A control button (12) for a manually actuated sampling pipette, the button including lower and upper parts (24a, 24b), one of which is equipped with a force sensor (31) and the other with an actuating member (30). In the vertical position of the button, in a state not subjected to a force, not only does the member (30) ensure that the upper part is retained axially on the lower part (24a), but these parts also define a circular axially retaining connection (42) therebetween, the circular connection exhibiting an axial clearance (47) configured such that, when a pressure is exerted on an off-centre action zone (102a) by the thumb of an operator, the axial clearance (47) is taken up in this zone (102a), while the connection (42) retains a reaction zone (102b), arranged diametrically opposite the action zone (102a), axially and locally relative to the lower part (24a).

Described herein is an integrated automated nucleic acid sample preparation, detection and analysis system, along with methods of operating such a system. Also described are methods of methods of analyzing nucleic acid molecules in a sample and methods of determining a melting curve of a nucleic acid sample. The automated system includes a robotic pipettor comprising one or more pipettes movable in a horizontal plane and configured to dispense or withdraw one or more liquids, a robotic arm configured to transport a plurality of connected sample processing tubes, a nucleic acid isolation system comprising a first sample processing tube holder configured to hold the plurality of connected sample processing tubes, and magnet, wherein magnetically-responsive particles contained within each sample processing tube are retained within the sample processing tube upon withdrawing of liquid by the robotic pipettor when the magnet is in an active configuration; and a fluorometer comprising a light source and an optical detector disposed below a second sample processing tube holder configured to hold the plurality of connected sample processing tubes, the second sample processing tube holder having a clear or open bottom, wherein the fluorometer is configured to detect fluorescence emitted from a sample in one or more of the sample processing tubes.

A detection method of detecting CTCs as target cells contained in a test sample, the method includes a concentration step of concentrating the target cells contained in the test sample, a labeling step of labeling the target cells and other components by bringing the concentrated test sample into contact with first labeling antibodies in which antibodies specifically binding to antigens, which exclude antigens expressing in epithelial cells and specifically express in the target cells, are labeled by a first labeling substance, and into contact with second labeling antibodies in which antibodies binding to antigens expressing in the other components excluding the target cells are labeled by a second labeling substance, and a detection step of detecting, from the test sample, cells that are labeled by the first labeling antibodies and are not labeled by the second labeling antibodies as the target cells.

Among other things, the present disclosure is related to devices and methods for containing a liquid sample between two plates.

Disclosed is a sample analyzer including a storage section configured to store a plurality of containers for containing a sample, and including a discharge port through which the container is discharged; a production lot information acquisition unit that acquires production lot information on a production lot of the container; an analysis processing unit that performs analysis processing of the sample contained in the container discharged through the discharge port; a recorder that records the production lot information, an analysis result of the sample contained in the container, and time information related to time of analyzing the sample; and a display information generation unit that generates, based on information recorded in the recorder, display information for displaying at least one analysis result of at least one sample analyzed during a period of time on a display unit in a manner that associates the at least one analysis result with the production lot information.

Among other things, the present invention is related to devices/apparatus and methods of performing cellular, biological, and chemical assays and procedures.

A portable testing device includes a hosing with an integrated touchscreen display and a receptacle in which a sample holder containing a biological sample and reagent mixture can be placed. The portable testing device further includes an optical assembly positioned in the housing, an electronic assembly that is configured to receive data from the optical assembly and transmit it for display upon the touchscreen display, and a power supply in the housing to power the portable testing device. The optical assembly includes an excitation filter that extends across the entire optical assembly and an emission filter that extends across the entire optical assembly.

The present application relates to a method for detecting and monitoring the level of thyroid hormones in an individual and a device for carrying out the same.

A temperature control device has: a sample container holder that holds a sample container; multiple temperature sensors that measure the temperature near a sample; a temperature control element that heats or cools the sample container holder; a storage unit that stores a mathematical model; and a computation unit that analyzes the mathematical model based on the sensors. The mathematical model serves as a thermal network model in which nodes and a thermal resistance between predetermined nodes are set, the nodes corresponding at least to the sample, sample container, sample container holder, sensors, and temperature control element. Each node has a predetermined heat capacity, and the computation unit uses a state estimation algorithm to calculate a thermal resistance estimated value between the sample container and the sample container holder and a temperature estimated value of the sample, based on the output from each of the sensors and the thermal network model.

A testing system and method for providing a testing system includes a user interface having a display for displaying information relating to measurements of health data and an input device for receiving information from a user relating to the health data. Provided in connection with the user interface is an autologging feature adapted to provide the user with user-selectable options on the display. Also provided is a statistical operation adapted to provide the user with enhanced information relating to the measurements of health data. Also provided is at least one indicator for indicating information relating to the number of health data readings that are within a target range, the number of health data readings that are above the target range and the number of health data readings that are below the target range.