A fluidic card assembly (1) comprises an inlet (20) for introducing a fluid to the fluidic card assembly (1), a turbulent flow portion (30) downstream of the inlet (20), the turbulent flow portion (30) comprising a widening fluid channel (31) whereby a fluid introduced via the inlet (20) channel undergoes turbulence, and a laminar flow portion (40) downstream of the turbulent flow portion (30). The laminar flow portion (40) is configured to allow fluid passing from the turbulent flow portion (30) into the laminar flow portion (40) to establish a laminar flow pattern, and is configured to house a biochip (44) such that a fluid in the laminar flow portion (40) may be in contact with the biochip (44).

A culturing device includes a microplate including a plurality of vessels, each of the vessels having a bottom surface having light transmittance and an opening at an upper portion, a lid having light transmittance, and an intermediate plate having light transmittance sandwiched between the lid and the microplate. The intermediate plate has a plurality of convex portions on a surface thereof facing the microplate and provided with a plurality of through holes corresponding to the convex portions that are disposed so that when the intermediate plate and the microplate are overlapped, each of the plurality of convex portions is inserted into each of the plurality of vessels and each of the plurality of through holes coincides with the opening of each of the plurality of vessels. The lid comes into contact with the intermediate plate so as to close the plurality of through holes provided in the intermediate plate.

Methods for forming arrays of droplets, and associated arrays of droplets, are generally provided.

Limit size lipid nanoparticles, methods for using the lipid nanoparticles, and methods and systems for making limit size lipid nanoparticles.

A thermal cycler system comprises a sample block configured to receive a sample holder configured to receive a plurality of samples; an adaptor configured to surround a periphery of the sample block; and a drip pan configured to surround a periphery of the adaptor. The drip pan comprises one or more ejector mechanisms and one or more openings, the one or more ejector mechanisms configured to respectively extend through the one or more openings into contact with the sample holder in a state of the sample holder received by the sample block and the adaptor surrounding the periphery of the sample block.

The invention relates to a cartridge for an analysis method which is rotation-based and utilizes one-sided heat input. The cartridge has a planar main body in which a microfluidic channel-and-chamber structure is formed, with channels interconnecting multiple process chambers, a number of positioning and/or fastening elements, formed in the main body, for positioning and/or fastening the main body on/to a support plate of an analyzer for carrying out the analysis method, and a cover body which is fastened to the main body and which is one-sidedly arranged on a top side of the main body that faces away from a heat input side and which covers at least a chamber.

A first aspect of the invention relates to a syringe housing which can have the following elements: a syringe body which has a first open end and a second open end, a first channel being formed between the two ends; a first membrane which is arranged such that the membrane extends substantially perpendicularly to the longitudinal direction of the first channel over the cross-section thereof; a syringe body attachment which has a first open end and a second open end, a second channel being formed between the two ends; a second membrane which is arranged such that the membrane extends substantially perpendicularly to the longitudinal direction of the second channel over the cross-section thereof; wherein the second open end of the syringe body and the first open end of the syringe body attachment are designed so as to be connectable in a formfitting manner and thus form the syringe housing, the first channel and the second channel form a continuous channel in the connected state of the syringe housing, and the first membrane and the second membrane define an extraction volume in the region of the continuous channel. Furthermore, different embodiments provide a pipette device which is designed for the automatic use of the syringe housing according to the invention.

A target analysis tool and a target analysis method that allow easily analysis of a target. The first target analysis tool includes: a first chamber; a second chamber; and a third chamber. The first chamber, the second chamber, and the third chamber are disposed continuously in this order. The first chamber contains, as a first reagent, an immobilized first binding substance obtained by immobilizing, on a carrier, a first binding substance that binds to a target. The second chamber contains, as a second reagent, a labeled second binding substance obtained by binding a labeling substance to a second binding substance that binds to the first binding substance. The third chamber is a detection section in which the labeled second binding substance is detected.

A tube holder assembly includes a base plate, an attachment plate, and an optional securing element. The base plate may include guides into which protrusions of the attachment plate slide to alter the positioning apparatus from an open position to a closed position. The base plate also includes receivers to receive tubular members, which have their movement restrained by the receivers and the securing elements in the closed position. The tube holder assembly may also include a latch to help maintain the closed position during operation.

A separation container for extracting a portion of a sample for use or testing and method for preparing samples for downstream use or testing are provided. The separation container may include a body defining an internal chamber. The body may define an opening, and the body may be configured to receive the sample within the internal chamber. The separation container may further include a seal disposed across the opening, such that the seal may be configured to seal the opening of the body, and a plunger movably disposed at least partially inside the internal chamber. The plunger may be configured to be actuated to open the seal and express the portion of the sample.