B01J47/022

METHOD FOR PRODUCING ULTRAPURE WATER, ULTRAPURE WATER PRODUCTION SYSTEM, AND ION EXCHANGER-FILLED MODULE
20210246050 · 2021-08-12 · ·

Provided is a method for producing ultrapure water to supply, to a use point, ultrapure water obtained by treating raw material water for ultrapure water production in an ultrapure water production apparatus, wherein the raw material water for ultrapure water production contains at least one or more elements selected from B, As, Al, Ti, Cr, Fe, Cu, Zn, Sn, V, Ga, and Pb, and wherein an ion exchanger-filled module filled with at least a monolithic organic porous anion exchanger is installed in a treatment path of the ultrapure water production apparatus or in a transfer path from the ultrapure water production apparatus to the use point, and water to be treated is passed through the ion exchanger-filled module for treatment.

Scalable purification method for AAV1

A two-step chromatography purification scheme is described which selectively captures and isolates the genome-containing rAAV vector particles from the clarified, concentrated supernatant of a rAAV production cell culture. The process utilizes an affinity capture method performed at a high salt concentration followed by an anion exchange resin method performed at high pH to provide rAAV vector particles which are substantially free of rAAV intermediates.

Scalable purification method for AAV1

A two-step chromatography purification scheme is described which selectively captures and isolates the genome-containing rAAV vector particles from the clarified, concentrated supernatant of a rAAV production cell culture. The process utilizes an affinity capture method performed at a high salt concentration followed by an anion exchange resin method performed at high pH to provide rAAV vector particles which are substantially free of rAAV intermediates.

Ion exchange resin transportation and storage

Methods of stabilizing virgin ion exchange resin material are provided. The methods include rinsing virgin ion exchange resin material with deoxygenated water, introducing the rinsed virgin ion exchange resin material into a liquid impermeable compartment of a gas impermeable vessel and hermetically sealing the vessel. The methods include rinsing virgin ion exchange resin material with deoxygenated water, introducing the rinsed virgin ion exchange resin material into a gas impermeable vessel, introducing an oxygen scavenging material into the gas impermeable vessel, and hermetically sealing the vessel. A method of facilitating water treatment in a site in need thereof by providing rinsed virgin ion exchange resin material in deoxygenated water positioned in a liquid impermeable compartment of a gas impermeable vessel is also provided. A vessel containing deoxygenated water and virgin ion exchange resin material and an oxygen scavenging material is also provided.

Ion exchange resin transportation and storage

Methods of stabilizing virgin ion exchange resin material are provided. The methods include rinsing virgin ion exchange resin material with deoxygenated water, introducing the rinsed virgin ion exchange resin material into a liquid impermeable compartment of a gas impermeable vessel and hermetically sealing the vessel. The methods include rinsing virgin ion exchange resin material with deoxygenated water, introducing the rinsed virgin ion exchange resin material into a gas impermeable vessel, introducing an oxygen scavenging material into the gas impermeable vessel, and hermetically sealing the vessel. A method of facilitating water treatment in a site in need thereof by providing rinsed virgin ion exchange resin material in deoxygenated water positioned in a liquid impermeable compartment of a gas impermeable vessel is also provided. A vessel containing deoxygenated water and virgin ion exchange resin material and an oxygen scavenging material is also provided.

Longitudinal Gradient Chromatography Columns
20210129128 · 2021-05-06 ·

An ion exchange chromatography column contains an ion exchange stationary phase that includes a charged substrate, a plurality of first particles, and a plurality of second particles. The plurality of first particles each include first ion exchange groups and the first particles are ionically bound to the charged substrate. The plurality of second particles each include second ion exchange groups and the second particles are ionically bound to the charged substrate. The first particles having a first ion exchange group density, and the second particles having a second ion exchange group density. The first ion exchange group density is greater than the second ion exchange group density. The ion exchange chromatography column has a number of zones connected in series where each zone can have a varying level of first ion exchange groups and second ion exchange group from the inlet zone to the outlet zone.

Longitudinal Gradient Chromatography Columns
20210129128 · 2021-05-06 ·

An ion exchange chromatography column contains an ion exchange stationary phase that includes a charged substrate, a plurality of first particles, and a plurality of second particles. The plurality of first particles each include first ion exchange groups and the first particles are ionically bound to the charged substrate. The plurality of second particles each include second ion exchange groups and the second particles are ionically bound to the charged substrate. The first particles having a first ion exchange group density, and the second particles having a second ion exchange group density. The first ion exchange group density is greater than the second ion exchange group density. The ion exchange chromatography column has a number of zones connected in series where each zone can have a varying level of first ion exchange groups and second ion exchange group from the inlet zone to the outlet zone.

ION EXCHANGE REACTOR WITH PARTICLE TRAPS FOR LITHIUM EXTRACTION
20210077990 · 2021-03-18 ·

The present invention relates to the extraction of lithium from liquid resources such as natural and synthetic brines, leachate solutions from clays and minerals, and recycled products. For the extraction of lithium from the liquid resources, an ion exchange reactor has a tank, ion exchange particles, particle traps, and provision to modulate pH of the liquid resource.

ION EXCHANGE REACTOR WITH PARTICLE TRAPS FOR LITHIUM EXTRACTION
20210077990 · 2021-03-18 ·

The present invention relates to the extraction of lithium from liquid resources such as natural and synthetic brines, leachate solutions from clays and minerals, and recycled products. For the extraction of lithium from the liquid resources, an ion exchange reactor has a tank, ion exchange particles, particle traps, and provision to modulate pH of the liquid resource.

Highly porous lubricant conditioning and remediation media
10926243 · 2021-02-23 · ·

The present invention is a solid lubricant treatment medium, usually but not always in bead form, suitable to be brought into contact with lubricants to remediate and to condition them. A key feature of the medium, typically a polymeric resin, is the presence of relatively very large pores, which are able to capture and remove fine lubricant contaminants and breakdown products (such as small phosphate ester varnish, soot, coke, dissolved metal or other small semi-soluble or insoluble particles). Resins and adsorbents of the prior art have proven unable to remove fine contaminants like phosphate ester varnish that have a deleterious impact on industrial equipment performance and reliability. The mean pore size diameter of the medium is between about 8,000 and 100,000 and, more preferably, in the range of about 20,000 to about 80,000 .