Patent classifications
B01L2200/023
SYRINGE HOUSING FOR PIPETTING A BIOLOGICAL MATERIAL, COMPRISING INTEGRATED MEMBRANES
A first aspect of the invention relates to a syringe housing which can have the following elements: a syringe body which has a first open end and a second open end, a first channel being formed between the two ends; a first membrane which is arranged such that the membrane extends substantially perpendicularly to the longitudinal direction of the first channel over the cross-section thereof; a syringe body attachment which has a first open end and a second open end, a second channel being formed between the two ends; a second membrane which is arranged such that the membrane extends substantially perpendicularly to the longitudinal direction of the second channel over the cross-section thereof; wherein the second open end of the syringe body and the first open end of the syringe body attachment are designed so as to be connectable in a formfitting manner and thus form the syringe housing, the first channel and the second channel form a continuous channel in the connected state of the syringe housing, and the first membrane and the second membrane define an extraction volume in the region of the continuous channel. Furthermore, different embodiments provide a pipette device which is designed for the automatic use of the syringe housing according to the invention.
System and processes for isolation and enrichment by magnetic separation
Systems and methods for handling a variety of sample and preparatory fluids in a rack specifically configured for compatibility with predetermined liquid handlers such as automated pipettors or multi-channel manual pipettors and set up for magnetic based sample preparation. The rack can hold all of the necessary sample and reagent vials, and present them to the pipettor in some embodiments in a way that allows for parallel operation. The rack includes slidable magnets that in some embodiments are actuatable directly by the pipettor, eliminating a layer of complexity. Combined with a suitable pipettor the magnet enabled rack supports a multistep magnetic based sample preparation capability in a high throughput manner at one station that enhances sample purity throughout magnetic separation processes.
Pipetting Device, Pipette Tip Coupler, and Pipette Tip: Devices and Methods
Pipette assembly comprising a pipette device, a pipette tip, and an expanding mandrel collet coupling device coupling the tip to the pipette device, the coupling device comprising: circumferentially spaced apart segments, an annular base disposed below the segments and comprising a distal portion, an elastomeric element circumscribing the distal portion, and upwardly extending circumferentially spaced apart arms attached at first ends to the annular base and having upper free ends each supporting a different one of the segments configured to expand between a first and a second greater circumference for engaging a first interior working surface of the tip in concurrence with the elastomeric element sealing against a second interior working surface below the first surface and in concurrence with an abutment between a disk exteriorly disposed about a medial portion of the arms and a stepped interior shoulder of the tip disposed between the first and second working surfaces.
Pipette block with molded piston chambers
The present invention relates to a pipette dispensing block with an improved design for the piston chambers. In a multichannel pipetting block with a grid or array of pipetting piston of any order, the individual piston chambers are individually manufactured using the injection molding process. The individual piston chambers are assembled into a grid or single line array and held together by upper and lower plates in combination with either stabilizing posts or walls. The piston chambers are designed and assembled with a dual o-ring design at the tip and a tip sealing gasket at the bottom to provide the air-tight seal that is required for optimum pipetting performance. When combined with pistons and a motor-driven lifting plate for the pistons, the entire assembly forms a forms a multichannel pipetting block
System for port and tube holder assembly attachment device
A tube holder assembly includes a base plate, an attachment plate, and an optional securing element. The base plate may include guides into which protrusions of the attachment plate slide to alter the positioning apparatus from an open position to a closed position. The base plate also includes receivers to receive tubular members, which have their movement restrained by the receivers and the securing elements in the closed position. The tube holder assembly may also include a latch to help maintain the closed position during operation.
Dynamic broad volumetric range pipette
Multivolume liquid pipettes with nested plunger and vacuum chamber configurations and methods of using such pipettes are disclosed herein. These pipettes typically include a body and a fluid displacement assembly with a small plunger element slideably received within a larger plunger element, each movable within a vacuum chamber for the precise and accurate control of the displacement of fluid, such as air. In turn, this allows for a single device to aspirate and dispense a broad range of liquids in a dynamic, accurate, and precise manner. In addition, the devices disclosed herein may also include a multi-tiered spring-loaded ejection mechanism to allow the user to use and eject pipette tips of different sizes.
False Bottom Specimen Transport Tube
A biological false bottom transport tube system includes a top section of a specimen tube body, the top section comprising a top, a semi-spherical interior floor, and a bottom below the interior floor, the top section manufactured from a material transparent to both visible and infrared light, wherein the top section may hold a sample on the interior floor; and a bottom section of the specimen tube body, the bottom section comprises a top of a diameter less than a dimeter defined by a remainder of the bottom section, the top of the bottom section fits into the bottom of the top section below the interior floor such that the top of the bottom section is secured within the bottom of the top section, the bottom section manufactured from a material that is not transparent to either visible or infrared light.
System and method for titrating liquids
A system for titrating liquids, with a syringe or tip, comprising a holding device and at least one tag and a metering equipment, comprising an additional holding device for holding the syringe or tip on the holding device, a reading device for reading the tag of the syringe or tip held by the additional holding device, a driving device having a motor, which is detachably coupled with a plunger of the syringe when the same is held by the additional holding device, or which is coupled with a plunger which is arranged in a cylinder which is coupled with the tip via a fluid conduit, when the same is held by the additional holding device, an operating device for operating the metering equipment and a control device, connected with the operating device, the reading device and the driving device, which controls the movement of the plunger depending of the tag of the inserted syringe or tip.
TEST TUBE HOLDING ASSEMBLY
A test tube holding assembly or test tube rack includes at least two test tube holders, where each test tube holder in turn defines a central longitudinal axis, two storage zones, and includes a connecting member. The connecting members permit coupling of the two test tube holders and rotation of the two coupled test tube holders about an axis parallel to the longitudinal axis of at least one of the test tube holders. The test tube holders are also positionable in multiple orientations, where each orientation at least partially determines which of the two storage zones are available to receive a test tube therein.
INTEGRATED CONSUMABLE DATA MANAGEMENT SYSTEM & PLATFORM
- Manish KOCHAR ,
- Peter J. Bosco ,
- Ian D. Chamberlin ,
- Bandele Jeffrey-Coker ,
- Eric M. Jones ,
- Gary I. KRIVOY ,
- Don E. KRUEGER ,
- Aaron H. LEIMKUEHLER ,
- Pei-Ming WU ,
- Kim-Xuan Nguyen ,
- Pankaj Oberoi ,
- Louis W. PANG ,
- Jennifer Parker ,
- Victor Pellicier ,
- Nicholas Sammons ,
- George Sigal ,
- Jacob N. Wohlstadter ,
- Michael L. VOCK ,
- Stanley T. Smith ,
- Carl C. Stevens ,
- Rodger D. Osborne ,
- Kenneth E. Page ,
- Michael T. WADE ,
- Jon Willoughby ,
- Lei WANG
The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.