Provided is a separating agent for optical isomers, which is excellent in solvent resistance and has optical separating ability comparable to or higher than that of existing separating agents for optical isomers of chemical bonding type or physical adsorption type. In the separating agent for optical isomers, amylose (3-chloro-5-methylphenylcarbamate) is supported on a carrier through chemical bonding.

Provided are a novel amylose derivative which exhibits excellent optical isomer separability and which is suitable as an optical isomer separating agent; and an optical isomer separating agent containing the amylose derivative. A task is attained by an amylose derivative having a constituent unit represented by formula (I) below; In below formula (I), R.sup.1 is a substituent group represented by any of formulae 1 to 3 below, and R.sup.2 is a substituent group represented by any of formulae a to g below. R.sup.1 and R.sup.2 are different substituent groups. A combination of R.sup.1 and R.sup.2 in which R.sup.1 is a substituent group represented by structural formula 3 and R.sup.2 is a substituent group represented by structural formula c is excluded from the formula (I).

##STR00001##

Provided are a novel amylose derivative which exhibits excellent optical isomer separability and which is suitable as an optical isomer separating agent; and an optical isomer separating agent containing the amylose derivative. A task is attained by an amylose derivative having a constituent unit represented by formula (I) below; In below formula (I), R.sup.1 is a substituent group represented by any of formulae 1 to 3 below, and R.sup.2 is a substituent group represented by any of formulae a to g below. R.sup.1 and R.sup.2 are different substituent groups. A combination of R.sup.1 and R.sup.2 in which R.sup.1 is a substituent group represented by structural formula 3 and R.sup.2 is a substituent group represented by structural formula c is excluded from the formula (I).

##STR00001##

Provided are a novel amylose derivative which exhibits excellent optical isomer separability and which is suitable as an optical isomer separating agent; and an optical isomer separating agent containing the amylose derivative. A task is attained by an amylose derivative having a constituent unit represented by formula (I) below; In below formula (I), R.sup.1 is a substituent group represented by any of formulae 1 to 3 below, and R.sup.2 is a substituent group represented by any of formulae a to g below. R.sup.1 and R.sup.2 are different substituent groups. A combination of R.sup.1 and R.sup.2 in which R.sup.1 is a substituent group represented by structural formula 3 and R.sup.2 is a substituent group represented by structural formula c is excluded from the formula (I). ##STR00001##

Provided are a novel amylose derivative which exhibits excellent optical isomer separability and which is suitable as an optical isomer separating agent; and an optical isomer separating agent containing the amylose derivative. A task is attained by an amylose derivative having a constituent unit represented by formula (I) below; In below formula (I), R.sup.1 is a substituent group represented by any of formulae 1 to 3 below, and R.sup.2 is a substituent group represented by any of formulae a to g below. R.sup.1 and R.sup.2 are different substituent groups. A combination of R.sup.1 and R.sup.2 in which R.sup.1 is a substituent group represented by structural formula 3 and R.sup.2 is a substituent group represented by structural formula c is excluded from the formula (I). ##STR00001##

The present invention relates to superficially porous particles (SPPs), also called core-shell, porous shell or fused core particles, which are state-of-the-art support materials used in the production of HPLC columns. Hydrolytically stable, highly selective superficially porous particle (SPP) hydrophilic interaction liquid chromatographic (HILIC) stationary phases having higher efficiencies and shorter retention times than analogous stationary phases on fully porous particles (FPP) is provided.

The present invention relates to superficially porous particles (SPPs), also called core-shell, porous shell or fused core particles, which are state-of-the-art support materials used in the production of HPLC columns. Hydrolytically stable, highly selective superficially porous particle (SPP) hydrophilic interaction liquid chromatographic (HILIC) stationary phases having higher efficiencies and shorter retention times than analogous stationary phases on fully porous particles (FPP) is provided.

The present invention relates to a novel stationary phase support for liquid chromatographic chiral separations. The specific combination of the special underlying support material and certain classes of known chiral selectors according to the invention produces far superior chiral (enantiomeric) separations than those obtained on any conventionally known supports. These chiral (enantiomeric) separations are enhanced in terms of significantly higher efficiencies (theoretical plate numbers), higher resolutions (R.sub.s), shorter retention times and either equivalent or slightly higher selectivities than those obtained on conventional supports.

The present invention relates to a novel stationary phase support for liquid chromatographic chiral separations. The specific combination of the special underlying support material and certain classes of known chiral selectors according to the invention produces far superior chiral (enantiomeric) separations than those obtained on any conventionally known supports. These chiral (enantiomeric) separations are enhanced in terms of significantly higher efficiencies (theoretical plate numbers), higher resolutions (R.sub.s), shorter retention times and either equivalent or slightly higher selectivities than those obtained on conventional supports.

A TLC plate allows the separation and detection of target substances on one plate. The TLC plate is made up of a substrate, a separating medium layer stacked on the substrate, and a permeation layer discontinuously stacked on the separating medium layer and allows the permeation of a target substance separated in the separating medium layer, wherein the separating medium layer has a separating property for the target substance and an optical responsiveness for ultraviolet rays, and the permeation layer has an optical responsiveness different from that of the separating medium layer.