A modular radio-labeling tracer synthesizer system comprising a housing having a plurality of slots containing syringe actuators. Each syringe actuator including a syringe holder, a syringe driver for driving a syringe plunger in a loading and/or dispensing direction. The unit is capable of adopting multiple configurations and is fully programmable and provides enhanced flexibility in development of novel radiotracers.

The present disclosure provides a process for making trifluoroacetyl iodide (TFAI) in a liquid phase reaction. Specifically, the present disclosure provides a liquid phase reaction of trifluoroacetyl chloride (TFAC) and hydrogen iodide (HI), with or without a catalyst, to form trifluoroacetyl iodide (TFAI). The reaction may be performed at ambient or elevated temperatures.

The present disclosure relates to a volume tailorable manufacturing system for quality assured manufacturing of biosafety level classified biopharmaceutical products and a method for tailoring a production volume capability of a manufacturing system. The volume tailorable manufacturing system comprises one or more multi-product suites and a control facility configured to control a unidirectional flow in a circulation system of the one or more multi-product suites. The circulation system is configured to interconnect the one or more multi-product suites and comprises separated supply and return systems. The supply system comprising at least one inlet, the return system comprising at least one outlet that is paired with the inlet and provided at a spatially predetermined position from the inlet, and each inlet/outlet pair comprises a seal when not connected to an adjacent multi-product suite.

Novel methods and means for convergent nanofabrication and nanoassembly are disclosed, and systems produced by and performing same are targeted at a broad range of applications. Molecules and/or nanostructures are bound to supported binding means and manipulated to translate such precursors or intermediates to bond together in precisely desired locations and orientations to yield desired precise structures. Methods and means suitable for precise fabrication of a range of materials including diamond, Beta-Silicon-Carbide and related materials, and precise modifications thereof such as color centers in predetermined configuration for quantum computation and information processing and storage applications, and for precise fabrication of halite structured materials including MgO, MgS, TiC, VN, ScN, precisely Mn doped ScN, NbN, HfC, TaC, HfxTayC, AbOS, SrO, BaO, Zr02, ZrC, ZrN, HfN, and also metals including refractory metals such as W are disclosed, yielding an extremely broad range of materials and materials properties which may be availed or utilized.

Aspects of the present invention provide a modular reactor device having an outer housing, and a plurality of components contained within the outer housing, the components including: a reaction chamber; a fluid pathway connected to the reaction chamber; and a valve arranged to control flow of fluid within the device, wherein the outer housing has a plurality of connection ports providing connections from the exterior of the device to the interior, the connection ports including: a fluid input and a fluid output; an electrical input; and a pneumatic input; wherein either the electrical input or the pneumatic input is connected to the valve to provide for control of the valve, and either the fluid input or the fluid output is connected to the reaction chamber or the fluid pathway. Other aspects provide a base station for receiving and controlling a modular reactor device and methods for manufacturing the modular reactor device and for performing reactions using a modular reactor device.

Systems, methods, and devices for generating radionuclides for use in production of radiopharmaceuticals; synthesizing the radionuclides generated and removing any unwanted products; measuring the quantity and activity level of the synthesized radionuclides; distributively delivering the radionuclides in appropriate quantities to modular cassette synthesis units in a modular cassette subsystem for contemporaneous/parallel production of radiopharmaceutical output and that allow reuse and/or quick, safe, and disposable replacement of portions of the subsystem; delivering non-radionuclide components to the modular cassette synthesis units as part of production of radiopharmaceutical output; measuring the quantity and activity level of each stream of radiopharmaceutical output; purifying the radiopharmaceutical output; dispensing individual doses in sterile vial(s); automatically producing labeling and dose related information; performing automated quality control on extracted samples of produced radiopharmaceutical output; and providing software and hardware controls for overall and sub-portion operation for optional remote data collection, communication, and/or control.

A device and method for producing a fluid product, such as a fluid reaction product, are provided. The device includes a reaction chamber and a reception chamber and a control unit configured to control the flow of fluid into the reaction chamber through the one or more fluid connections. The device also includes a first and second amount sensor arranged to determine an amount of fluidic component(s) of the reaction chamber and reception chamber continuously or at least quasi-continuously at least during the introduction of fluidic component(s).

Disclosed herein are cell processing systems, devices, and methods thereof. A system for cell processing may comprise a plurality of instruments each independently configured to perform one or more cell processing operations upon a cartridge, and a robot capable of moving the cartridge between each of the plurality of instruments.

Disclosed herein are cell processing systems, devices, and methods thereof. A system for cell processing may comprise a plurality of instruments each independently configured to perform one or more cell processing operations upon a cartridge, and a robot capable of moving the cartridge between each of the plurality of instruments.

A chemical synthesis device includes a reaction vessel, a waste liquid tank and an intermediate container. A chemical is supplied to the reaction vessel. The waste liquid tank is configured to hold waste liquid discharged from the reaction vessel. The intermediate container has a smaller capacity than the waste liquid tank. The intermediate container is provided between the reaction vessel and the waste liquid tank, via a waste liquid pipe. The pressure of the intermediate container is adjusted to adjust the flow supplied to the reaction vessel and the flow discharged from the reaction vessel.