B01L2300/0832

SAMPLE COLLECTION AND PRESERVATION DEVICES, SYSTEMS AND METHODS
20230064804 · 2023-03-02 ·

The present disclosure provides systems, methods, devices, and kits for analysis of vaginal biological samples. A device for the analysis of vaginal biological samples can include a sample collector, an extractor, and an assay cartridge. A method for the analysis of vaginal biological samples can include detecting the presence or absence of a pathology, a disease, an immune disorder, a reproductive disorder of a subject. The method may further comprise preserving, storing, or transporting the vaginal biological samples. A kit for the analysis of vaginal biological samples can include probe, reagents and instructions for detecting a nucleic acid in the vaginal biological samples.

ANTIGENIC DETECTOR
20230122646 · 2023-04-20 ·

The present application discloses an antigenic detector, including: a pen holder and a pen cap. The pen holder includes: a test paper tube, a test paper assembled in the test paper tube, a test paper support, and a foam support installed on the front end of the test paper tube with a foam and a protective cover; the pen cap includes: a base, an aluminum foil assembled in the base, and an interior of the base forms a cavity into which a front end of the pen holder is inserted, and a reaction solution is sealed inside the cavity of the base by the aluminum foil; the protective cover is detachably installed on the front end of the test paper tube and covers the foam; the foam support is provided with a channel that communicates with an interior of the test paper tube.

Sample Container Handling System
20230116923 · 2023-04-20 ·

The present invention relates to a sample container handling system (1), having a sample container receptacle (2) and a support element (20). The sample container receptacle (2) in turn has: holding structures (4, 5) which are each configured to hold a respective sample container (3) and which are disposed about a rotation axis (6), and a base (7) having a support region (8) for supporting the sample containers (3) held by way of the holding structures (4, 5), wherein the base (7) furthermore has a side (10) that faces away from the support region (8) and at least one through opening (11) which from this side (10) extends to the support region (8). The support element (20) is connectable to the base (7) of the sample container receptacle (2) in such a manner so as to receive the latter, wherein the support element (20) has at least one protrusion (25, 26, 27) which, when the support element (20) receives the sample container receptacle (2), extends through the at least one through opening (11) and for lifting one or more sample containers (3) projects from the support region (8). The invention furthermore relates to a system having the sample container handling system (1) and a pressure container having a reaction chamber in which the sample container receptacle (2) is able to be received or is received.

Sample collection and detection device and method
11630036 · 2023-04-18 · ·

A sample collection and detection device includes a collection cavity. The device further includes a sample collector. The sample collector comprises a collection rod and an absorption element, and the absorption element has a hollow cavity. A part of the collection rod is received in the hollow cavity of the absorption element. A first lug for blocking and locating the absorption element is arranged on the collection rod. Also provided is a method for collecting and detecting sample using the sample collection and detection device.

Assay plate and uses thereof

An assay plate assembly comprising a plurality of microfluidic modules arranged in a rectilinear matrix of rows and columns microfluidic channels. Each microfluidic module has an inlet well leading to a serpentine microfluidic channel that is set at a cant angle. The well is laterally offset from the detection area to avoid optical interference. The geometric center of each detection area is positioned according to ANSI/SLAS standards for well-centers. A drain from each microfluidic channel is located so that it does not interfere with any detection areas. An array of micro-posts are disposed within each microfluidic channel. The micro-posts extend perpendicularly from the top surface of the top plate toward the underside and are equally distributed throughout the entire detection area. The plate assembly provides reduced assay time and sample volume, and increased sensitivity and specificity in biological and chemical assays.

Testing System For Pathogens and Analytes

A device to detect pathogens and/or analytes in a test sample is designed to include a core, which may have first and second chambers. The first chamber is designed to accept a combination of a test specimen and a buffer liquid. A piston is designed to slideably engage into the first chamber of the core, wherein the end of the piston may engage with the bottom of the first chamber and be capable of grinding the test specimen. A plunger is designed to slideably engage with the second chamber of the core, and is in fluid communication with the first chamber. An assay section is attached to the core, and is in fluid communication with the second chamber. The assay device is designed to include a test strip that is capable of detecting and indicating the presence of pathogens and/or analytes in the combination of the test sample and buffer liquid.

Sample collection device
11660078 · 2023-05-30 · ·

A sample collection device including a collection tube at least partially defining a storage volume therein, a mouthpiece coupled to the collection tube, the mouthpiece defining a channel providing access to the storage volume, and a filter at least partially positioned within the channel, where the filter is configured to filter a sample as it passes through the channel and into the storage volume.

Molten metal sampler

The present invention relates to a sampler for taking samples from a molten metal bath, particularly a molten iron, the sampler comprising: a carrier tube having an immersion end; and a sample chamber assembly arranged on the immersion end of the carrier tube, the sample chamber assembly comprising a cover plate and a housing, wherein the housing comprises: an immersion end having a first opening for an inflow conduit and an opposing end having a second opening for a gas coupler, a first face extending between the immersion end and the opposing end, the first face having a first depression proximate the immersion end and a second depression, the first depression being an analysis zone and the second depression being a ventilation zone, a portion of the analysis zone overlying a distribution zone which is in direct flow communication with the first opening and configured to receive the molten steel from the inflow conduit, wherein the first depression having a cross sectional circle segment profile along a central longitudinal axis that is concavely or triangularly shaped, wherein the cover plate and the housing are configured to be assembled together to form a sample cavity including the distribution zone, the analysis zone and the ventilation zone, such that an analysis surface of a solidified steel sample formed within the sample cavity lies in a first plane, and wherein the first and second openings are spaced apart from the first plane. The invention also relates to a sampler for taking samples from a molten metal bath, particularly a molten iron, the sampler comprising: a carrier tube having an immersion end; a sample chamber assembly arranged on the immersion end of the carrier tube, the sample chamber assembly comprising a cover plate and a housing, wherein the cover plate comprising a sealing member configured to provide a substantially gas tight seal between the cover plate and the housing, wherein the sealing member consist of an essentially non-contaminating material for the samples in the sample chamber.

SET OF CHAMBERS CONTAINING REAGENTS
20230158492 · 2023-05-25 ·

The invention relates to a system is provided that comprises a first container, a second container and a fluorescence detection device. The first container comprises a first set of chemicals and/or agents and is closed prior to use. The second container comprises a second set of chemicals and/or agents that are at least in part distinct from the chemicals and/or agents of the first set. The first container comprises a lid, that can be opened when the first container and the second container are combined to form a single, fluid tight assembly, in order to allow the contents of the first container to enter the second container.

BIODEGRADABLE PIPETTE TIP RACK
20230158509 · 2023-05-25 ·

An environmentally enhanced pipette tip rack includes a molded fibrous cellulose shell and an injection molded plastic tip deck; the shell and other features of the rack are configured for strength, minimal contamination, and to be biodegradable, compostable, or recyclable.