B01L2300/023

Solid reagent containment unit, in particular for a portable microfluidic device for sample preparation and molecule analysis

A solid reagent containment unit is formed by a support; a frame body fixed to the support and delimiting internally, together with the support, an analysis volume; a reagent-adhesion structure within the analysis volume; and at least one reagent cavity, which extends within the reagent-adhesion structure. The reagent-adhesion structure is of an adhesion material embossable at temperatures lower by 6-8° C. than its own melting point and has a melting point such as not to interfere with the analysis. The reagent cavity forms a retention wall, laterally surrounding the reagent cavity, and houses dried reagents. The adhesion material is chosen among wax, such as paraffin, a polymer, such as polycaprolactone, a solid fat, such as cocoa butter, and a gel, such as hydrogel or organogel.

DEVICE FOR READING, PROCESSING AND TRANSMITTING TEST RESULT DATA FOR PATHOGENS OR VIRUSES IN FLUID TEST SAMPLES
20220369964 · 2022-11-24 ·

The embodiments disclose a test cartridge assembly system including a test cartridge assembly for loading of a test sample moving the fluid through the internal fluidic channels processing and presenting the sample to one or more electrochemical sensors for measuring analytes in the test sample, at least one fluidic channel formed directly in a rigid portion of an upper test cartridge assembly housing to form a fluidic path, a port coupled to the at least one fluidic channel for receiving a spring loaded vacuum source, a port coupled to the upper test cartridge assembly housing to communicate the vacuum through the upper cartridge housing into the fluidic path, and a functional layer coupled to the test cartridge assembly configured to provide electrical functionalities and interconnections to various fluidic components.

Monitoring apparatus for temperature-controlled sample collection and transport

A system is provided for transporting, handling and monitoring samples in a temperature-controlled storage environment. The system includes a handheld carrier configured to transfer samples to and from a temperature-controlled storage station and a temperature-controlled container for receiving and housing one or more carriers. The carrier includes an integrated sample identification and temperature sensing capability configured to monitor a thermal history of one or more samples during transport, handling and storage including as the samples are conveyed between the temperature-controlled storage environment and the temperature-controlled container. That is, the carrier is adapted to be held in the hand during use. A carrier for conveying and monitoring samples during transport, handling and storage is also provided.

Hotplate stirrer

A hotplate device has a body with a platform for receiving a vessel that contains a sample to be heated. A heating element, arranged under the platform, provides heat to the platform, based on a set temperature and a measured temperature as sensed by at least one temperature sensor, proximate to the platform. A controller located in the body directs electrical power to the heating element. As a safety feature, a wireless communication feature allows a user to enter set temperature instructions from a mobile device when communication with the mobile device is enabled and established. A proximity feature, when enabled, allows the user to enter instructions only as long as the user remains in a predetermined proximity of the hotplate device.

SOLID REAGENT CONTAINMENT UNIT, IN PARTICULAR FOR A TRANSPORTABLE MICROFLUIDIC DEVICE FOR SAMPLE PREPARATION AND MOLECULE ANALYSIS

A solid reagent containment unit is formed by a support; a frame body fixed to the support and delimiting internally, together with the support, an analysis volume; a reagent-adhesion structure within the analysis volume; and at least one reagent cavity, which extends within the reagent-adhesion structure. The reagent-adhesion structure is of an adhesion material embossable at temperatures lower by 6-8° C. than its own melting point and has a melting point such as not to interfere with the analysis. The reagent cavity forms a retention wall, laterally surrounding the reagent cavity, and houses dried reagents. The adhesion material is chosen among wax, such as paraffin, a polymer, such as polycaprolactone, a solid fat, such as cocoa butter, and a gel, such as hydrogel or organogel.

Method of information transmission, a liquid handling device, and a system

According to an example aspect of the present invention, there is provided a method of information transmission in a system comprising at least one liquid handling device and at least one external device, the method comprising: in one or more of said at least one liquid handling device, producing a machine-readable code that contains information that is derived from a status or properties of the respective liquid handling device or information that has been stored in the respective liquid handling device; in said one or more of said at least one liquid handling device, displaying the respective code on a display that is integrated to a structure of the respective liquid handling device; reading the displayed code or one or more of the displayed codes by an external device.

Toilet with infrastructure for analytical devices

An analytical toilet comprising a bowl for receiving excreta from a user; a base supporting the bowl; a supply of flush water; and a plurality of receptacles, each providing mechanical attachment, a power supply, and a data connection to an analytical device, which analytical device is adapted to provide data useful to the user is disclosed.

BIOLUMINESCENT SINGLE PHOTON BIOREACTOR AND PERFORMING ABSOLUTE QUANTIFICATION OF LIGHT-PRODUCING ACTIVITY BY ENZYMES
20220364144 · 2022-11-17 ·

A bioluminescent single photon bioreactor for performing absolute quantification of light-producing activity by enzymes includes: a bioreactor that produces a bio-electronic signal; an electronic sensor that receives the bio-electronic signal and produces an electrical transduction signal; and an analyzer that receives the electrical transduction signal and absolutely quantifies light-producing activity by enzymes from the electrical transduction signal, such that the absolute quantification is accomplished quantum mechanically by determination of a second order autocorrelation function.

Multiplexed sensor for ultra-fast and low-cost COVID-19 diagnosis and monitoring

A biosensor for the rapid, inexpensive, quantitative, and convenient detection of SARS-CoV-2 biomarkers, methods of manufacturing, and methods of using the same, to identify a patient's prognosis and past/present SARS-CoV-2 infection status, wherein the biosensor comprises a microfluidics layer, a multimodal sensing layer comprising two or more working electrodes, and a logic circuit that may include a processor and non-transitory memory with computer executable instructions embedded thereon.

LATERAL FLOW ASSAY HOUSING WITH INTEGRATED SAMPLE AND BUFFER SOLUTION DELIVERY AND MEASUREMENT
20230031715 · 2023-02-02 ·

A lateral flow assay (LFA) device includes a capillary pad and a sample port that holds the sample fluid before a hole is made in a cavity surface of the sample port. The LFA device includes a breaker with a tip to make a hole in the cavity wall of the sample port causing the sample fluid held inside the compartment to be applied to the capillary pad after the start of a test.