B01L2200/0621

Microbiological testing device, method for provision and use of such a device

A microbiological testing device for testing a liquid to be analysed that is liable to contain at least one microorganism, includes a closed inner space, a microbiological filtration member and an inlet port. The device has a nutritive layer in contact with the filtration member, and in that, in a configuration for providing the device an open/close member of the inlet port is in a closed state; the absolute gas pressure inside the closed inner space is strictly less than the standard atmospheric pressure, such that the device is able to create suction through the inlet port during a first opening of the open/close member.

NUCLEIC ACID EXTRACTION MICROFLUIDIC CHIP, AND NUCLEIC ACID EXTRACTION DEVICE AND EXTRACTION METHOD
20220333048 · 2022-10-20 ·

Embodiments of the disclosure provide a nucleic acid extraction microfluidic chip, and a nucleic acid extraction device and method. The nucleic acid extraction microfluidic chip includes a channel plate including: a mixed lysis zone, an extraction zone adjacent to the mixed lysis zone, a gas-pressure driven port in communication with an exterior, a first type of channel communicating the mixed lysis zone with the extraction zone, and a second type of channel communicating the extraction zone with the gas-pressure driven port; a cover plate opposite to the channel plate, wherein the cover plate includes a sample inlet and a liquid inlet through hole in a location corresponding to the mixed lysis zone; and a solution accommodating cavity, on a side of the cover plate away from the channel plate, wherein the solution accommodating cavity communicates with the mixed lysis zone of the channel plate through the liquid inlet through hole.

MICROFLUIDIC DEVICE FOR ANALYZING A MEMBRANE

A microfluidic device for analyzing permeability of substances through a membrane. Flow channels pass respective fluid flows with the substances through the housing between respective connectors. An access cavity extends from outside into the housing through the first flow channel and into the second flow channel for accessing an inside of the housing. The membrane can be placed over a cavity opening forming a fluid interconnection between overlapping areas of the flow channels A clamping ring in the first flow channel holds the sample membrane in place over the cavity opening while the membrane is exposed to the respective fluid flows through the flow channels on either sides of the membrane.

PIPETTING DEVICE AND A METHOD OF PROCESSING A FLUID SAMPLE
20230073005 · 2023-03-09 ·

A pipetting device for processing a fluid sample includes a receiving element and a pipette tip detachably arranged on the receiving element, a displacement element flow-connected to the pipette tip for generating a flow for receiving or ejecting the fluid sample. The pipetting device includes an optically transparent extension detachably arranged on the pipette tip in such a way that the extension is flow-connected to the displacement element via the pipette tip, so that the fluid sample can be received into the extension or can be ejected from the extension by the flow that can be generated by the displacement element.

SAMPLE CONTAINER
20220314213 · 2022-10-06 ·

The present invention relates to a sample container having a new structure to effectively transfer a sample. A sample container according to the present invention includes: a container main body 10 that is formed in a cup shape having an open top surface, and a coupling hole 11 opened in a vertical direction is formed on one side of the container main body 10; a closed and sealed cover 20 that is coupled to an upper end of the container main body 10 to close and seal the container main body 10; and a detachably coupled collection tube 30 that is formed in the shape of a tube that extends in a vertical direction while having an open top surface, and is detachably coupled to the coupling hole 11, wherein a slope 12 that is inclined downward to the inside of the container main body 10 is formed on one side of an external circumferential surface of the container main body 10, wherein a recess portion 13 of which a lower end is open, and the recess portion 13 is formed on one side of the external circumferential surface of the container main body 10, and wherein the coupling hole 11 is formed to penetrate top and bottom surfaces of the recess portion 13, and the coupling hole 11 is formed on the top surface of the recess portion 13, accordingly, there is a merit that, after containing urine in the container main body 10 and combining the closed and sealed cover 20, the container main body 10 can be tilted to easily transfer urine to the collection tube 30 and the urine can be prevented from outflowing and contaminating the surrounding area, being contaminated, or being mistakenly switched.

Disposable Flow Through Diagnostic Device and Method of Construction Thereof

A disposable diagnostic device includes a body having a first channel and a second channel spaced from the first channel. A shroud is operably fixed to the body and encloses a chamber which is configured in a hermetically sealed-off relation from the first and second channels when the device is in a non-activated first state and is in open communication with at least one of the first and second channels when the device is in an activated second state. A reactant and an inert gas are disposed in the chamber such that the inert gas protects the reactant from being exposed to contaminants when the device is in said non-activated first state. A method of constructing a disposable diagnostic device is also disclosed.

CENTRIFUGAL REACTION MICROTUBE, CENTRIFUGAL REACTION DEVICE AND ITS CENTRIFUGAL EXAMINATION METHOD
20220314214 · 2022-10-06 ·

A centrifugal reaction microtube, centrifugal reaction device and its centrifugal examination method are provided to achieve easy, quick operation, safety, energy saving, precision, cost effectiveness, and prevention of contamination by controlling a centrifugal force and using a uni-directional valve in the centrifugal reaction microtube.

Metering arrangement in a capillary driven fluid system and method for the same
11618020 · 2023-04-04 · ·

The disclosure relates to an arrangement (100) in a capillary driven fluid system for metering a predetermined volume of sample fluid. The arrangement comprises a sample reservoir (SR) arranged to receive a sample fluid, a first channel (C1) which is in fluid communication with the sample reservoir (SR) and which branches off into a second channel (C2) ending at a first valve (V1) and a third channel (C3) ending at a second valve (V2). The second channel (C2) and the third channel (C3) together have a predetermined volume, and the first channel (C1) is arranged to draw sample fluid from the sample reservoir (SR) by use of capillary forces to fill the second channel (C2) and the third channel (C3) with the predetermined volume of sample fluid. By selectively opening the first valve (V1) and the second valve (V2), a capillary driven flow may be formed, thereby causing the predetermined volume of sample fluid to flow out through the first valve (V1).

Domino capillary microfluidic circuit

There is disclosed a capillary microfluidic circuit including a main channel communicating with a flow inducing element. The main channel has intermediary inlets. Reservoirs for containing one or more liquids prior to being drawn into the main channel. The reservoirs include a first reservoir and at least a second reservoir. Each of the reservoirs has an upstream end connectable to vents for filling the reservoirs with the one or more liquids and a downstream end. The downstream end of each of the reservoirs is connected to the intermediary inlets of the main channel A conduit is disposed between the first reservoir and the a least a second reservoir. The conduit links the downstream end of the first reservoir with the upstream end of the at least a second reservoir.

MICROFLUIDIC POINT-OF-CARE ASSAY

The disclosure describes an integrated fluid sample test strip comprising: an inlet for receiving solutions comprising a fluid sample and a substrate solution, the inlet comprising a retention valve for temporarily retaining each solution to thereby reduce air flow through the valve; a reaction chamber to receive the solutions via the retention valve, the chamber functionalized with bioreceptor(s); a capillary pump to receive from the reaction chamber the solution(s), the pump comprising vent hole(s); a test chamber to receive the substrate solution from the reaction chamber, the test chamber comprising test electrodes for a biosensing test of the substrate solution; a hydrophobic vent hole coupled to the test chamber to allow a flow of solution from the reaction chamber into the test chamber when the vent hole is unsealed and to allow a flow of solution from the reaction chamber to the capillary pump when the vent hole is sealed.