B01L2300/126

SYSTEM FOR ANALYSIS
20230264194 · 2023-08-24 ·

There is provided a device for analysis of sample liquid, the device comprising a microfluidic test card, and a microfluidic chip for processing the sample liquid presented from the microfluidic test card and return processed sample fluid to the microfluidic test card. The microfluidic test card comprises a sample inlet, configured for receiving sample liquid, first and second pre-processing test reagent channels having first and second test reagent outlets, respectively, for presenting test reagent to the microfluidic chip, a pre-processing sample channel fluidically communicating with the sample inlet for receiving sample liquid therefrom, and having a sample liquid outlet for presenting the sample liquid to the microfluidic chip, first and second processed sample analysis channels for receiving processed sample liquid from the microfluidic chip, wherein the first and the second processed sample analysis channels comprising a first and second analysis zone, respectively, for analysing the processed sample liquid, and a microfluidic chip contacting zone comprising said sample liquid outlet and first and second test reagent outlets, configured for connection and fluidic communication with the microfluidic chip.

Sampling Device
20230264190 · 2023-08-24 ·

A device for use in the separation of biological samples into a solid component and a liquid component. The device comprises a front cover and a back cover connected at a hinge portion such that the device is operable between an open position and a closed position. A separation membrane is arranged to retain the solid component and to allow the liquid component to pass therethrough, and an absorption membrane is arranged to retain the liquid component. The separation and absorption membranes are arranged in a layered structure between the front and back covers. Opening the device from the closed position to the open position causes the separation and absorption membranes to bend, thereby applying a compressive force to the membranes.

Paperfuge: An integrated paper-based centrifugation and microfluidics platform for low-cost diagnostics

A microfluidic centrifuge is provided that includes a microfluidic disc having a pair of through holes that include a first through hole and a second through hole, where the pair of through holes are disposed symmetric and proximal to a central axis of the microfluidics disc, where the microfluidics disc includes a sealable input port and a sealable output port, where the sealable input port and the sealable output port are connected by a microfluidics channel, and a pair of tethers disposed through the pair of through holes that are disposed to twist about each other for unwinding where the tether unwinding is disposed to interact with the through holes, where the microfluidics disc rotates about the central axis.

A NON-INVASIVE PAPER BASED DEVICE FOR PREGNANCY DETECTION IN CATTLE AND BUFFALOES

The present invention discloses a kit and a novel method of extraction of a progesterone metabolite from feces/dung sample. The present invention also discloses a paper-based microfluidic device for detection of the progesterone metabolite for early determination of pregnancy in cattle and buffaloes. The invention further discloses antibodies developed against said metabolite, method of extraction, methods for fabricating the paper-based microfluidic devices and methods for inexpensive, rapid and non-invasive determination of pregnancy in early stages in cattle and buffaloes.

SWAB WITH RECEPTACLE PROVIDING INTEGRATED DRYING
20230258539 · 2023-08-17 ·

Described herein is a device for collecting and drying and protecting oral or nasal swab samples that can then be submitted for antibody and/or molecular testing.

MICROFLUIDIC PRESSURE IN PAPER (.Math.PIP) FOR ULTRA LOW-COST PRECISION MICRO TOTAL ANALYSIS SYSTEMS
20230256430 · 2023-08-17 ·

A method for producing a microfluidic device includes creating a paper channel using a cutting device (e.g., a laser cutter, scissors, dies, blade, or the like), placing the paper channel between two sheets of PDMS, treating the PDMS sheets with a corona plasma to adhere the PDMS sheets together, and using heat to laminate the microfluidic device.

HOLDER FOR DRYING, METHOD OF MANUFACTURING MEASUREMENT SAMPLE, AND MEASUREMENT METHOD
20230258557 · 2023-08-17 ·

A holder for drying includes a first member including a first tubular portion that protrudes like a tube and an annular second member that can fix filter paper in a flat state under tension by being fitted over the filter paper to surround an outer side of the first tubular portion while the filter paper is carried on the first tubular portion.

Laboratory paper-structured weighing kit
11725979 · 2023-08-15 · ·

A laboratory weighing kit comprises two layers: a disposable paper-structured weighing boat in the upper layer and a corresponding-shaped weighing base in the lower layer. The weighing boat has a sample loading portion in the rear to carry chemicals or samples, and a funnel portion in the front to transfer samples. In order to consolidate storage space, either the front funnel can be opened to two portions or the back wall of the weighing boat is opened. The weighing boat can be creased to form a permanent fold. The weighing boat in the upper layer can be either removable from or permanently attached to the weighing base in the lower layer.

PAPER-BASED LOW-COST MICROFLUIDIC DEVICES FOR AUTOMATIC MULTISTEP PROCESSES

In an embodiment, the present disclosure pertains to a microfluidic device composed of a substrate having an inlet region and a first storage region, a fluid transporting channel in fluid communication with the inlet region, an expandable component in fluid communication with the fluid transporting channel and coupled to a movable arm, and a fluid transporting region coupled to the movable arm and operable to be moved in a horizontal direction to the fluid transporting channel to thereby form fluidic contact between the inlet region and the first storage region upon expansion of the expandable component. In an additional embodiment, the present disclosure pertains to a method of fluid flow utilizing a microfluidic device of the present disclosure.

Assay cartridges and methods of using the same

Assay cartridges are described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain embodiments, these cartridges are adapted to receive and analyze a sample collected on an applicator stick. Also described are kits including such cartridges and a cartridge reader configured to analyze an assay conducted using an assay cartridge.