A capillary column includes a fused silica tubing and a polyimide coating over the fusing silica tubing. Additionally, the capillary column further includes a first plurality of integrated ferrules positioned along at least a first portion of the fused silica tubing and spaced apart from one another by a first fixed interval.

A capillary column includes a fused silica tubing and a polyimide coating over the fusing silica tubing. Additionally, the capillary column further includes a first plurality of integrated ferrules positioned along at least a first portion of the fused silica tubing and spaced apart from one another by a first fixed interval.

The present invention provides a lipid extraction device comprising a capillary tube, wherein the capillary tube comprises a first region containing a first filler; and a second region present in a region other than the first region and containing a second filler having polarity different from the first filler. The present invention also provides a system and a method for extracting and analyzing lipids from a biological sample using the lipid extraction device.

A curtain airbag device mounting structure includes: a first pillar forming a part of a front pillar and extends substantially along a vehicle height direction; a second pillar forming another part of the front pillar, the second pillar being disposed on a rear side of a vehicle relative to the first pillar at a predetermined distance from the first pillar and extending substantially along the vehicle height direction; a transparent member bridged between the first pillar and the second pillar; and a curtain airbag device including a curtain airbag stored along a roof side rail and the second pillar, the curtain airbag being configured to inflate and deploy in a curtain-like fashion over a side portion of a cabin of the vehicle in case of a collision of the vehicle.

A capillary column includes a fused silica tubing and a polyimide coating over the fusing silica tubing. Additionally, the capillary column further includes a first plurality of integrated ferrules positioned along at least a first portion of the fused silica tubing and spaced apart from one another by a first fixed interval.

The present invention relates generally to a sample processing device, such as a microfluidic device, comprising a substrate, wherein the substrate comprises a plurality of channels configured to transport a fluid, and wherein the plurality of channels are substantially coated with lubricin, or a functional variant thereof. Also disclosed herein are methods of manufacturing such devices, methods of preventing fouling of a channel in a device using lubricin, or a functional variant thereof and methods of controlling the electrokinetic flow of an analyte through a channel that is substantially coated with lubricin, or a functional variant thereof. Also disclosed herein is chromatographic material for the electrophoretic and/or chromatographic separation of an analyte, wherein the chromatographic material is substantially coated with lubricin, or a functional variant thereof.

The chromatographic column is a stainless steel column having a stationary phase of porous monolithic polymer chemically bonded to the interior wall of the stainless steel column so that the stationary phase is fixed and immobile and does not require frits or other seals to retain particulate matter or a slurry in the column. The inner wall of the column is oxidized and then vinylized with a difunctional linker to chemically bond the polymer to the column. The difunctional linker may be 3-(trimethoxysilyl) propyl methacrylate, vinyl trimethoxysilane, 3-mercaptopropyl trimethoxysilane, or glycidoxypropyltrimethoxysilane. The monolithic polymer is prepared in situ in the column by radical polymerization of a monovinyl monomer with a crosslinking divinyl monomer. The column may be a conventional stainless steel column (? inner diameter), capillary micro-LC ( 1/16), or nan-LC (( 1/32).

The invention relates to a monolithic porous material made of amorphous silica or activated alumina, comprising substantially rectilinear capillary channels that are parallel to one another, wherein: the channels have a substantially uniform cross-section relative to each other, the cross-section of each channel is regular over its entire length, the channels pass through the material from end to end, the length of the channels is equal to or more than 10 mm. The invention also relates to an annular, radial or axial chromatographic apparatus, the packing of which consists of at least one said monolithic material. The invention also relates to processes for manufacturing such a monolithic material.

The invention relates to a chromatography method in which a gaseous, liquid or supercritical mobile phase containing species to be separated is circulated through a packing, said packing comprising: a plurality of capillary ducts extending in the packing between an upstream face through which the mobile phase enters the packing and a downstream face through which the mobile phase leaves the packing, and a continuous medium permeable to molecular diffusion extending between said ducts, comprising a porous organic gel or an organic liquid and including at least one network of connected pores, the size of which is greater than two times the molecular diameter of at least one species to be separated and opening to the ducts, so as to give said at least one species a diffusive path between said ducts. The invention also relates to a packing for the implementation of such a method and a method for manufacturing such a packing.

Surface-modified silica microparticles that are functionalized with stabilized phospholipid vesicles are described herein. These stabilized vesicles can be functionalized with either transmembrane receptors or membrane associated receptors and used for affinity pull-down assays or other chromatographic separation modalities to provide affinity capture/concentration of low abundance ligands in complex mixtures with minimal sample preparation. Further described are methods and apparatus for forming polymer frits in a fused silica capillary. The capillary containing a monomer solution is placed between one or more heat sources connected to each other via a jig and operatively coupled to a temperature controller. The polymer frits are synthesized via thermal polymerization of the monomer solution using the heat sources, which allows for placement of the polymer frits at a spatially-defined location in the capillary.