A tissue processing system for processing a laboratory slide includes a slide holder for holding the slide, an outlet port positioned to direct a fluid stream onto the slide, and a device for moving the slide holder relative to the outlet port, or vice versa, to adjust a point on the slide at which the fluid stream is delivered onto the laboratory slide. The slide holder includes an absorbent pad configured to be positioned between one wall of the plurality of walls and a free edge of the slide for absorbing fluid travelling along the slide. A manifold of the system includes a first outlet port that directs a first fluid stream from a first fluid passageway onto the slide, and a second outlet port that directs a second fluid stream from a second fluid passageway onto a location of the slide that differs from the first fluid stream.

Vial assemblies comprising a tubular body and a flexible bottom or flexible liner are described herein, wherein the flexible bottom or liner is configured to compress at least partially upon the application of force. Methods for storing and removing frozen samples from such vial assemblies are also described herein.

An apparatus for storing blood plasma separated after fractionation from whole blood within a wrapped hematocrit (capillary) tube. The apparatus is large enough to receive and display a standard laboratory identification label. The apparatus stores plasma from a hematocrit tube that does not include thixotropic gel. The apparatus housing has an intended upright orientation, a central axis, a top end, a bottom end, and side walls defining an internal cavity. A wall with an upper surface and a lower surface divides the internal cavity into an upper cavity and a lower cavity. A reservoir is formed in the upper cavity. A removable cap seals the reservoir. The cap is movable between open and closed positions. A channel within the lower cavity extends axially from the bottom of the housing to the wall. The channel receives and supports the wrapped hematocrit tube while plasma is expelled therefrom and into the reservoir.

A device (100) having a proximal end (20) and end a distal end (40) for withdrawal of a liquid sample, fractionation, and separation of one or more fractions comprising: a piston assembly (300) comprising a piston (302) dismountably attached at its proximal end (20) to an actuating rod (350); a container (200) having a body (202) disposed with a cylindrical chamber (204) for slidable movement of the piston (302) therein; wherein the cylindrical chamber (204) is provided at the distal end (40) with a resealable septum (410) for co-operation with a puncture needle assembly (600) for withdrawal of the liquid sample, an at the proximal end (20) with a stop member (206), which stop member (206) limits movement of the piston (300) in a proximal direction, wherein the container body (202) is dimensioned to fit inside a centrifuge rotor, and is configured for breakability into two parts at a temperature of 0 deg C. or lower at a breakable zone (210).

Provided are devices, methods, and systems for temperature control of individual containers in a thermocycler for polynucleotide synthesis. Provided herein are devices, methods, and systems comprising a circuit patch having a heating element that is placed over a reaction container on a lid of the reaction container or directly over the reaction container Provided herein are devices, methods, and systems comprising a single-piece sensor assembly for a thermistor plate assembly comprising a sensor holder having a sensor pad that is in contact with the container holder.

A system for diagnostic testing may include a meter for performing a diagnostic test on a sample applied to a test media, the meter having a housing and an interface for receiving a signal representing coding information, and a container configured to contain test media compatible with the meter, the container having a coding element associated therewith. Additionally, the system may provide a mechanism for removing the meter from an interconnected test container and reattaching it to a new container using on-container coding methods that can recalibrate the meter for the new container of test strips.

A blood biomarker analysis systems providing fast biomarker identification includes a multimodal bioassay device having a biosensor within a portable pipette-shaped device and using nanoplasmonic barcode detectors, such as formed of antibody conjugated gold nanoparticle arrays (AuNPs), capable of capturing any of a plurality of biomarkers. The biomarker analysis system further includes the pipette-shaped device being smartphone-connected and portable to form a highly accurate, point-of-care bioassay device.

A heat sealing product suitable for seating one or more individual containers, said heat sealing product comprising: (i) a plurality of individual heat seals set out in a configuration substantially corresponding to the shape and configuration of the container(s) to be sealed, the size and shape of the individual heat seals corresponding substantially to the size and shape of the tops of the individual container(s) to be sealed; (ii) a peelable support film layer coated on one side with a low tack adhesive, the low tack adhesive serving to hold the individual heat seals in place on the support film layer in the desired configuration prior to the sealing process; (iii) alignment points in the sealing product adapted to enable the heat sealing product and therefore the individual heat seals of the heat sealing product to be aligned substantially exactly with respect to the individual containers to be sealed.

Provided herein are methods of amplifying and detecting biothreat pathogens in complex samples (e.g., blood), as well as related panels and compositions (e.g., systems, cartridges, and kits).

Sub-millimeter scale three-dimensional (3D) structures are disclosed with customizable chemical properties and/or functionality. The 3D structures are referred to as drop-carrier particles. The drop-carrier particles allow the selective association of one solution (i.e., a dispersed phased) with an interior portion of each of the drop-carrier particles, while a second non-miscible solution (i.e., a continuous phase) associates with an exterior portion of each of the drop-carrier particles due to the specific chemical and/or physical properties of the interior and exterior regions of the drop-carrier particles. The combined drop-carrier particle with the dispersed phase contained therein is referred to as a particle-drop. The selective association results in compartmentalization of the dispersed phase solution into sub-microliter-sized volumes contained in the drop-carrier particles. The compartmentalized volumes can be used for single-molecule assays as well as single-cell, and other single-entity assays.