The present invention is directed generally to devices and methods for manipulating laboratory pipettes in a programmable manner. The present invention is directed to an apparatus and methods for allowing a user to instruct the device to perform a specific process; identifying the type, location and identity of the consumables to be used; manipulating a plurality of pipettes for performing the liquid handling; monitoring the process during and after its execution; generating a detailed report for the plurality of actions. Other aspects of this invention include optimization of the liquid dispensing performances of a pipette; monitoring and controlling individual actions by means of vision; virtualization of the protocol definition by means of a reality augmented software interface; integration of the system in a conventional laboratory environment workflow.

The invention relates to a pipetting device for automatic analysis instruments and a method for heating a volume of liquid in a heated pipetting needle.

Nanoliter pipette assembly. The assembly includes a housing containing a working fluid in a working fluid chamber therein and includes a moveable piston within the housing, the piston moveable by a linear actuation mechanism for contact with the working fluid. A tip portion is provided that includes a diaphragm deformable to engage an inner portion of the tip. It is preferred that the diaphragm have a projecting three-dimensional structure for direct contact with a liquid.

This invention is related to high-throughput screening field, in particular to an application method for automatic micro droplet array screening system of picoliter scale precision. According to this invention, the fluid driving system and the capillary are fully filled with fluid of low thermal expansion coefficient as the carrier fluid to thoroughly empty air bubbles in the capillary; after that, immersing the sampling end of capillary into the oil phase that is mutually immiscible with aqueous sample to aspirate a section of oil phase into the capillary for isolation of aqueous sample and carrier fluid; once completed, immersing the sampling end of capillary into the sample/reagent storage tube to aspirate a certain volume of aqueous sample into the capillary; finally, moving the sampling end of capillary to the oil phase above microwells on microwell array chip, and pushing the sample solution in the capillary into microwells to form sample droplet. Quantitative metering of fluid and droplet generation according to this invention are provided with volume precision in picoliter, which can effectively minimize the consumption of sample/reagent, and save the testing cost during high-throughput screening.

The present invention relates to a coupling formation of a pipetting channel of a pipetting device for coupling of an implement, for instance a pipette tip, or a laboratory instrument, laboratory tool or the like, thereto, wherein the coupling formation surrounds a pipetting channel section which extends along a pipetting channel axis which defines an axial direction, wherein the coupling formation additionally has, at its free longitudinal end, a pressure-imparting orifice into which the pipetting channel section opens and has, at its radially outer surface which surrounds the pipetting channel axis and extends principally in axial direction and in peripheral direction about the pipetting channel axis relative to the pipetting channel axis, a coupling projection which yields in the radial direction, which is characterized in that the coupling projection is provided so as to be essentially undeformable but radially movable on a spring arrangement which is elastic in radial direction.

There is provided a bellows type dispensing tip, a bellows type dispensing apparatus, and a method of bellows type dispensing processing that performs highly precise dispensing processing despite having a simple structure. The apparatus comprises; two or more bellows type dispensing tips having; an accommodating section that is capable of accommodating a liquid or gas in the interior thereof surrounded by a wall face, and that has a deformable deforming wall face in a portion of the wall face, and an opening section communicated with the accommodating section, through which the liquid to be suctioned/discharged can flow in and flow out due to expansion and contraction of the interior caused by deformation of the deforming wall face; and a dispensing head that supports the bellows type dispensing tips, and that performs suction/discharge of the liquid into or from the bellows type dispensing tip, by deforming the deforming wall face.

The invention relates to a pipetting apparatus for pipetting laboratory samples into a pipetting container which can be connected to the pipetting apparatus, which pipetting container is in particular designed according to the invention, comprising a container side and a first connection section, by means of which the pipetting container can be connected to the pipetting apparatus, and comprising an information carrying device with at least one information section, which carries information, on this container side; the pipetting apparatus comprising an electric information reading device, by means of which information contained on the information reading device can be read when the pipetting container is connected to the pipetting apparatus, and which comprises at least one electric sensor device, which comprises at least one sensor section, opposite to which a measuring space is formed, wherein the sensor device is configured to read the information content of at least one information section when the latter is arranged in the measuring space. The invention furthermore relates to the pipetting container or adapter element, which can be used with the pipetting apparatus, and a method for the production thereof.

This invention relates to methods, systems, and computer program products for verifying dispensing of a fluid from a pipette.

The present invention relates to a means for improving fluid exchange across a microplate, comprising a microplate which comprises one or more internal modifications which aid the introduction and removal of fluids from the wells of the plate and minimize the damage caused to biological matter located therein upon introduction or removal of a pipette tip and/or fluids, and/or a means for inclining the microplate at an angle from the horizontal and retaining the microplate in the inclined position, to facilitate fluid introduction and aspiration from the wells of the microplate.

A universal pipette that can serve as a standard pipette or as a capillary action pipette. A side tube emanates from a main tube in the pipette. The side tube comprises a through hole which is sealed with a through hole tab. The through hole tab can be broken off by a user, thereby removing the seal and exposing the through hole to outside of the pipette. Liquid can now easily be drawn into the tip of the pipette by virtue of capillary action which is now enabled do to the exposed through hole.