The present invention relates to a system for reducing a content of 5-hydroxymethylfurfural in a high fructose syrup, including an ion exchange positive column and an ion exchange negative column for performing cation and anion removals in sequence for an F42 high fructose syrup obtained by performing isomerization and first decolorization, a heat exchanger for performing heat exchange and temperature reduction for an F55 high fructose syrup obtained by performing concentration, chromatographic separation, blending and second decolorization in sequence for the F42 high fructose syrup subjected to ion exchange, a mixed bed column for performing purification for the heat-exchanged F55 high fructose syrup, and an evaporation tank for performing concentration for the F55 high fructose syrup subjected to mixed bed treatment. The present invention further provides a method of reducing a content of 5-hydroxymethylfurfural in a high fructose syrup. In the present invention, optimization is performed for ion exchange and operation modes and parameters of the mixed bed such that the HMF content in the high fructose syrup product is reduced in a case of ensuring the quality of the high fructose syrup product, thus improving the quality of the high fructose syrup product.

The present invention relates to a system for reducing a content of 5-hydroxymethylfurfural in a high fructose syrup, including an ion exchange positive column and an ion exchange negative column for performing cation and anion removals in sequence for an F42 high fructose syrup obtained by performing isomerization and first decolorization, a heat exchanger for performing heat exchange and temperature reduction for an F55 high fructose syrup obtained by performing concentration, chromatographic separation, blending and second decolorization in sequence for the F42 high fructose syrup subjected to ion exchange, a mixed bed column for performing purification for the heat-exchanged F55 high fructose syrup, and an evaporation tank for performing concentration for the F55 high fructose syrup subjected to mixed bed treatment. The present invention further provides a method of reducing a content of 5-hydroxymethylfurfural in a high fructose syrup. In the present invention, optimization is performed for ion exchange and operation modes and parameters of the mixed bed such that the HMF content in the high fructose syrup product is reduced in a case of ensuring the quality of the high fructose syrup product, thus improving the quality of the high fructose syrup product.

A purification method for separating and purifying an organic solvent from a liquid mixture of an organic solvent and water, the organic solvent having a boiling point of more than 100 C. at 1 atm, includes the steps of: passing the liquid mixture through a first ion exchange device; supplying the liquid mixture discharged from the first ion exchange device to a pervaporation device to selectively separate water component; supplying the organic solvent recovered from the concentration side of the pervaporation device to an evaporator to obtain a purified organic solvent; and passing, through the second ion exchange device, a portion of liquid containing the organic solvent and flowing at a first position subsequent to the first ion exchange device. The liquid discharged from the second ion exchange device is returned to a second position which is at a preceding stage of the pervaporation device.

A purification method for separating and purifying an organic solvent from a liquid mixture of an organic solvent and water, the organic solvent having a boiling point of more than 100 C. at 1 atm, includes the steps of: passing the liquid mixture through a first ion exchange device; supplying the liquid mixture discharged from the first ion exchange device to a pervaporation device to selectively separate water component; supplying the organic solvent recovered from the concentration side of the pervaporation device to an evaporator to obtain a purified organic solvent; and passing, through the second ion exchange device, a portion of liquid containing the organic solvent and flowing at a first position subsequent to the first ion exchange device. The liquid discharged from the second ion exchange device is returned to a second position which is at a preceding stage of the pervaporation device.

The invention relates to a sorbent for removing metabolic waste products from a dialysis liquid, the sorbent comprising a soluble source of sodium ions. The sorbent comprises an ion exchange system which converts urea to ammonium ions and which is configured to exchange ammonium ions for predominantly hydrogen ions and to exchange Ca, Mg, and K for predominantly sodium ions. The soluble source of sodium ions overcomes an initial drop in sodium concentration in regenerated dialysate. When used in conjunction with an infusion system configured to utilise exchange of Ca, Mg and K for sodium during dialysate regeneration a desired sodium ion concentration can be maintained.

The invention relates to a sorbent for removing metabolic waste products from a dialysis liquid, the sorbent comprising a soluble source of sodium ions. The sorbent comprises an ion exchange system which converts urea to ammonium ions and which is configured to exchange ammonium ions for predominantly hydrogen ions and to exchange Ca, Mg, and K for predominantly sodium ions. The soluble source of sodium ions overcomes an initial drop in sodium concentration in regenerated dialysate. When used in conjunction with an infusion system configured to utilise exchange of Ca, Mg and K for sodium during dialysate regeneration a desired sodium ion concentration can be maintained.

Sorbent cartridges having an improved shelf life comprising multiple layers of sorbent materials wherein moisture levels in the multiple layers of sorbent materials are controlled, and wherein a first layer of the sorbent cartridge comprises activated carbon and a second layer in direct contact with the first layer comprises one or both of hydrous zirconium oxide and zirconium phosphate.

Sorbent cartridges having an improved shelf life comprising multiple layers of sorbent materials wherein moisture levels in the multiple layers of sorbent materials are controlled, and wherein a first layer of the sorbent cartridge comprises activated carbon and a second layer in direct contact with the first layer comprises one or both of hydrous zirconium oxide and zirconium phosphate.

Disclosed is a microfluidic system having a housing and having at least one flow channel formed within the housing, wherein at least one element that has an ion exchanger mixed-bed resin is arranged in at least one sub-region of the flow channel, and at least the flow channel is formed from a porous material, wherein the ion exchanger mixed-bed resin is intended, by way of its anion and cation exchanger properties, to reduce the ion concentration of a salt or of a contaminating compound of a fluid medium that has macromolecular compounds and/or cellular structures.

A process for purifying (i) a hydrophilic organic solvent, (ii) a hydrolysable organic solvent, or (iii) a mixture of a hydrophilic organic solvent and a hydrolysable organic solvent by removing ionic contaminants from the hydrophilic organic solvent, from the hydrolysable organic solvent, or from the mixture of a hydrophilic and a hydrolysable organic solvent without generation of by-product impurities, the process including the steps of contacting the hydrophilic organic solvent, the hydrolysable organic solvent, or the mixture of hydrophilic and hydrolysable organic solvents with a mixed bed of ion exchange resin; wherein the mixed bed of ion exchange resin includes a mixture of: (a) a weak-acid cationic ion exchange resin and (b) a weak-base anionic ion exchange resin.