A chromatographic material including a substrate having a surface and having a polymeric layer covalently bound to the surface; the polymeric layer comprising polymer molecules covalently attached to the surface of the substrate, each polymer molecule being attached to the surface via multiple siloxane bonds and each polymer molecule being connected to one or more functionalizing compounds that each comprise a functional group, wherein the polymeric layer is formed by covalently attaching polymer molecules to the surface of the substrate via multiple siloxane bonds, each polymer molecule containing multiple first reactive groups, and reacting the first reactive groups of the attached polymer molecules with at least one functionalizing compound that comprises a second reactive group that is reactive with the first reactive groups and that further comprises a functional group. Preferred conditions of reacting the polymer with the substrate include elevated temperature and reduced pressure.

The present invention relates to an improved diatomaceous earth composition containing salt water. The diatomaceous earth composition according to the present invention comprises an agglomerated mixture of calcined diatomaceous earth particles, water and at least one inorganic salt, wherein the mass ratio of the calcined diatomaceous earth particles and water is in the range of 1:1.0 to 1:2.0, and wherein the content of the at least one inorganic salt is equal to or more than 0.25 parts by mass based on 100 parts by mass of water. In a further aspect, the present invention relates to a method for producing the diatomaceous earth composition according to the present invention. In another aspect, the present invention relates to the use of the diatomaceous earth composition according to the present invention as an agent for precoat filtration or dynamic body feed filtration in biopharmaceutical applications.

Provided is a particulate alkaline earth metal ion adsorbent having a large adsorption capacity. The particulate alkaline earth metal ion adsorbent comprising: a potassium hydrogen dititanate hydrate represented by a chemical formula K.sub.2-xH.sub.xO.Math.2TiO.sub.2.Math.nH.sub.2O, wherein x is 0.5 or more and 1.3 or less, and n is greater than 0; and no binder, wherein the particulate alkaline earth metal ion adsorbent has a particle size range of 150 μm or more and 1000 μm or less.

Methods of producing and isolating .sup.68Ga, .sup.89Zr, .sup.64Cu, .sup.63Zn, .sup.86Y, .sup.61Cu, .sup.99mTc, .sup.45Ti, .sup.13N, .sup.52Mn, or .sup.44Sc and solution targets for use in the methods are disclosed. The methods of producing .sup.68Ga, .sup.89Zr, .sup.64Cu, .sup.63Zn, .sup.86Y, .sup.61Cu, .sup.99mTc, .sup.45Ti, .sup.13N, .sup.52Mn, or .sup.44Sc include irradiating a closed target system with a proton beam. The system can include a solution target. The methods of producing isolated .sup.68Ga, .sup.89Zr, .sup.64Cu, .sup.63Zn, .sup.86Y, .sup.61Cu, .sup.99mTc, .sup.45Ti, .sup.52Mn, or .sup.44Sc further include isolating .sup.68Ga, .sup.89Zr, .sup.64Cu, .sup.63Zn, .sup.86Y, .sup.61Cu, .sup.99mTc, .sup.45Ti, .sup.52Mn, or .sup.44Sc by ion exchange chromatography. An example target includes a target body including a target cavity for receiving the target material; a housing defining a passageway for directing a particle beam at the target cavity; a target window for covering an opening of the target cavity; and a coolant gas flow path disposed in the passageway upstream of the target window.

A Molybdenum/Technetium 99-m generator containing a metal-molybdate containing powder and an alumina sorbent. A preferred alumina sorbent is a gamma-phase alumina (γ-Al.sub.2O.sub.3), a chi-phase alumina (χ-Al.sub.2O.sub.3), or a combination thereof.

The present disclosure relates to a carrier with high capacity which is capable of adsorbing a chlorine dioxide gas at high concentration and a method of preparing a release kit which is capable of releasing the chlorine dioxide gas at a certain concentration for a long period of time, and more particularly, provides a preparation method of a carrier which is capable of adsorbing a high concentration chlorine dioxide gas at high capacity and capable of maintaining a physically and chemically stable state for a long period of time, the carrier including a silica gel, i.e., an indicator material which may indicate whether or not the chlorine dioxide gas is adsorbed or desorbed, by colors; and the present disclosure provides a method capable of manufacturing a chlorine dioxide gas sterilization device which consists of a release kit enabling the chlorine dioxide gas of a certain concentration to be continuously released from the carrier for a long period of time, an internal configuration of the kit including a well-light shielded sealed container capable of storing the carrier and the indicator, an inner upper part of the sealed container containing an aromatic gel that is capable of suppressing a distinctive smell of chlorine dioxide and immersed in a super absorbent polymer, which is configured so that the release amount and the release duration can be adjusted when adjusting the hole size by forming a hole with a predetermined size in a lid of the sealed container so that the chlorine dioxide gas can be released at a certain concentration from the inside of the sealed container to the outside thereof for a long period of time, and which not only can be subminiaturized by allowing the configuration of the device to become structurally very simple when applying the kit to the sterilization device, but also is more safe and inexpensive by excluding the use of harmful chemical substances, i.e., raw materials required for generating the chlorine dioxide gas. Further, as a carrier according to the present disclosure may be reusable up to five times, the carrier has great advantages in terms of recycling of resources and maintenance costs.

The present invention provides: a porous fiber that exhibits both improved adsorption capacity, and suppressed exposure and detachment of particulates; an adsorption column filled with said porous fiber; and a blood purification system in which an adsorption column is connected to a water removal column. The porous fiber according to the present invention has a three-dimensional pore structure formed by a solid fiber, and satisfies all of the following conditions. (1) The porous fiber has particulates having a diameter of not more than 200 μm, and the percentage of area occupied by said particulates having a diameter of not more than 200 μm in a horizontal cross section of the three-dimensional pore structure is at least 3.0%. (2) The porous fiber does not contain said particulates having a diameter of not more than 200 μm in the region within 1.0 μm in the depth direction from the outermost surface.

A portable breathing apparatus for oxygen enrichment of breathable air comprises: an adsorption vessel; an air compressor for pumping air into the adsorption vessel; a valve for purging pressure from the adsorption vessel; an adsorbent disposed within the adsorption vessel adsorbing a non-oxygen constituent of air when the vessel is pressurized, thereby producing oxygen-enriched air, and desorbing the non-oxygen constituent when the pressure is purged.

A chromatographic material including a substrate having a surface and having a polymeric layer covalently bound to the surface; the polymeric layer comprising polymer molecules covalently attached to the surface of the substrate, each polymer molecule being attached to the surface via multiple siloxane bonds and each polymer molecule being connected to one or more functionalizing compounds that each comprise a functional group, wherein the polymeric layer is formed by covalently attaching polymer molecules to the surface of the substrate via multiple siloxane bonds, each polymer molecule containing multiple first reactive groups, and reacting the first reactive groups of the attached polymer molecules with at least one functionalizing compound that comprises a second reactive group that is reactive with the first reactive groups and that further comprises a functional group. Preferred conditions of reacting the polymer with the substrate include elevated temperature and reduced pressure.

The present invention provides a functionalised polymeric chromatography medium, prepared by a process which comprises (i) providing a substrate formed of one or more polymer nanofibres, (ii) grafting one or more neutral polymer chains from the substrate, and (iii) contacting the grafted product with a reagent which functionalises the product of step (ii) as a chromatography medium, wherein step (ii) comprises reacting a plurality of compounds of formula and/or its enantiomers, and/or its derivatives of formula (I) and/or enantiomers and/or diastereomers thereof: with one or more functional groups present on the nanofibre substrate, wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 may be the same or different, and are chosen from H, halogen, C.sub.1-C.sub.4 alkyl, or C.sub.1-C.sub.4 alkoxy provided that at least one of R.sub.1, R.sub.2, R.sub.3, R.sub.4 or R.sub.5 is not hydrogen. ##STR00001##