An immunoblotting instrument and a control method are provided. The immunoblotting instrument comprises an immunoblotting instrument body, and an immunoblotting instrument control device, an incubation device and a liquid feeding and sucking device that are provided on the immunoblotting instrument body, and further comprises a temperature control device for controlling the incubation environment temperature of the immunoblotting membrane. By setting the temperature control device in the immunoblotting instrument to control the temperature of the reaction environment between the immunoblotting membrane and the reagent, the immunoblotting membrane can contact and react with the reagent under the same and set environmental condition, so that the reliability of the final detection results can be improved; at the same time, each functional module is associated and controlled by the control device, so that the entire immunoblotting process is automatically completed, reducing manual intervention and improving work efficiency.

Since a detergent is a consumption article, it is desirable that a use amount of the detergent be as small as possible in a limit that the washing effect is not substantially reduced. Provided is an automatic analyzer which includes a syringe pump which is connected to a probe and performs the body aspiration and discharge, a feed pump which feeds washing water for washing the inside of the probe to the probe via the syringe pump and a controller which controls the dispensing mechanism and the syringe pump, in which the controller, in a case of washing the probe by sucking a detergent in the probe a plurality of times, controls the syringe pump so as to discharge the detergent after sucking the detergent and to suck the next detergent without feeding the washing water to the probe by the feed pump.

A first fluid handling device according to the present invention has: a first liquid introduction part; a first cleaning liquid introduction part; a first flow path through which a liquid introduced to the first liquid introduction part or to the first cleaning liquid introduction part flows; a second liquid introduction part; a second cleaning liquid introduction part; a second flow path through which a liquid introduced to the second liquid introduction part or to the second cleaning liquid introduction part flows; a third flow path which allows flowing therethrough of the liquid having flowed through the first flow path and the liquid having flowed through the second flow path; a first diaphragm valve that is disposed between the first and third flow paths; a second diaphragm valve that is disposed between the second and third flow paths; and a chamber that is connected to the third flow path.

Described here are systems and methods for a reusable, aseptic connector. A connector system provides aseptic fluid connection. The connector system has an inlet connector assembly having an inlet fluid passageway and an inlet valve configured to seal the inlet fluid passageway when in a disconnected state. The connector also has an outlet connector assembly having an outlet fluid passageway and an outlet valve configured to seal the outlet fluid passageway when in a disconnected state. The inlet valve is configured to couple to the outlet valve to form an aseptic fluid connection between the inlet and outlet fluid passageways when in a connected state.

Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use cartridge component configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site.

In an embodiment, the present disclosure pertains to a microfluidic device composed of a substrate having an inlet region and a first storage region, a fluid transporting channel in fluid communication with the inlet region, an expandable component in fluid communication with the fluid transporting channel and coupled to a movable arm, and a fluid transporting region coupled to the movable arm and operable to be moved in a horizontal direction to the fluid transporting channel to thereby form fluidic contact between the inlet region and the first storage region upon expansion of the expandable component. In an additional embodiment, the present disclosure pertains to a method of fluid flow utilizing a microfluidic device of the present disclosure.

An aseptic sampling apparatus includes an isolator, a liquid delivery port that is disposed in the isolator, a sampling section that is disposed inside the isolator, a first flow path that communicates with a discharge flow path of the sampling section, and that connects an inside and outside of the isolator to each other through the liquid delivery port, a fluid supplying unit that supplies a fluid to the sampling section, a gas supplying unit that communicates with the fluid supplying unit, and a seal member that prevents the fluid supplied from fluid supplying unit to the discharge flow path from leaking.

Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use cartridge component configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site.

A nucleic acid detection system according to an embodiment is a nucleic acid detection system to detect a target nucleic acid in a sample and includes a thermal inactivation chamber, an amplification chamber, and a detection chamber, all of which constitute a liquid flow path. In this system, liquid flows through the thermal inactivation chamber, the amplification chamber, and the detection chamber sequentially. The thermal inactivation chamber includes a reagent to thermally inactivate and decompose the sample. The amplification chamber includes a reagent to amplify the target nucleic acid. The detection chamber includes a test strip to conduct a Cas enzyme reaction with the target nucleic acid and a lateral flow detection.

An open microfluidic system is provided. The open microfluidic system including the extreme wettability of exclusive liquid repellency (ELR), open microchannels with high lateral resolution and low profile, various valve arrangements, capable of a broad range flow rates, and capable of spatially and temporally trapping particles in open fluid.