a circulation mechanism. One embodiment of the present invention is an ultra fine bubble generation apparatus including: a first tank that stores a liquid; a generation unit configured to generate an ultra fine bubble in the liquid output from the first tank; a second tank that stores the liquid output from the generation unit; and a liquid passage that inputs again the liquid stored in the second tank to the first tank, and the ultra fine bubble generation apparatus includes a blocking configuration that blocks an ultra fine bubble included in the stored liquid from being input again to the first tank.

Provided is an ultrafine bubble generating method and an ultrafine bubble generating apparatus capable of efficiently generating a UFB-containing liquid with high purity. To this end, a flow passage inner volume is varied by using a flow passage inner volume varying element, the liquid is pressurized such that the liquid passes through a narrow portion at high speed and flows into a depressurizing area.

The present invention provides a fine bubble generating apparatus capable of generating fine bubbles efficiently. The present invention includes a fluid flow passage that includes a narrow portion in at least a part thereof, a heating part capable of heating a liquid flowing through the fluid flow passage, and a controlling unit that controls the heating part. The controlling unit controls the heating part to generate film boiling in the liquid to generate ultrafine bubbles.

The apparatus includes: a producing unit that generates ultrafine bubbles in a liquid supplied from a liquid introducing unit to produce an ultrafine bubble-containing liquid containing the ultrafine bubbles, and delivers the ultrafine bubble-containing liquid; a liquid delivering unit that delivers the ultrafine bubble-containing liquid to an outside; a buffer tank that receives the liquid delivered from the producing unit and delivers the liquid to the liquid delivering unit; and a controller that controls the delivery of the ultrafine bubble-containing liquid from the buffer tank to the liquid delivering unit such that, if the producing unit stops operating, an ultrafine bubble-containing liquid accumulated in the buffer tank is delivered to the liquid delivering unit to enable the liquid delivering unit to deliver the ultrafine bubble-containing liquid to the outside.